Yu-Gi-Oh! (3-in-1 Edition), Vol. 8

Includes Vols. 22, 23 & 24

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Author: Kazuki Takahashi

Publisher: VIZ Media LLC

ISBN: 9781421579313

Category: Comics & Graphic Novels

Page: 592

View: 3682

Deuling dynamo Yu-Gi-Oh and his faithful friends battle their way through crazy games with high stakes and high risks! Tenth-grader Yugi always had his head in some game—until he solved the Millennium Puzzle, an Egyptian artifact containing the spirit of a master gambler from the age of the pharoahs! Possessed by the puzzle, Yugi becomes Yu-Gi-Oh, the King of Games, and challenges evildoers to the Shadow Games…weird games with high stakes and high risks! It’s Yugi and Kaiba vs. the Rare Hunters in a tag team match atop a 13-story skyscraper. But a fate worse than death awaits Yugi when he finds out Mai and Jonouchi have been possessed by Marik! Brainwashed by the evil mastermind, Jonouchi fights to kill his best friend. Will he succeed?

Yu-Gi-Oh! (3-in-1 Edition), Vol. 3

Includes Vols. 7, 8 & 9

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Author: Kazuki Takahashi

Publisher: VIZ Media LLC

ISBN: 9781421579269

Category: Comics & Graphic Novels

Page: 592

View: 6882

Tenth-grader Yugi always had his head in some game--until he solved the Millennium Puzzle, an Egyptian artifact containing the spirit of a master gambler from the age of the pharoahs! Possessed by the puzzle, Yugi becomes Yu-Gi-Oh, the King of Games, and challenges evildoers to the Shadow Games...weird games with high stakes and high risks! Game master Ryo Bakura wants to use the power of his Millennium Ring to put the souls of Yugi, Jonouchi, Anzu and Honda inside his “Monster World” miniatures forever. Now, with 10-sided dice in hand, Yugi and Dark Yugi must hack and slash their way their Bakura’s adventure and defeat the Dark Master Zorc…or die trying! Then, on the island called Duelist Kingdom, a battle royale is taking place to determine the greatest “Duel Monsters” player in the world! A fight with fisherman Ryota Kajiki is just a warmup for Yugi, the only person who’s beaten Kaiba, the former world champion. But although Kaiba may be in a coma, his deck still lives…in the hands of an evil ventriloquist, who has stolen not only Kaiba’s deck but his very soul!

Science and Civilisation in China: Volume 5, Chemistry and Chemical Technology, Part 9, Textile Technology: Spinning and Reeling

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Author: Joseph Needham,Dieter Kuhn

Publisher: Cambridge University Press

ISBN: 9780521320214

Category: History

Page: 556

View: 7938

This study, the first of two parts, gives a comprehensive account of Chinese textiles and textile technology and deals with the evolution of bast fibre spinning and silk-reeling in the history of China. These operations are the basic techniques in the production of yarn and thread, pre-requisite to weaving, and any study of Chinese textile technology must start with the raw material obtained from fibre plants such as hemp, ramie, jute, cotton, etc, and silk reeled off from cocoons of the domestic silkworm. The time-span covered runs from the neolithic to the nineteenth century. Archaeological and pictoral evidence, the bulk of it hitherto unpublished in the West, is brought together with Chinese textual sources (which are extensively translated and interpreted) to illustrate Chinese achievements in this field. Professor Kuhn's study reveals the way in which Chinese textile-technological inventiveness has influenced textile production in other regions of the world and in medieval Europe. It explains how textile technology reached its high point between the tenth and thirteenth centuries and attempts to indicate the reasons for its subsequent relative decline. The development of the textile industry in Europe was a key factor in the rise of capitalism. In the case of China after Sung times, textile technology and the organisation of textile labour may help indicate why such a development did not take place in China.

Cities in Post-Mao China

Recipes for Economic Development in the Reform Era

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Author: Jae Ho Chung

Publisher: Routledge

ISBN: 1134621914

Category: Social Science

Page: 320

View: 9665

This volume, written by contributors from a number of different specialisms, suggests that different combinations of factors have contributed to the relative successes and failures in these cities. Endowment factors, preferential policies, and history have all proved to be important. Most importantly, Cities in Post-Mao China suggests that locally-generated strategies of development are crucial determinants. This ground-breaking volume reveals through close detail and broad coverage how exactly cities have been catalysts for Chinas economic development. It will provide much needed data for those working in the fields of comparative politics, development studies, economic development and Asian studies.

Children's Books in Print, 2007

An Author, Title, and Illustrator Index to Books for Children and Young Adults

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Author: N.A

Publisher: N.A

ISBN: 9780835248518

Category: Authors

Page: N.A

View: 5484

Tailoring NK Cell Receptor-Ligand Interactions: an Art in Evolution, 2nd Edition

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Author: Ulrike Koehl,Antoine Toubert,Gianfranco Pittari

Publisher: Frontiers Media SA

ISBN: 2889456633

Category:

Page: 407

View: 317

Recognition and killing of aberrant, infected or tumor targets by Natural Killer (NK) cells is mediated by positive signals transduced by activating receptors upon engagement of ligands on target surface. These stimulatory pathways are counterbalanced by inhibitory receptors that raise NK cell activation threshold through negative antagonist signals. While regulatory effects are necessary for physiologic control of autoimmune aggression, they may restrain the ability of NK cells to activate against disease. Overcoming this barrier to immune surveillance, multiple approaches to enhance NK-mediated responses are being investigated since two decades. Propelled by considerable advances in the understanding of NK cell biology, these studies are critical for effective translation of NK-based immunotherapy principles into the clinic. In humans, dominant inhibitory signals are transduced by Killer Immunoglobulin Like Receptors (KIR) recognizing cognate HLA class I on target cells. Conversely, KIR recognition of “missing self-HLA” - due to HLA loss or HLA/ KIR mismatch - triggers NK-mediated tumor rejection. Initially observed in murine transplant models, these antitumor effects were later found to have important implications for the clinical outcome of haplotype-mismatched stemcell transplantation. Here, donor NK subsets protect against acute myeloid leukemia (AML) relapse through missing self recognition of donor HLA-C allele groups (C1 or C2) and/or Bw4 epitope. These studies were subsequently extended by trials investigating the antileukemia effects of adoptively transferred haplotype-mismatched NK cells in non-transplant settings. Other mechanisms have been found to induce clinically relevant NK cell alloreactivity in transplantation, e.g., post-reconstitution functional reversal of anergic NK cells. More recently, activating KIR came into the spotlight for their potential ability to directly activate donor NK cells through in vivo recognition of HLA or other ligands. Novel therapeutic monoclonal antibodies (mAb) may optimize NK-mediated effects. Examples include obinutuzumab (GA101), a glyco-engineered anti-CD20 mAb with increased affinity for the FcγRIIIA receptor, enhancing antibody-dependent cellular cytotoxicity; lirilumab (IPH2102), a first-in-class NK-specific checkpoint inhibitor, blocking the interaction between the major KIR and cognate HLA-C antigens; and elotuzumab (HuLuc63), a humanized monoclonal antibody specific for SLAMF7, whose anti-myeloma therapeutic effects are partly due to direct activation of SLAMF7-expressing NK cells. In addition to conventional antibodies, NK cell-targeted bispecific (BiKEs) and trispecific (TriKEs) killer engagers have also been developed. These proteins elicit potent effector functions by binding target ligands (e.g., CD19, CD22, CD30, CD133, HLA class II, EGFR) on one arm and NK receptors on the other. An additional innovative approach to direct NK cell activity is genetic reprogramming with chimeric antigen receptors (CAR). To date, primary NK cells and the NK92 cell line have been engineered with CAR specific for antigens expressed on multiple tumors. Encouraging preclinical results warrant further development of this approach. This Research Topic welcomes contributions addressing mechanisms of NK-mediated activation in response to disease as well as past and contemporary strategies to enhance NK mediated reactivity through control of the interactions between NK receptors and their ligands.

Video Sourcebook

A Guide to Programs Currently Available on Video in the Areas Of: Movies/entertainment, General Interest/education, Sports/recreation, Fine Arts, Heal

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Author: Thomson Gale

Publisher: Gale Cengage

ISBN: 9781414400990

Category: Performing Arts

Page: 4000

View: 5357

From classroom aids to corporate training programs, technical resources to self-help guides, children's features to documentaries, theatrical releases to straight-to-video movies, The Video Source Book continues its comprehensive coverage of the wide universe of video offerings with more than 130,000 complete program listings, encompassing more than 160,000 videos. All listings are arranged alphabetically by title. Each entry provides a description of the program and information on obtaining the title. Six indexes -- alternate title, subject, credits, awards, special formats and program distributors -- help speed research.