Search results for: molecular-basis-of-human-cancer

The Molecular Basis of Human Cancer

Author : William B. Coleman
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Internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing neoplastic transformation in the breast, prostate, lung, liver, colon, and skin, and in the leukemias and lymphomas. Their discussion illuminates both recent developments and established concepts in epidemiology, molecular techniques, oncogenesis, and mutation mechanisms, as well as the chemical, viral, and physical mechanisms in cancer induction.

The Genetic Basis of Human Cancer

Author : Bert Vogelstein
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Reveals what leading experts have recently discovered about cancers caused by DNA alterations! The second edition of THE GENETICS OF CANCER, newly titled THE GENETIC BASIS OF HUMAN CANCERS, updates and informs on the most recent progress in genetic cancer research and its impact on patient care. With contributions by the foremost authorities in the field, this fascinating new edition reports on how to understand and predict tumor development - information that can enhance decision-making and advance genetic research. 2ND Edition Highlights NEW CHAPTERS: * Peutz-Jeghers syndrome * Juvenile polyposis syndrome * Tumor genome instability * Gene expression profiling in cancer * Pilomatricoma and pilomatrix carcinoma * Hereditary paragangliomas of the head and neck * Cylindromatosis * Familial cardiac myxomas and carney complex * Cancers of the oral cavity and pharynx * Genetic abnormalities in lymphoid malignancies THOROUGHLY REVISED: * Every chapter has been meticulously reviewed and revised to incorporate the most recent research and clinical findings * Includes a valuable introduction by renowned editors Vogelstein & Kinser* Features 150 MORE illustrations than the previous edition

Molecular Pathology

Author : William B. Coleman
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As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

The Molecular Basis of Cancer

Author : John Mendelsohn
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Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.

The Biological Basis of Cancer

Author : Robert G. McKinnell
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This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.

Molecular Bases of Human Diseases

Author : Elio E. Polli
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This proceedings volume contains the transactions of a special meeting held with a view to considering the most important and distinctive advances in clinical research brought about by developments in molecular biology.

DCDS B

Author :
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Molecular Basis of Breast Cancer

Author : Jose Russo
File Size : 28.53 MB
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This richly-illustrated atlas-like book provides a foundation for the biological and molecular understanding of how the mammary gland develops and how breast cancer originates. The main goal is to comprehensively review in ten chapters fundamental knowledge in breast cancer. New paradigms are described in which induction of differentiation in the mammary gland can promote prevention and cure of breast cancer. The text is extremely helpful both for clinicians treating patients and researchers looking for new avenues of development.

Molecular Diagnostics of Human Cancer

Author : Mark Furth
File Size : 26.87 MB
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Scientists and physicians share overlapping interests in fundamental cancer biology and in the potential clinical ramifications of specific mutations in cancer cells. In this volume, they present their ideas on the role of oncogenes and their protein products in human tumors, with emphasis on diagnostic applications. They also review the medical implications of discoveries concerning the genetic basis of neoplastic disease. Topics include nuclear oncogene proteins; growth factors and their receptors; activation of ras, src, and raf oncogenes; chromosomal rearrangements associated with oncogene activation; gene loss in human cancers; the identification and potential function of anti-oncogenes ; the genetic basis for the resistance of tumor cells to chemotherapeutic drugs; and DNA tumor virus oncogenes in some human cancers. Molecular Diagnosis of Human Cancer also includes technical advances, as well as data on the diagnostic and prognostic implications of particular oncogene alterations in a number of cancers, notably pediatric neuroblastoma, the myelogenous leukemias, and carcinomas of the colon, bladder, pancreas, and breast.

Research Awards Index

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Archives of Pathology Laboratory Medicine

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Cancer Research

Author :
File Size : 42.63 MB
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Subject Index of Current Extramural Research Administered by the National Cancer Institute

Author :
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Oncology hematology

Author : Martin D. Abeloff
File Size : 41.78 MB
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Molecular Pathology

Author : Ruth A. Heim
File Size : 36.98 MB
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Neoplastic Diseases

Author : C. Julian Rosenthal
File Size : 85.95 MB
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A comprehensive, yet succinct, review of neoplastic diseases with current information on their pathogenesis and therapy. Written by an outstanding team of 46 clinicians and investigators with significant teaching experience at eight medical schools and cancer institutes.

The Current Status of Gynaecology and Obstetrics Series

Author : Eng-Soon Teoh
File Size : 52.50 MB
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SV40 T Antigen in Multistep Transformation in Vitro of Human Uroepithelial Cells

Author : Chinghai Kao
File Size : 39.55 MB
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Robbins and Cotran Pathologic Basis of Disease

Author : Vinay Kumar
File Size : 40.48 MB
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Accompanying CD-ROM contains ... "over 100 clinical case studies and approximately 1,500 images ..."--Page 4 of cover.

DNA Alterations in Cancer

Author : Melanie Ehrlich
File Size : 27.69 MB
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