Search results for: diabetes-and-diabetic-complications

Diabetes and Diabetic Complications

Author : Randhir Singh Dahiya
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"Diabetes mellitus is one of the major causes of morbidity and mortality in the modern world. Persistent hyperglycaemia is responsible for several complications of diabetes, such as diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, diabetic cardiomyopathy, diabetic autonomic neuropathy, diabetic ketoacidosis, diabetic foot ulcer, gestational diabetes, and diabetic mastopathy. With the advancement of technology, several new drugs have been developed for treatment of diabetes and diabetic complications. Moreover, alternative and complementary medicines have also been employed to manage diabetes and its associated complications. Despite the availability of a plethora of therapeutic agents, the management of diabetes and diabetic complications is an uphill battle associated with several limitations. Various leading research groups across the world are investing billions of dollars to develop impeccable solutions for the treatment of diabetes and diabetic complications. This book focuses on the understanding of recent advancements in the pathogenesis of diabetes and diabetic complications, the molecular basis of the disease and recent advancements in diabetic treatment. The chapters are specifically dedicated to different complications associated with diabetes. Moreover, recent advances in treatments and medications in clinical trials for these complications are explained. Some chapters are dedicated to the use of herbal medicines, alternative and complementary therapy and personalized medicines. Furthermore, the role of epigenetics in diabetic complications is described, as well as the role of antidiabetic drugs and their interactions. Due to its widespread prevalence, diabetes is presently considered a pandemic. This book provides contemporary information to researchers and health care practitioners about diabetes and diabetic complications, which may pave the way for designing new strategies to manage diabetes and diabetic complications. Moreover, the insights on alternative and complementary medicines will help in providing a background for inclusion of these medicines as an important therapeutic option for treatment of diabetes"--

Diabetes

Author : Kenneth M. Shaw
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Diabetes is one of the leading causes of morbidity and mortality worldwide. Major complications include nephropathy, neuropathy, retinopathy and heart disease, which affect thousands of diabetics every year. The prevention and treatment of such complications encompass pharmacological, surgical and educational approaches, all of which need to be coordinated for optimal management of people with diabetes. This user-friendly new edition of Diabetes - Chronic Complications (previously called Diabetic Complications) has been completely revised and updated to reflect the rapid developments currently taking place in the field. Each chapter describes the epidemiology, aetiology and management of a particular complication and discusses the organisation and delivery of care. Includes all the major chronic complications of diabetes Presents a practical approach to the treatment of diabetes complications Written by world’s leading experts in the field Features algorithms for screening and treatment of diabetes complications

Complications of Diabetes

Author : Rajeev Chawla
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Complications of Diabetes is a concise reference introducing clinicians to the possible complications with diabetes. It stresses the need for early detection and covers all complications occurring in different parts of the body. Beginning with an overview of acute and chronic complications of diabetes, separate chapters discuss renal complications, ocular complications, foot complications, diabetes and coronary artery disease and diabetes and cerebrovascular disease.

Diabetes

Author : Kenneth M. Shaw
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This edition of Diabetes: Chronic Complications provides both the experienced and trainee endocrinologist with easy-to-read, up-to-date practical guidance on the management of the many complications that can result from the onset of diabetes, such as kidney failure, cardiovascular disease, retinal failure, and cerebrovascular disease. Reflecting the rapid developments currently taking place in the field, the second edition introduces a brand-new section on liver complications in diabetes, additional material on mental health complications in the section on diabetes and the brain, coverage of dyslipidaemia and hypertension in the section on diabetes and the heart, five MCQ's in each section to help improve clinical skills, and a case study and key points summary box in every chapter.

Fast Facts Diabetes Mellitus

Author : Ian N. Scobie
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Now in its fifth edition, 'Fast Facts: Diabetes Mellitus' continues to grow in popularity as essential reading for all healthcare professionals. As well as providing a practical approach to the causes and clinical manifestations of types 1 and 2 diabetes, it is packed with information on early detection, and comprehensive details of the latest drug therapies, insulin regimens, delivery methods and injection sites. Importantly, this effective handbook provides simple clear messages to give to your patients to maximize their self-management skills. All healthcare professionals can have a significant life-altering effect on the health outcomes and quality of life of people living with diabetes, and this is the ideal update on current practice for primary care providers, specialist nurses, students of medicine and nursing, educators, pharmacists, allied health professionals and doctors of all specialties in training, as well as specialists in other fields who regularly see patients with diabetes. And one for your patients too. "The public increasingly desire being kept informed and abreast of diabetes care. I actively encourage it, since an informed and engaged patient is more easily kept within treatment targets," says Dr Katherine Samaras (author). So we encourage you to make your patients well-informed active partners in their diabetes care by sharing this highly readable book with them. Contents: • Epidemiology • Diagnosis • Type 1 diabetes mellitus • Type 2 diabetes mellitus • Other types of diabetes mellitus • Treatment of type 1 diabetes mellitus • Treatment of type 2 diabetes mellitus • Diet and physical activity • Complications and mental health considerations • Hypoglycemia • Diabetic ketoacidosis and hyperosmolar hyperglycemic state • Pregnancy and diabetes • Useful resources

Diabetes and Diabetic Complications in Key World Markets

Author : Kenneth G. Krul
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Diabetes Sourcebook

Author : Karen Bellenir
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Basic Information about Insulin-Dependent and Noninsulin-Dependent Diabetes Mellitus, Gestational Diabetes, and Diabetic Complications, Symptoms, Treatment, and Research Results, Including Statistics on Prevalence, Morbidity, and Mortality, along with Source Listings for Further Help and Information

Antioxidants in Diabetes Management

Author : Peter Rosen
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This volume summarizes current understanding of the pathogenic role of oxidative stress in the onset and progression of diabetes and its complications, and presents results of studies aimed at regulating oxidatively induced complications through the use of antioxidants. Examines the presence of impaired microcirculation, capillary hypoxia, and ischemia syndrome in diabetic complications! Designed to stimulate scientific discussion and curiosity about the causes of diabetes, with contributions from nearly 65 clinicians and researchers who cite more than 1300 sources, Antioxidants in Diabetes Management focuses on stringent control of hyperglycemia to prevent or modify onset and progression promotes the development of intervention strategies because of the therapeutic limitations of hypoglycemic therapy emphasizes the potential synergistic effects of an interlinked antioxidant network investigates the controversy surrounding the significance of oxidative stress markers in diabetes highlights oxidative stress and antioxidant treatment in animal models for juvenile and adult onset diabetes explores the hypothesis that ischemic reperfusion is the primary cause of diabetic polyneuropathy links protein kinase C activation to the development of diabetic vascular complications and the effectiveness of vitamin E in preventing these abnormalities spotlights recent clinical trials of therapeutic effects of antioxidants to reduce insulin resistance and much more! Illustrating the therapeutic potential of antioxidants for the treatment of diabetes, Antioxidants in Diabetes Management is an unparalleled reference for endocrinologists, nutritionists and dietitians, cell biologists and biochemists, cardiologists, pathologists, and graduate and medical school students in these disciplines.

Diabetes and Its Management

Author : Peter J. Watkins
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Highly Commended in the 2004 BMA Medical Book Competition (Endocrinology) Judges’ summary: “Beautifully and clearly written to appeal to all levels of healthcare professional knowledge. A wealth of practical experience is freely donated to the reader in a friendly and accessible way. Each section is easily found and any member of the team could care for a patient with that particular problem to a high standard with this book in their hand. I would unhesitatingly recommend to all diabetes doctors – both senior and junior, and every diabetes unit should have a copy. This new edition is excellent and should be considered for an award.” Diabetes and its Management, Sixth Edition, continues to provide a practical clinical guide to the management of patients with diabetes. The author team has been expanded and now also includes a Nurse Practitioner specialising in diabetes to provide the nursing perspective. It is a concise manual that distils the essential recent developments into practical advice.

Diabetic Complications

Author : Domenico Andreani
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The prevention and treatment of diabetic complications is now recognised as one of the most significant issues in the successful management of diabetes. Recent research has resulted in considerable improvements in the quality of life of longterm diabetic patients, but the subject remains a major challenge in modern diabetology. It is therefore important constantly to review and reappraise the achievements of past research, discuss current trends, and re-evaluate future goals.

Diabetes Mellitus

Author : Oluwafemi Oguntibeju
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The fundamental treatment and management goals in diabetes mellitus are to control and normalize blood glucose levels and to prevent diabetic complications. It also includes maintaining normal growth and development and normal body weight. Proper diet, regular exercise, weight control and different therapeutic agents are the mainstays of diabetic care and management. Weight reduction and exercise have been shown to improve tissue sensitivity to insulin and allow its proper use by target tissues. It is obvious that medical management and goals of therapy for diabetes mellitus have changed since the publication of the Diabetes Control and Complications Trial in 1993. Recent studies have shown that the risk of developing retinopathy can decrease by 76% in properly managed diabetic patients when compared to control group and that clinical and laboratory signs and symptoms of nephropathy and neuropathy can also decrease by 54 to 60%. Modern approaches to the management of diabetes mellitus embrace holistic options and this book addressed various approaches in the management of diabetes mellitus.

Chronic Complications in Diabetes

Author : Anders A F Sima
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Individual volumes in the series Frontiers in Animal Diabetes Research provide basic researchers as well as clinical investigators with in-depth coverage of basic experimental diabetes research. Each volume will be topic oriented with timely and liberally referenced reviews. The series will provide a valuable reference source for basic researchers

Diabetes

Author : Yongsoo Park
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Diabetic neuropathy is a serious complication in 60–70% of diabetic patients involving both type 2 and type 1. Several signaling pathways have been assumed to contribute to its development, including increased activation of the polyol pathway, oxidative stress, advanced glycation end product (AGE) formation, nerve hypoxia/ischemia, activation of protein kinase C and reduction of nerve growth factors. As a central integrating mechanism, overproduction of reactive oxygen species in peripheral nerves leads to oxidative stress, mitochondrial dysfunction, neuronal damage and finally apoptosis. Oxidative stress results in an increase in substrate for AGEs and in precursors of glycoxidation and lipoxidation products, and accelerates the free radical formation that may be accompanied by or caused by a deficiency of antioxidant and detoxification pathways. Oxidative stress is accompanied by the activation of the NF-κB, and then mitogen-activated protein kinases (MAPK) in Schwann cells as well as in neurons, which will lead to the activation of various inflammatory cytokines. Therefore, antioxidant treatment may improve neuronal repair in patients with diabetic neuropathy. However, the true mechanisms by which increased oxidative stress affects downstream signaling mechanisms, and how this results in the development of diabetic neuropathy have not yet been thoroughly studied. Neither is it known whether antioxidant supplementation could help the damaged neurons to regenerate, and thus enable patients with diabetic neuropathy to overcome this devastating, life-threatening situation.

Diabetic Complications

Author : M. James C. Crabbe
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Childhood and Adolescent Diabetes

Author : Simon Court
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Written by individuals who between them currently share in the care of over 1,000 young diabetics, the book provides answers to the questions asked by parents and practical solutions to the problems confronting children, young people and their parents. In addition, suggestions and solutions are provided for professionals who are developing packages of care, audit systems, standards and activities outside the diabetic clinic. Special attention is given to the role of the paediatric diabetes nurse specialist and the purpose of the children's diabetic clinic, with particular strategies of care and examples of documentation being provided.

Diabetic Cardiomyopathy

Author : Belma Turan
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Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double within the next 20 years. Among the 3.8 million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy. Twenty five articles in this book are organized in three sections. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural alterations in heart. In the second section, several cellular and molecular mechanisms are discussed indicating that diabetic cardiomyopathy is a multifactorial and complex problem. The third section discusses the prevention and treatment of diabetes using appropriate diet, proper supplements including antioxidants, angiotensin inhibitors and some other drugs. All in all, this book discusses the diverse mechanisms of diabetic cardiomyopathy with some information on new therapeutic approaches for finding solutions to prevent or reverse the development of cardiac dysfunction.

Diabetic Complications

Author : Kenneth Shaw
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The probability of diabetic complications and their progression has been greatly reduced by the implementation of modern treatment regimens, better monitoring of control and improved education. Diabetic Complications comprehensively reviews diabetes care by outlining the nature of the complication, how susceptibility and risk can be identified, the importance of screening during the early stages and the manner in which appropriate investigation and management should be undertaken. Chapters are written by experienced clinicians with the emphasis on multidisciplinary care, both primary and secondary, and include: Diabetic retinopathy Diabetic renal disease Diabetic neuropathy Macrovascular disease in diabetes mellitus Nursing perspectives This volume is essential reading for all those working with people who have diabetes, whether doctors, nurse specialists or allied health workers.

Microvascular Complications of Diabetes ECAB

Author : V Seshiah
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The pathogenesis of microvascular complications is complex and multifactorial. Yet, hyperglycemia emerges as the most important single cause, which has been proved by the Diabetes Control and Complications Trial (DCCT). Thus, the importance of protecting the body from hyperglycemia cannot be overstated; the direct and indirect effects on the human vascular tree are the major source of morbidity and mortality in both type 1 and type 2 diabetes. Generally, the injurious effects of hyperglycemia are separated into macrovascular complications (coronary artery disease, peripheral arterial disease, and stroke) and microvascular complications (diabetic nephropathy, neuropathy, and retinopathy). It is important for physicians to understand the relationship between diabetes and vascular disease because the prevalence of diabetes continues to increase in our country, and the clinical requirements for primary and secondary prevention of these complications are also expanding.

Vascular Complications of Diabetes

Author : Richard Donnelly
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Diabetes has reached epidemic proportions, and the cardiovascular complications of diabetes are life-threatening and disabling. This book is unique in providing a simple explanation of the biochemical role of PKC in diabetes complications, which allows clinicians to understand why PKC inhibitors (in development) are an exciting prospect for future treatment to slow progression of eye & foot complications. New features of this Second Edition include: Updated throughout to reflect the impact of recent major clinical trials on current clinical practice Includes a major new section on diabetic neuropathy Revised section on diabetic retinopathy Each chapter is short and succinct, focusing on ‘best practice’. There are key learning points at the end of each chapter, with numerous helpful tables, figures and clinical images.

New Strategies to Advance Pre Diabetes Care Integrative Approach by PPPM

Author : Mahmood S. Mozaffari
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This book is intended to provide up-to-date and emerging information in the field of diabetes mellitus with a focus on preventive, predictive and personalized medicine.