Search results for: channelopathies

Channelopathies of the Nervous System

Author : Michael Rose
File Size : 47.57 MB
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* A unique reference focusing on the rapidly developing field of channelopathies of common neurological disorders * Written specifically for the clinical neurologist and neuroscientist * It reviews the underlying scientific principles of ion channel function and the current research and its clinical applications * A timely and unique reference focusing on the rapidly developing field of channelopathies of the nervous system from brain to muscle * Written specifically for the clinical neurologist and neuroscientist * Reviews the scientific principles of ion channel function and the clinical manifestations of the ion channel dysfunction

Wiley Encyclopedia of Chemical Biology Volume 4

Author : Tadhg P. Begley
File Size : 85.7 MB
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The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Environmental Health Perspectives

Author :
File Size : 85.75 MB
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Channelopathies

Author : F. Lehmann-Horn
File Size : 84.32 MB
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This book describes human hereditary ion channel diseases of voltage- and ligand-gated ion channels covering the diverse fields of medicine myology, neurology, cardiology, and nephrology requiring a wide and interdisciplinary readership. Interesting parallels in pathogenetic mechanisms of disease are especially emphasized to interest even highly specialized readers in entities outside of their fields. Each author has written an objective overview of his or her particular subject in a way that should allow the reader within a short period of time to obtain a comprehensive picture of the present state of art.

Channelopathies in Heart Disease

Author : Dierk Thomas
File Size : 39.74 MB
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This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field. The book is organized in three parts: part I treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels, part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications. The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.

Motor Disorders

Author : David S. Younger
File Size : 30.21 MB
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Updated and expanded for its Second Edition, this volume offers practical guidance in the diagnosis and treatment of motor disorders. The book brings together, in one convenient source, the entire spectrum of motor disorders caused by various etiologies. Seventeen new chapters cover vertigo and vestibular disorders; laryngeal motor disorders; facioscapulohumeral muscular dystrophy; myalgia, fibromyalgia, fasciculation, and cramps; plexus disorders; entrapment neuropathies; the diabetic neuropathies; Guillain-Barr� syndrome; rupture of an intervertebral disc and related spinal disorders; vitamin B12 (cobalamin) deficiency; adult normal pressure hydrocephalus; motor aspects of stroke; motor sequelae of dementia; motor sequelae of epilepsy; central nervous system vasculitis; traumatic brain injury; and motor disorders associated with cerebral palsy.

New Insights in Skeletal Muscle Channelopathies A Rapidly Expanding Field

Author : Lorenzo Maggi
File Size : 49.28 MB
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Jean-François Desaphy is a co-inventor, with no personal financial interest, of a European patent assigned to a pharmaceutical company regarding the use of a company drug in myotonic syndromes.

Sudden Cardiac Death and Channelopathies

Author : Giannis G. Baltogiannis
File Size : 73.42 MB
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Wiley Encyclopedia of Chemical Biology Volume 2

Author : Tadhg P. Begley
File Size : 45.92 MB
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The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

How Soon Will We Prevent Neurodisability in Childhood

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File Size : 60.35 MB
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Supplements to Clinical Neurophysiology

Author :
File Size : 78.93 MB
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Contemporary Treatments in Neurology

Author : Neil Scolding
File Size : 81.4 MB
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* A synopsis of current, novel and future therapeutic approaches to neurological disease * Recent treatment advances with evidence-based assessment of their impact * Chapters written by international experts within each particular area * Provides a synopsis of current, novel and future therapeutic approaches to neurological disease. * Discusses recent treatment advances with objective assessment of their impact * Chapters are written by international experts within each particular area

Nature Reviews

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File Size : 73.50 MB
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Neuromuscular Diseases

Author : Rahman Pourmand
File Size : 53.22 MB
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This authoritative clinical text provides you with practical approaches to the diagnosis and therapy of neuromuscular diseases. Written by leading neuromuscular specialists, this book offers you expert opinions on how to manage a wide range of neuromuscular disorders. * A thorough and practical clinical reference on the diagnosis and treatment of neuromuscular diseases * Each chapter written by leading neuromuscular specialists who provides you with expert advice and clinical pearls * You can apply the practical lessons learned to their management of patients in the clinic

Saunders Manual of Neurologic Practice

Author : Randolph W. Evans
File Size : 28.36 MB
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This new resource is custom-formatted to expedite clinical reference for the busy practitioner. It delivers comprehensive coverage of neurologic signs and symptoms, diagnostic approaches, and disorders. A unique, user-friendly format makes it remarkably easy for readers to look up whatever information they need. Facilitates the localization of unknown conditions with a signs and symptoms approach. Details how to obtain the best results from today's diagnostic modalities, including EEG, EMG, MRI, and more. Provides specific, step-by-step guidelines to expedite diagnosis and treatment for the neurologic and psychiatric disorders most commonly seen in practice. Deliver information quickly with a consistent organization in each chapter, a concise outline format, and at-a-glance boxes, tables, and illustrations throughout.

Cardiac Electrophysiology

Author : Douglas P. Zipes
File Size : 75.76 MB
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In response to the many major recent developments in the field, the authors have completely updated this modern classic, making this edition the most significant revision yet. Practitioners will find all the state-of-the-art guidance they need to make informed, effective clinical decisions.

Neuromuscular Function and Disease

Author :
File Size : 47.75 MB
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Muscle Diseases

Author : Anthony Henry Vernon Schapira
File Size : 33.64 MB
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This concise disorder-specific clinical text on muscle diseases covers current and new concepts in patient management. Due to advances in molecular genetics, the field of muscle diseases is evolving rapidly and clinicians need to stay abreast of the latest developments in diagnosis and treatment. Neuromuscular specialists and general neurologists will benefit from the cutting edge knowledge contained within this authoritative text. * Chapters written by a renowned set of international contributors * Provides a new approach to the dystrophies by classifying them according to the molecular basis of their abnormality * Includes 12 color photographs

Ion Channels and Disease

Author : Frances M. Ashcroft
File Size : 65.84 MB
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Calcium A Matter of Life or Death

Author :
File Size : 66.19 MB
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Calcium is a versatile carrier of signals regulating many aspects of cellular activity such as fertilization to create a new life and programmed cell death to end it. Calcium homeostasis is strictly controlled by channels, pumps and exchangers functioning as gates for calcium entry and release. Given that calcium is such a versatile messenger the field of calcium signaling is continuously and rapidly expanding. This book reviews the most recent developments in calcium signaling by leading experts in the field. It is a state-of-the-art summary of our present knowledge in this quickly growing field and provides insight into the impressive progress made in many areas of calcium signaling, while reminding us of how much remains to be learned.