Search results for: heterocyclic-chemistry

Heterocyclic Chemistry

Author : Thomas Lonsdale Gilchrist
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This book provides a unique overview of the subject. The first half of Heterocyclic Chemistry covers general properties of heterocyclic compounds and general methods for their preparation. This provides the basis for understanding the chemistry of indivudal ring systems that is described in later chapters. This edition has been completely revised to reflect the changes that have occurred in the field since the publication of the second edition in 1992.

Advances in Heterocyclic Chemistry

Author : Alan R. Katritzky
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Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area—one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area - one of great importance to organic chemists, polymer chemists and many biological scientists Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties

Heterocyclic Chemistry

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Progress in Heterocyclic Chemistry

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Progress in Heterocyclic Chemistry is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new, developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 25 are all written by leading researchers in their field, and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2012. As with previous volumes in the series, Volume 25 will enable academic and industrial chemists and advanced students to keep abreast of developments in heterocyclic chemistry in a convenient way. Recognized as the premiere review of heterocyclic chemistry Contributions from leading researchers in the field Systematic survey of the important 2012 heterocyclic chemistry literature

Fundamentals of Heterocyclic Chemistry

Author : Louis D. Quin
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Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters

Heterocyclic Chemistry

Author : John A. Joule
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This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

Palladium in Heterocyclic Chemistry

Author : Jie Jack Li
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Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium chemistry to the syntheses of heterocycles has grown exponentially. These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of Palladium in Heterocyclic Chemistry is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 1. Palladium chemistry of heterocycles has its "idiosyncrasies" stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of &agr and &bgr activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called "heteroaryl Heck reaction". For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 2. A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containing natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field. We also hope this book will spur more interest and inspire ideas in such an extremely useful area. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle. The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles. Many heterocycle-containing natural products (highlighted throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry keeps readers abreast of this fast-growing field. It is also hoped that this book will stimulate more interest and inspire new ideas in this exciting field. Contains the most up-to-date developments in this fast-moving field Includes 3 new chapters Contains material from selected well-respected authors on heterocyclic chemistry

Heterocyclic Chemistry

Author : J. A. Joule
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1. Structures and main physical properties of aromatic heterocycles 1; 2. Reactivity of aromatic heterocycles 18; 3. synthesis of aromatic heterocycles 56; 4. Typical reactivity of pyridines, quinolines, and isoquinolines 64; 5. Pyridines: reactions and synthesis 72; 6. Quinolines and isoquinolines: reactions and synthesis 120; 7. Typical reactivity of pyrylium and benzopyrylium ions, pyrones and benzopyrones 146; 8. Pyryliums, 2- and 4-pyrones: reactions and synthesis 148; 9. Benzopyryliums and benzopyrones: reactions and synthesis 166; 10. Typical reactivity of the diazines: pyridazine, pyrimidine and pyrazine 185; 11. the diazines: pyridazine, pyrimidine and pyrazine: reactions and synthesis 189; 12. Typical reactivity of pyrroles, thiophenes and furans 225; 13. Pyrroles: reactions and synthesis 229; 14. Thiophenes: reactions and synthesis 259; 15. Furans: reactions and synthesis 278; 16. Reactivity of indoles, benzo[b]thiophenes, benzo[b]furans, isoindoles, benzo[c]thiophenes and isobenzofurans 301; 17. Indoles: reactions and synthesis 305; 18. Benzo[b]thiophenes and benzo[b]furans: reactions and synthesis 350; 19. Isoindoles, benzo[c]thiophenes and isobenzofurans: reactions and synthesis 360; 20. Typical reactivity of 1,3- and 1,2-azoles 367; 21. 1,3-Azoles: imidazoles, thiazoles, and oxazoles: reactions and synthesis 370; 22. 1,2-Azoles: pyrazoles, isothiazoles and isoxazoles: reactions and synthesis 394; 23. Purines: reactions and synthesis 409; 24. Heterocycles containing a ring-junction nitrogen 434; 25. Heterocycles containing more than two hetero atoms 447; 26. Saturated and partially unsaturated heterocyclic compounds: reactions and synthesis 463; 27. Appendix: answers to exercises 479.

Handbook of Heterocyclic Chemistry

Author : Alan R. Katritzky
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Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.

Heterocyclic Chemistry

Author : John A. Joule
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Heterocyclic Chemistry covers the fundamentals of heterocyclic reactivity and synthesis for second- and third-year undergraduate chemistry students. It also includes more advanced material, making the book appropriate for postgraduate courses and researchers, either at postgraduate degree level or those working with heterocyclic compounds in industry. Essential teaching material is collected in specific introductory chapters, explaining heterocyclic reactivity principle in simple terms. These chapters are augmented by detailed, systematic discussions of the chemical reactivity of particular heterocyclic systems. References to both primary literature and reviews are given throughout the text.