Search results for: drug-delivery-with-targeted-nanoparticles

Drug Delivery with Targeted Nanoparticles

Author : Yılmaz Çapan
File Size : 55.85 MB
Format : PDF, Kindle
Download : 576
Read : 700
Download »
Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Drug Delivery with Targeted Nanoparticles

Author : Taylor & Francis Group
File Size : 76.22 MB
Format : PDF, ePub, Mobi
Download : 807
Read : 1054
Download »
Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared to conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires many evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles' (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Applications of Targeted Nano Drugs and Delivery Systems

Author : Shyam Mohapatra
File Size : 51.70 MB
Format : PDF, ePub, Mobi
Download : 309
Read : 763
Download »
Applications of Targeted Nano-Drugs and Delivery Systems: Nanoscience and Nanotechnology in Drug Delivery explores the applications of Nano-drugs and their delivery systems, investigating the role they can play in key body systems and major diseases. The book explores how nanotechnology can be deployed in developing new drug delivery systems and how they enable pharmaceutical companies to reformulate existing drugs on the market, thereby extending the lifetime of products and enhancing performance by increasing effectiveness, safety and patient adherence, and ultimately reducing healthcare cost. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields. Readers will find a reference and practical source of guidance for researchers, students and scientists working in the fields of nanotechnology, materials science, and technology and biomedical science. Enables readers from different fields to access recent research and protocols across traditional boundaries Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques Explores the applications of Nano-drugs and their delivery systems, investigating the role they can play in key body systems and major disease types

Design of Optimized Peptide targeted Nanoparticles for Accomplishment of Selective Drug Delivery to Cancer Cells and Development of Inhibitors for Food Allergic Reactions

Author : Baksun Kim
File Size : 39.21 MB
Format : PDF, ePub, Docs
Download : 160
Read : 310
Download »

Nanoparticles for Drug Delivery

Author : K. S. Joshy
File Size : 69.18 MB
Format : PDF, ePub, Docs
Download : 166
Read : 898
Download »
This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

Progress Toward a Colon Targeting Nanoparticle Based Drug Delivery System

Author : Xiao Yu
File Size : 73.5 MB
Format : PDF, Mobi
Download : 597
Read : 459
Download »
Hydrophobic drug paclitaxel nanoparticles (PAX NPs) and pH sensitive hydrogels were prepared in this study to build a colon targeting nanoparticle based drug delivery system for oral administration. Negative charged PAX NPs at the size of 110 +/- 10 nm were fabricated, characterized and then encapsulated in synthetic / biomacromolecule shell chitosan, dextran-sulfate using a layer by layer (LbL) self-assembly technique. Surface modifications were performed by covalently conjugating with poly (ethylene glycol) (H2N-PEG-carboxymethyl, Mw 3400) and fluorescence labeled wheat germ agglutinin (F-WGA), so as to build a biocompatible and targeted drug delivery system. Extended release of drug paclitaxel can be realized by adding more polyelectrolyte layers in the shell. High cell viability with PEG conjugated and high binding capacities of WGA modified nanoparticles with Caco-2 cells were observed. Preliminary study on stability of the nanoparticles in suspension at different pH was also performed. Two dextran based pH sensitive and enzyme degradable hydrogels: dextran maleic acid (Dex-MA), and glycidyl methacrylated dextran (Dex-GMA) were synthesized for oral delivery of nanoparticles. Hydrogels of both kinds were stable in simulated gastric fluid, but were prone to swelling and degradation in the presence or absence of enzyme dextranase in simulated intestinal fluid. The release profiles of nanoparticles could be tuned from 5 hr to 24 hr periods of time with more than 85% of the nanoparticle released in the simulated intestinal fluid. The release of PAX NPs was completed with longer time periods (45 hr-120 hr). Two possible release mechanisms were discussed for Dex-MA and Dex-GMA-co-AA hydrogels respectively: degradation controlled, and diffusion controlled. These biodegradable hydrogels, which can release nanoparticles depending on pH changes, together with the biocompatible and targeted nanoparticles, may be suitable as a potential colon targeting system for oral delivery of drug nanoparticles.

Drug Delivery with Targeted Nanoparticles

Author : Yılmaz Çapan
File Size : 38.77 MB
Format : PDF, ePub, Docs
Download : 315
Read : 565
Download »
Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Targeted Drug Delivery Concepts and Design

Author : Padma V. Devarajan
File Size : 31.54 MB
Format : PDF, Docs
Download : 748
Read : 1188
Download »
This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Nanobiotechnology in Diagnosis Drug Delivery and Treatment

Author : Mahendra Rai
File Size : 57.55 MB
Format : PDF, Docs
Download : 451
Read : 494
Download »
Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Nanotechnology Based Targeted Drug Delivery Systems for Lung Cancer

Author : Prashant Kesharwani
File Size : 66.60 MB
Format : PDF, ePub
Download : 447
Read : 775
Download »
Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Functionalization of Nanocarriers for Efficient Combination Drug Delivery

Author : Che-Ming Jack Hu
File Size : 43.75 MB
Format : PDF, ePub, Docs
Download : 806
Read : 1205
Download »
Therapeutic Nanoparticles have shown significant impact in the field of medicine, particularly in anticancer drug delivery. Prolonged circulation time, functionalization with tumor-targeting ligands, and encapsulation of multiple drug types are among the key features of nanoparticles that make them desirable anticancer drug carriers. This dissertation will focus on these three major features of therapeutic nanoparticles and provide novel improvements in these areas. The first area of research is multi-drug coencapsulation, where precise control over drug-to-drug ratio has a major impact on the particles' therapeutic efficacy. A drug-polymer conjugate system is used to overcome the intrinsic differences in the physicochemical properties of different drug molecules. By adapting metal alkoxide chemistry, we synthesize highly hydrophobic drug-poly-l-lactide (drug-PLA) conjugates, of which the polymer has the same chain length while the drug may differ. These drug-polymer conjugates are then encapsulated into lipid-coated polymeric nanoparticles through a single-step nanoprecipitation method. Using doxorubicin (DOX) and camptothecin (CPT) as two model chemotherapy drugs, various ratios of DOX-PLA and CPT-PLA conjugates are loaded into the nanoparticles with over 90% loading efficiency. The resulting nanoparticles are uniform in size, size distribution and surface charge. The loading yield of DOX and CPT in the particles can be precisely controlled by simply adjusting the DOX-PLA:CPT-PLA molar ratio. Cellular cytotoxicity results show that the dual-drug loaded nanoparticles are superior to the corresponding cocktail mixtures of single-drug loaded nanoparticles. This dual-drug delivery approach offers a solution to the long-standing challenge in ratiometric control over the loading of different types of drugs onto the same drug delivery vehicle. The second area is nanoparticle functionalization for tumor-targeted delivery. we synthesize anti-CEA half-antibody conjugated lipid-polymer hybrid nanoparticles and characterize their ligand conjugation yields, physicochemical properties, and targeting ability against pancreatic cancer cells. Under the same drug loading, the half-antibody targeted nanoparticles show enhanced cancer killing effect compared to the corresponding non-targeted nanoparticles. The half-antibody approach offers the advantage of reduced ligand size, site-specific conjugation, and easy accessibility over existing functionalization approaches. The third area of research presented herein is a novel nature-inspired approach to camouflage nanoparticles for long systemic circulation. A top-down approach in coating biodegradable polymeric nanoparticles with natural erythrocyte membranes is reported. The structure, size and surface zeta potential, and protein contents of the erythrocyte membrane-coated nanoparticles were verified using transmission electron microscopy, dynamic light scattering, and gel electrophoresis respectively. Mice injections with fluorophore-loaded nanoparticles revealed superior circulation half-life by the erythrocyte-mimicking nanoparticles as compared to control particles coated with the state-of-the-art synthetic stealth materials. Biodistribution study revealed significant particle retention in the blood 72 hours following the particle injection. The translocation of natural cellular membranes, their associated proteins and the corresponding functionalities to the surface of synthetic particles represents a novel approach in nanoparticle functionalization. The developments on these three areas are compatible with one another and could be integrated as one multifunctional nanoparticle platform. Each of these features aims to target a distinctive barrier in cancer drug delivery.

Silica coated Magnetic Nanoparticles

Author : Mariela A. Agotegaray
File Size : 81.25 MB
Format : PDF, Docs
Download : 992
Read : 1217
Download »
This brief offers a comprehensive discussion of magnetic targeted drug delivery of silica-coated nanodevices. Focusing on the latest trend in pharmaceutical applications of these nanodevices, a multidisciplinary overview is displayed, from synthesis and design to pharmacokenetics, biodistribution and toxicology. Chapters include design of silica-coated magnetic nanodevices; techniques for drug loading with features applicable to biological systems; synthesis, characterization and the assessment of biomedical issues with both in vitro and in vivo experiments. Applications in the treatment of different localized diseases are also addressed in order to present the potential use of these nanosystems as global, commercially available therapeutics.

Surface Modification of Nanoparticles for Targeted Drug Delivery

Author : Yashwant V Pathak
File Size : 57.72 MB
Format : PDF, Mobi
Download : 336
Read : 809
Download »
This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Drug Delivery

Author : Binghe Wang
File Size : 65.69 MB
Format : PDF, ePub, Mobi
Download : 122
Read : 1254
Download »
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Nanotechnology Based Approaches for Targeting and Delivery of Drugs and Genes

Author : Vijay Mishra
File Size : 61.54 MB
Format : PDF, ePub, Mobi
Download : 772
Read : 1165
Download »
Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

Fundamentals of Drug Delivery

Author : Heather A. E. Benson
File Size : 79.58 MB
Format : PDF, ePub, Docs
Download : 238
Read : 664
Download »
A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Advanced Drug Delivery

Author : Ashim Mitra
File Size : 79.8 MB
Format : PDF
Download : 911
Read : 421
Download »
Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to datewith the state of the science, presenting the basics, formulationstrategies, and therapeutic applications of advanced drug delivery.The book demonstrates how core concepts of pharmaceutical sciences,chemistry, and molecular biology can be combined and applied inorder to spark novel ideas to design and develop advanced drugdelivery systems for the treatment of a broad range of humandiseases. Advanced Drug Delivery features contributions from aninternational team of pharmaceutical scientists. Chapters reflect athorough review and analysis of the literature as well as theauthors' firsthand experience developing drug delivery systems. Thebook is divided into four parts: Part I, Introduction and Basics of Advanced DrugDelivery, explores physiological barriers, stability,transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offerstested and proven strategies for advanced delivery of both smallmolecules and macromolecules Part III, Translational Research of Advanced DrugDelivery, focuses on regulatory considerations andtranslational applications of advanced drug delivery systems forthe treatment of cardiovascular diseases, cancer, sexuallytransmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery inEmerging Research Areas, examines stem cell research,cell-based therapeutics, tissue engineering, and molecularimaging Each chapter provides objectives and assessment questions tohelp readers grasp key concepts and assess their knowledge as theyprogress through the book. Advanced Drug Delivery is recommended for graduates andupper-level undergraduates in the pharmaceutical sciences who needa solid foundation in the basics. It is also recommended forpharmaceutical professionals who want to take advantage of new andemerging applications in advanced drug delivery systems.

Magnetic Nanoparticles for Targeted and Triggered Drug Delivery

Author : Freddy Wang
File Size : 39.53 MB
Format : PDF
Download : 494
Read : 178
Download »

Targeted and Nanoparticle Therapies for Lung Diseases

Author : Ruchit Trivedi
File Size : 37.43 MB
Format : PDF, Docs
Download : 246
Read : 644
Download »
Drug delivery to the lungs is difficult to achieve and conventional approaches like intravenous and oral administration of drugs do not effectively deliver drugs to the lungs. The inhalation route of administration provides a way to deliver the drugs locally, thereby increasing their efficacy. However, there are several problems associated with inhalation delivery like rapid clearance from the lung, uptake by non-relevant cell types within the lung, leading to side effects, and difficulty of formulation. Apart from these routes and their difficulties, optimization of drug delivery is required for different type of drugs like proteins, siRNAs, and small molecules. Hence, efficient drug delivery to the lung is an unmet need for the treatment of lung diseases. The objective of this research was to design and implement novel targeted drug delivery strategies to deliver proteins, siRNAs, and small molecules (pirfenidone) for the treatment of lung diseases. We evaluated efficacy of a fusion protein of tumstatin in vitro in proliferation, invasion, and tube formation assays, and in vivo in a xenograft model of lung cancer upon intravenous administration and comparedit with its parent molecule tumstatin. We found that transferrin-tumstatin was superior to tumstatin in all the assays. siRNA delivery to the lung is challenging, and to achieve effective delivery of siRNA to the lungs, we prepared novel targeted nanoparticles encapsulating CXCL1 siRNA. CXCL1 siRNA was used as a model siRNA to treat acute lung injury in mice which reflects human acute respiratory distress syndrome (ARDS). We evaluated the biodistribution and efficacy of these nanoparticles in a bleomycin induced ARDS mouse model. We found that functionalized nanoparticles were superior in targeting the lungs as well as more efficacious in treating ARDS when compared to non-functionalized nanoparticles and naked siRNA. For small molecule delivery, we developed an inhalation route of administration. For inhaled drugs, it is essential to target them to relevant cells. First, we determined the optimum size of nanoparticles to target various cells within the lung and then used optimally sized nanoparticles to treat a mouse model of idiopathic pulmonary fibrosis (IPF) using pirfenidone as a model small molecule. We found that 200 nm nanoparticles were superior at targeting epithelial cells compared to 20 nm and 2000 nm nanoparticles. Nanoparticles sized approximately 200 nm loaded with pirfenidone were more effective in retaining the drug within the lung up to 1 week compared to pirfenidone solution and they were more efficacious in treating pulmonary fibrosis in a mouse model compared to pirfenidone solution.

Stimuli Responsive Magnetic Nanoparticle Carrier for Targeted Drug Delivery

Author : Rajesh Venkatasubramanian
File Size : 38.36 MB
Format : PDF, Kindle
Download : 249
Read : 449
Download »