Search results for: the-beta-adrenergic-receptors

The Beta Adrenergic Receptors

Author : John P. Perkins
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beta Adrenergic Receptors Advances in Research and Application 2012 Edition

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beta Adrenergic Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about beta Adrenergic Receptors in a compact format. The editors have built beta Adrenergic Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about beta Adrenergic Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of beta Adrenergic Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Beta Adrenergic Receptors

Author : Tore Bengtsson
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Characterization of the Beta Adrenergic Receptors in the Mouse Cecum

Author : Sheila J. Whittle
File Size : 61.19 MB
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Photoaffinity Labeling as a Tool to Characterize Beta adrenergic Receptors

Author : Abbas Rashidbaigi
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Adrenergic Receptors Advances in Research and Application 2011 Edition

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File Size : 58.49 MB
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Adrenergic Receptors: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Adrenergic Receptors in a compact format. The editors have built Adrenergic Receptors: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adrenergic Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adrenergic Receptors: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Caveolin 3 Overexpression Increases the Responsivity of Beta Adrenergic Receptors in Cardiac Myocytes

Author : Anna Busija
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Heart failure is a leading cause of human morbidity and mortality and has been linked to neurohormonal dysregulation of [beta]-adrenergic receptor ([beta]AR) expression and responsivity that occurs with advancing age. No overarching mechanism for this age-dependent loss in [beta]AR response has been identified. However, [beta]ARs localize to caveolae, membrane lipid raft microdomains formed by caveolin (Cav) proteins and expression of caveolin-3 (Cav3), the main Cav in caveolae of cardiac myocytes (CMs) decreases in an age-dependent manner. Therefore, aging-related reduction of Cav3 and caveolae may influence the loss of [beta]AR response, and increased Cav3 expression may alter the [beta]AR responsivity of CMs and preserve [beta]AR function into old age. The studies presented in this dissertation were designed to understand the influence of Cav3 on the [beta]AR signaling pathway. In chapter 1, we reviewed current knowledge of the biogenesis and degradation of Cavs and caveolae, described their composition and roles in compartmentalization of lipid and protein factors of cellular physiology, and identified unanswered questions informed by the state-of-the-art and human disease. In chapter 2, we tested the hypothesis that CM-specific Cav3 overexpression (Cav3 OE) would modify [beta]AR responsivity in young and aged hearts. We measured the physiological sequelae of activation of [beta]ARs in young and aged hearts with the synthetic catecholamine isoproterenol (Iso). We found significant amplification of Iso dose-induced increases in physiological contractility and relaxation of young Cav3 OE hearts, which also exhibited increased responses into old age. In chapter 3, we tested the hypothesis that Cav3 OE increases caveolar compartmentation of [beta]ARs and/or downstream effectors of the [beta]AR response and that the enhanced Cav3 OE response to Iso is mediated by [beta]1ARs or [beta]2ARs. Cav3 OE hearts did not demonstrate enhancement in targeted adenylyl cyclase- or [beta]AR isoform-specific responses. However, we discovered that [beta]AR-dependent cAMP production with Iso is subject to increased regulation by phosphodiesterase activity in Cav3 OE CMs, implicating Cav3 in differential regulation of [beta]AR signals without significant changes in protein distribution. Our findings from the studies in this dissertation support the hypothesis that Cav3 OE amplifies [beta]AR function in young hearts and preserves responsivity in aged animals. These results are the first to demonstrate that Cav3 OE is protective against loss of [beta]AR responsivity in aging hearts.

Cyclic AMP Regulation of Beta Adrenergic Receptors in the Human Fetal Lung

Author : Diane Marie Duffy
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Studies on Some New Beta Adrenergic Receptor Antagonists and the Effect of Verapamil iproveratril on Smooth Muscle Adrenergic Receptors

Author : Marian Elizabeth Bate
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Beta adrenergic Receptors and Signaling Pathways in the Heart

Author : Laura Andreasen
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Approaches Toward the Visualization of Beta adrenergic Receptors on Cultured Cells Using the Avidin biotin System

Author : Kathryn Elaine Meier
File Size : 63.79 MB
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adrenergic Beta adrenergic Receptors and Erk1 2 mediated Cardiac Hypertrophy

Author : Marie Vidal
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A Quantitative Study of the Beta adrenergic Receptors of the Chromatophore System of the Frog

Author : Samuel Edwin Taylor
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Interactions of the Beta adrenergic Receptor and the Stimulatory Guanine Nucleotide Binding Regulatory Protein in S49 Lymphoma Cells

Author : Jeffrey Raymond Jasper
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The Beta Adrenergic Receptor in Septic Shock

Author : John Sorrell Bagley
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Symposium on Beta Adrenergic Receptor Blockade

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Agonist induced Alterations in the Cellular Metabolism of Beta adrenergic Receptors in S49 Lymphoma Cells

Author : Lawrence C. Mahan
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The Effects of the Cannabinoids on the Beta adrenergic Receptor

Author : Cecilia Kiernan Hillard
File Size : 52.62 MB
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Modulation of a mammalion beta adrenergic receptor

Author : Jürgen Kleinstein
File Size : 57.47 MB
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The Ontogenesis of Beta adrenergic Receptors and Adenylate Cyclase in the Rabbit Heart

Author : William Anthony Schumacher
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