Search results for: molecular-mechanisms-of-neurotransmitter-release

Research Awards Index

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Neurotransmitter Release

Author : Hugo J. Bellen
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Begins by providing a comprehensive introduction to the features and properties of synapses. It then describes key techniques used to study neurotransmitter release, from calcium entry to exocytosis. This is followed by chapters covering the identification and function of proteins involved in neurotransmitter release, the role of phospholipids in neurosecretion, and neurotransmitter transporter proteins. Subsequent chapters concentrate on approaches to unravel the function of specific proteins in vivo using toxins that affect neurotransmitter release, giant squit axons, C. elegans, Drosophila, and mice.

Molecular Mechanisms of Neurotransmitter Release

Author : Zhao-Wen Wang
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Neurons in the nervous system organize into complex networks and their functions are precisely controlled. The most important means for neurons to communicate with each other is transmission through chemical synapses, where the release of neurotransmitters by the presynaptic nerve terminal of one neuron influences the function of a second neuron. Since the discovery of chemical neurotransmission by Otto Loewi in the 1920s, great progress has been made in our understanding of mol- ular mechanisms of neurotransmitter release. The last decade has seen an explosion of knowledge in this field. The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release. The contributors have made great efforts to write concisely but with sufficient background information, and to use figures/diagrams to present clearly key concepts or experiments. It is hoped that this book may serve as a learning tool for neuroscience students, a solid reference for neuroscientists, and a source of knowledge for people who have a general interest in neuroscience. I was fortunate to be able to gather contributions from a group of outstanding scientists. I thank them for their efforts. In particular, I want to thank Dr. Erik Jorgensen who offered valuable suggestions about the book in addition to contrib- ing an excellent chapter. I thank US National Science Foundation and National Institute of Health for their supports.

Status Epilepticus Mechanisms of Brain Damage and Treatment

Author : Antonio V. Delgado-Escueta
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Molecular and Cell Biological Aspects of Gastroenteropancreatic Neuroendocrine Tumor Disease

Author : Bertram Wiedenmann
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New molecular and cell biological approaches in the fields of neurobiology and neuroendocrinology have identified a large number of molecules that can be assigned structurally and functionally to various subcellular structures, such as secretory vesicles, the Golgi complex, the trans-Golgi network, and endosomes. It has become evident that neurons and neuroendocrine cells share many properties, such as the expression of very similar secretory vesicles and molecules, including cell adhesion molecules, neurotransmitters, hormones, neurotransmitter-receptors and hormone-receptors. Various molecules discovered and characterised in basic research have been found to be increasingly applicable for improved diagnosis and therapy of neuroendocrine tumour disease. This volume reviews current research in both basic science and clinical research from the viewpoint of its direct applicability to clinical medicine.

Molecular Mechanisms that Regulate Synaptic Efficacy at the Drosophila Neuromuscular Junction

Author : Stephanie D. Albin
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The molecular mechanisms underlying the retrograde control of presynaptic neurotransmitter release at the NMJ are not well understood. Here we describe the identification of the first known inhibitor of synaptic homeostasis. Identification of the pathways through which this inhibitor act may eventually lead to a greater understanding of the mechanisms that regulate homeostasis.

Cellular and Molecular Mechanisms Underlying Higher Neural Functions

Author : A. I. Selverston
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Despite the remarkable advances made in molecular neurobiology over the last ten years, very little progress has been made towards understanding how the brain performs higher functions: cognition, behavior, learning, and memory. One of the greatest challenges facing modern neurobiology, therefore, is the integration of data that comes from disparate levels of analysis. This volume presents the results of the Dahlem conference convened to address these issues. The purpose of the conference was to bring together brain researchers, who approach their work at different conceptual levels, to consider how their results might be synthesized into a more integrated view of how the brain works. To try and accomplish this, two specific examples were chosen: the modulation of neural circuits and the phenomena of long-term potentiation (LTP). Neuromodulation has been studied from the molecular to the behavioral level with dramatic breakthroughs at the circuit level over the last five years. Due to the possibility that it may be the cellular mechanism for certain types of learning and memory, LTP has also been studied at different levels. To assist in understanding LTP and neuromodulation at the molecular, cellular, circuit, and behavioral levels, the background papers written for the meeting are included in this volume. The conference itself was devoted to discussing LTP and neuromodulation from the perspective of each of the different levels, and the results of these discussions are presented in the group reports. Particular emphasis was given to a consideration of how the rapid progress in molecular and cellular neurobiology can be integrated into systems and behavioral neurobiology. Specific suggestions for future research in both areas were discussed thoroughly. This volume presents what is most probably the most authoritative, up-to-date assessment of LTP and neuromodulation currently available. Goal of this Dahlem Workshop: to apply new cellular and molecular concepts to the understanding of plasticity in synapses, cells, local circuits, and defined systems in the mature brain.

Molecular Mechanisms by which Synaptotagmin Regulates Calcium triggered Membrane Fusion

Author : Michael C. Chicka
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Molecular Composition and Regulation of the Fusion Pore of Calcium Triggered Exocytosis

Author : Xue Han
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Molecular Biology of the Cell

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Kokuritsu Kokkai Toshokan shoz kagaku gijutsu kankei bun kaigiroku mokuroku

Author : Kokuritsu Kokkai Toshokan (Japan)
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Peterson s Graduate Programs in the Biological Sciences 2008

Author : Peterson's
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Lists over 3,700 graduate programs in 37 disciplines in the biological sciences

Annual Report

Author : Mitsubishi Kasei Seimei Kagaku Kenkyūjo
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Bacterial Protein Toxins

Author : John Freer
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Index of Conference Proceedings

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Metabotropic Glutamate Receptors and Brain Function

Author : Flavio Moroni
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The aim of this book is to provide a broad and complete overview of research on metabotropic glutamate receptors (mGluRs). The information collected in it should contribute to the development of research in the mGluR area and provide scientists with a tool for a better understanding of this system and a broader perspective in the search for new approaches in the treatment of neurological and psychiatric disorders.

Molecular Mechanisms in General Anaesthesia

Author : M. J. Halsey
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Presynaptic Receptors and the Question of Autoregulation of Neurotransmitter Release

Author : Stanley Kalsner
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Bacterial Toxins

Author : John Stephen
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Calmodulin and Cell Functions

Author : D. Martin Watterson
File Size : 72.83 MB
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