The aim of this book is to provide a comprehensive overview of current concepts in pathogenesis, diagnosis and treatments of diabetic retinopathy. It provides a collection of topics written by excellent authors, covering discussions on advances in understanding of pathophysiology, immunological factors and emerging concepts, relating to clinical aspects and treatment strategies. The contents of the book will not only provide a resource for our knowledge but also improve diagnosis and treatment options for those patients who suffer vision loss due to diabetic retinopathy.

This volume sets the stage for clinical experts working with diabetic patients as well as for researchers by describing the clinical presentations of retinopathy and their anatomical and functional correlates. It reviews currently available experimental models in animals. The impact of retinal pericytes, neuroglia and, specifically, Mller cells are discussed in detail. The volume addresses a variety of current scientific discussions about mechanisms of damage such as growth factors and the VEGF/PEDF balance in the diabetic eye, the ocular renin-angiotensin system, and leukocyte interactions with the microvasculature among others. Stem and progenitor cells in the retina are discussed as potential directions for future investigation. The final chapters return to emerging clinical aspects, including current approaches to retinopathy as a predictor of cardiovascular risk and how knowledge can be translated from bench to bedside. Bridging a widening gap in medical research between basic scientists, who may lose sight of the clinical presentations, and clinical researchers, who may grow unaware of the limits of experimental models, this volume serves as a reference platform for endocrinologists, diabetologists, ophthalmologists, as well as for scientists involved in clinical and basic research in diabetic retinopathy and other vascular complications of diabetes.

The "bible" on diabetes mellitus is now in its Fourteenth Edition—thoroughly revised and updated by more than 80 noted experts from the Joslin Diabetes Center and other leading institutions worldwide. This edition includes a new eleven-chapter section on hormone action and the regulation of metabolism. The section on definition and pathogenesis now includes chapters on genetics, diabetes in Asia and Africa, and diabetes in U.S. minority groups. Other new chapters cover retinopathy, cardiovascular disease, wound healing, and treatment of women with diabetes. All of the Fourteenth Edition's figures have been completely updated.

Diabetic Retinopathy is a concise guide to the condition caused by complications of diabetes, which can eventually lead to blindness. The book is edited by a team of experts from the Italian Macular Centre in Rome, led by Prof Bruno Lumbroso. Divided into ten chapters, the book begins with basic information on diabetes and diabetic retinopathy. Further chapters demonstrate how to read and interpret different forms of imaging, including fluorescein angiography, cross-section OCT, and ‘en-face’ OCT. Information on the use of the most recent OCT angiography imaging techniques brings this book fully up to date. 73 full colour images and illustrations enhance the text, which highlights the importance of clinical imaging in everyday treatment of diabetic retinopathy. Diabetic Retinopathy is an essential guide to imaging and treatment for ophthalmologists and optometrists. Key Points Concise guide to diabetic retinopathy, including imaging modalities and treatment Up to date information on new imaging techniques Full colour images and illustrations throughout Expert editorial team from Italian Macular Centre, Rome

Diabetic Retinopathy: The Essentials is written for general ophthalmologists and optometrists as well as family practitioners, diabetologists, and internists who encounter diabetic patients on a daily basis. It focuses on the diagnosis and management of diabetic retinopathy from the point of view of the retinal specialist. The book begins with the epidemiology, anatomy, and pathophysiology of diabetic retinopathy, and then covers important topics such as classification issues, diagnostic testing, examination techniques, new treatment modalities, patient management, indications for vitrectomy, pregnancy concerns, and informed consent. Coverage includes both general medical issues in diabetes and specifically ophthalmologic concerns. Features include more than 200 full-color photographs, case studies, and algorithms for patient management. A companion website includes the full text online and an image bank.

Contains information from the Diabetic Retinopathy Clinical Research network not to be found in other published works Evidence-based approach includes material labeled with level of supporting evidence and many clinical examples Includes discussions of area of controversy

This book addresses diabetic retinopathy, an eye disease that remains one of the main causes of vision loss if not diagnosed and managed properly. It aims to cover the entire spectrum of the disease by describing its clinical identification and characterization, pathophysiology, epidemiology, and medical and surgical management. Diabetic Retinopathy also offers a complete overview of the present understanding of diabetic retinopathy, covering current practice but also including original contributions that offer novel perspectives for looking at and addressing this disease. The author has dedicated his lifetime to the study of diabetic retinal disease and has organized this book around his personal experience but at the same time giving the necessary information for updated management of diabetic retinopathy. Diabetic Retinopathy will be especially useful for postgraduate students in diabetology, retina specialists and researchers.

A well-illustrated and comprehensive analysis of the treatment of diabetic retinopathy, this book covers current treatment options and guidelines, whilst also providing a detailed discussion of emerging therapeutic targets. Existing therapeutic options are covered in depth, with a major focus on anti-vascular endothelial growth factor drugs and sustained release corticosteroids, including a review of trial results supporting current treatment guidelines. The use of agents off-label is also discussed. Controversial topics are discussed in detail with an emphasis on helping the reader make informed decisions, particularly when treating patients for which several treatment approaches may be appropriate because trial data does not clearly define the best option. Emerging therapeutic areas are evaluated, as work continues to identify agents that produce superior morphologic responses and visual acuity gains by targeting other molecules that contribute to diabetic retinopathy. Promising new drugs, targets and delivery systems are identified, and their development analysed.

Another title in the award winning ‘Practical Manual’ series from Wiley-Blackwell, following on from Edmonds, Foster and Sanders‘ A Practical Manual of Diabetic Foot Care – winner of the British Medical Association’s Medical Book of the Year Award 2004. This practical clinical manual covers the diagnosis, treatment and long-term management of eye problems in people with diabetes, with a strong emphasis on the importance of early diagnosis. Edited and authored by world-renowned experts from leading centres, A Practical Manual of Diabetic Retinopathy Management presents evidence-based guidance relevant for a global audience. High quality photographs uniquely illustrate the lesions that occur in diabetic retinopathy and diagrams show the surgical techniques involved in vitreoretinal surgery for advanced stages of the disease Numerous real life case histories demonstrate the scenarios that one is likely to come across in a clinic treating patients with diabetic retinopathy The best colour guide to the spectrum of changes that occur in diabetic retinopathy This bookis a richly illustrated manual on the management of all stages of diabetic retinopathy, ideal for diabetologists, general endocrinologists who see patients with diabetes, retinal screeners, ophthalmologists and any other healthcare professionals involved in the care and management of diabetes.