Search results for: vascular-dementia

Therapeutic Strategies in Dementia

Author : Craig W. Ritchie
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Widely acknowledged as one of the most challenging aspects of dealing with an aging population, the increasing prevalence of cognitive decline in the elderly presents the clinician with a variety of complex therapeutic problems. Alzheimer's disease and other dementias vary in their onset and progression, as do patients in their responsiveness to treatment. In this book, leading experts review the current and evolving therapeutic options, including anti-amyloid therapies, neuroprotective strategies, and symptomatic treatments (both pharmacological and non-pharmacological). Also included are updates on several recent and on-going clinical trials, the development of new biomarkers to aid recognition of disease and earlier intervention, and a discussion of the pharmacoeconomics of treating dementia.

Vascular Dementia

Author : Robert H. Paul
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A multidisciplinary survey of our current understanding of the biological and clinical aspects of vascular disease. The authors describe its basic mechanisms, its clinical characteristics, its pharmacological management, and the use of neuroimaging methods to investigate it. The complex relationship between VaD and AD is also fully explored with chapters on how these processes interact and how one disease may lower the threshold for clinical expression of the other.

Subcortical Vascular Dementia

Author : Rita Moretti
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Vascular dementia is one of the most common forms of mental deterioration for the elderly, second only to Alzheimer's disease. It should not be defined as a single disease, but rather as a group of syndromes that relate to different vascular mechanisms. This is one of the first books to be solely dedicated to the specific class of vascular dementia known as subcortical vascular dementia. The strict focus of the chapters give an depth review that will clarify many different aspects and give an unprecedented amount of detail about this clinical problem. Considering that vascular dementia can be prevented with early diagnosis, the research presented in this book will be important for both students and specialists of this important field.

Vascular Cognitive Impairment in Clinical Practice

Author : Lars-Olof Wahlund
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Vascular cognitive impairment is the second most common cause of dementia after Alzheimer's disease and is expected to grow in prevalence with the aging global population. The purpose of this authoritative book is to give a broad clinical perspective on vascular cognitive impairment and thus create a foundation for the implementation of good dementia care. The book focuses on pathophysiology, diagnosis, treatment and prevention. It demonstrates the underlying causes of the disorder, such as the manner in which vascular risk-factors influence the onset of vascular cognitive impairment. The concept of mixed forms of vascular dementia, Alzheimer's dementia and other vascular diseases is discussed as well as the influence of vascular changes with regard to the onset of Alzheimer's disease. The detailed section on pathophysiology will enhance clinicians' understanding of this complex disorder. Finally there is a section on pharmacological and neuropsychological treatment of cognitive and psychiatric symptoms.

Vascular Dementia

Author : John Meyer
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Vascular dementia (VAD) accounts for one-third of all dementias in today''s aging population, second only to Alzheimer's disease (DAT). Fortunately, current imaging techniques allow clinicians to view specific lesions in the brain, classify them by etiology and anatomical location, and assess changes using serial imaging, while at the same time correlating those changes with signs and symptoms of VAD or DAT. In 17 chapters, this book summarizes new concepts concerning the epidemiology, etiology, risk factors, neuropathology and pathogenesis of VAD and DAT, and mixtures of the two, and reviews their multiple causes, including microvascular and hemorrhagic lesions, and ischemic and inflammatory changes affecting both white and gray matter.

Poststroke Dementia and Imaging

Author : V. Mok
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Stroke increases the risk of dementia by approximate 2-9 times. World wide, vascular dementia (VaD) is the second commonest cause of dementia. Presence of post-stroke dementia (PSD) reduces survival among stroke survivors and increases risk of long term stroke recurrence. Varying severity levels of cognitive impairment affects functional outcome independent of physical impairment. With an ageing population, burden of PSD is expected to rise. Although PSD is prevalent, relevant to mortality and morbidity, and is potentially more preventable than Alzheimer's disease (AD), it has received less attention relative to post-stroke physical impairment or to AD. It is not until the last decade that more attention has been paid to PSD. Historically, in the late 19th century, VaD was considered to be the commonest cause of dementia. It was thought that dementia was due to a relentless strangulation of the brain's blood supply, resulting in degeneration of the brain and dementia. In the middle of the 20th century, pathological studies have begun to reveal that senile plaques and neurofibrillary tangles, rather than vascular lesions, were key findings among most of the elderly demented patients with atrophic brains. In the early 70s, VaD was thought to be uncommon and the mechanism of VaD was attributed to multiple small or large cerebral infarcts (multi-infarct dementia). In recent decades, advances of neuroimaging have enhanced greatly our understanding on VaD, its complexity far exceeds that of the concept of multi-infarct dementia. The authors aim to review the current understanding of PSD and its imaging. Poststroke dementia will first be defined. Following that, foundational issues of PSD including its classification, pathology, prevalence, and cognitive pattern will be reviewed. This sets the background for discussing the imaging aspects relevant to PSD.

Vascular cognitive impairment and dementia

Author : Sics Editore
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The average disease duration is about 5 years; the prognosis of the disease is worse than in Alzheimer’s disease (AD). The management of a memory disorder that results from cerebrovascular disease (CVD) concentrates on the causes and risk factors of CVD and on the treatment of other coexisting diseases.

Vascular Dementia

Author : Sarah R. Jacobsen
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Vascular dementia is the second most common form of dementia after Alzheimer's disease in older adults. The term refers to a group of syndromes caused by different mechanisms all resulting in vascular lesions in the brain. Early detection and accurate diagnosis are important, as vascular dementia is at least partially preventable. Risk factors for vascular dementia include hypertension, smoking, hypercholesterolemia, diabetes mellitus, and cardiovascular and cerebrovascular disease. This book presents current research from across the globe in the study of vascular dementia, including GRK2 over-expression in the context of early Alzheimer disease pathogenesis; vitamin deficiencies and vascular dementia; biofluid markers as potential markers for vascular dementia; and the epidemiology of vascular dementia.

Stroke Part II Clinical Manifestations and Pathogenesis

Author : Marc Fisher, MD
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This volume provides a comprehensive guide to the manifestations and pathogenesis involved with stroke, including advancements in research and a newfound understanding of the biochemical background of this cerebrovascular disorder. This intensive handbook is meant to give clinicians a source reference that will enable them to gain a thorough knowledge and understanding of the clinical features and management of the many neurological manifestations of stroke disorder. In addition, practitioners, clinicians, and researchers will gain a better understanding of highly studied topics, including amongst others, the medical complications associated with stroke, chapters on anterior circulation and hemorrhagic stroke syndromes, stroke related psychiatric disorders, and other rare causes of stroke disorder. * A comprehensive source that thoroughly examines the neurological manifestations of stroke * A guide to highly studied topics, including stroke complications, syndromes, and stroke related psychiatric disorders * A better understanding of the pathophysiological basis of strokes that will help practitioners better diagnose, prevent, and improve patient care

Vascular Dementia New Insights for the Healthcare Professional 2012 Edition

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Vascular Dementia: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Vascular Dementia in a compact format. The editors have built Vascular Dementia: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Vascular Dementia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Vascular Dementia: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at