Search results for: american-trypanosomiasis-chagas-disease-one-hundred-years-of-research

American Trypanosomiasis

Author : Jenny Telleria
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Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: The host: human and mammalian reservoirs The insect vectors: domestic and sylvatic vectors The causative parasite: Trypanosoma cruzi Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts

American Trypanosomiasis Chagas Disease

Author : Jenny Telleria
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American Trypanosomiasis, Chagas Disease: One Hundred Years of Research, Second Edition, provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease, the host, the insect vectors, and the causative parasite. In addition, new insights on the molecular biology and diagnostics of Chagas diseases, the persistence of infections in the host, and the interaction of the parasite and host metabolism are now included in this new and updated edition. Provides a thoroughly revised, updated, and streamlined new edition with contributions from leading authorities and industry experts Informs and updates on all the latest developments of Chagas disease, covering biology, clinical aspects, and human sciences Includes a summarizing chapter that provides key insights of practical significance for prevention efforts

Miller Fowler s Zoo and Wild Animal Medicine Current Therapy Volume 9 E Book

Author : Eric R. Miller
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Bringing together a globally diverse range of timely topics related to zoo and wild animals, Fowler’s Zoo and Wild Animal Medicine, Volume 9 is an invaluable tool for any professional working directly with wildlife and zoo animals. The text’s user-friendly format guides readers through biology, anatomy, and special physiology; reproduction; restraint and handling; housing requirements; nutrition and feeding; surgery and anesthesia; diagnostics, and therapeutics for each animal. Two new co-editors and a globally diverse group of expert contributors each lend their expertise on a wide range of new topics — including a new section on emerging wildlife diseases covering topics like MERS, Equine Herpesvirus, and Ebola in great apes. Other new topics integrated into this ninth volume include: stem cell therapy in zoo medicine, cardiac disease in great apes, disease risk assessment in field studies, Tasmanian devil tumors, and the latest information on the elephant herpes virus. With all its synthesized coverage of emerging trends, treatment protocols, and diagnostic updates new to the field, Fowler’s is a reference you don’t want to be without. Current therapy format ensures that each CT volume in the series covers all new topics that are relevant at the time of publication. Synthesized topics offer the right amount of depth — often fewer than 10 pages — to maintain an accessible format. General taxon-based format covers all terrestrial vertebrate taxa plus selected topics on aquatic and invertebrate taxa. Updated information from the Zoological Information Management System (ZIMS) has been incorporated to keep readers up to date on this worldwide system. Globally diverse panel of expert contributors each incorporate the latest research and clinical management of captive and free-ranging wild animals throughout the world. NEW! Two new co-editors (for a total of three editors) each lend their expertise on a wide range of new wild and zoo animal topics. NEW! Section on emerging wildlife diseases includes chapters on MERS, SARS, Ebola in great apes, and a variety of other emerging wildlife diseases.

Dog Parasites Endangering Human Health

Author : Christina Strube
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This book presents the latest information on canine parasites with zoonotic potential, to help avoid human infections. Compiled by international specialists, it covers protozoa, ectoparasites and helminth species of clinical importance in dogs, as well as the state of the art in diagnosis, preventive measures and potentially necessary treatment schemes. Dogs are commonly kept in families around the world and can predispose their human companions to disease. Updating and deepening insights from other specialist literature, the book is intended for practitioners and scientists alike. It also offers practical guidance for veterinary and human physicians and highlights unexplored research areas, making it a valuable resource for students and educated non-experts with an interest in parasitology, infectiology and zoonotic pet diseases.

Neonatal Infections

Author : Joseph B. Cantey
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There are approximately 4 million newborns annually in the United States, including 400,000 infants born preterm. This care occurs in nurseries of all acuity levels, sizes, and regions across the country and is provided by a variety of providers, including pediatricians, family practice doctors, nurse practitioners, and physician assistants. The most common complication during the newborn period is suspected or proven infection – either those acquired during the delivery itself or before delivery in the womb. Indeed, 4 of the 8 most commonly-prescribed medications in newborns annually are antibiotics. Therefore, these providers must all be knowledgeable about the clinical presentation, epidemiology, and approach to diagnosis, treatment and prevention of neonatal infections. However, many of these nurseries do not have convenient access to pediatric infectious disease consultation or support, and would benefit from a convenient reference guide. This book effectively and succinctly covers the pathophysiology, epidemiology, clinical presentation, approach to diagnosis and treatment, and important aspects of preventative care for the most frequently encountered neonatal and congenital infections. The first section discusses common neonatal infections (i.e., those acquired during or after delivery), including sepsis, meningitis, pneumonia, and other focal infections. The second section covers the most frequently encountered congenital infections (i.e., those acquired via the placenta while the fetus is still in-utero). Finally, the concluding section discusses the basics of infection prevention in the nursery setting, including general principles of infection prevention, how to apply those principles to families, and how to manage a suspected outbreak of infection within a nursery. This book is a unique contribution to the field. Existing texts such as the AAP Red Book fold neonatal infections in within chapters on a given pathogen, but the information is difficult to find and access quickly. By covering neonatal and congenital infections thoroughly while still keeping each section clear and concise, this Handbook will be a valuable resource for the busy nursery provider.

Biology of Foodborne Parasites

Author : Lihua Xiao
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While a number of introductory books on basic and molecular biology are available, none highlight the foodborne parasitic pathogens. Until now. A state-of-the-art review, Biology of Foodborne Parasites charts significant progress and outlines key biological techniques applied to foodborne parasitic pathogens research. The book covers basic biology, genetics and genomics, epidemiology, pathogenesis, diagnosis, control, and prevention. It showcases recent research that can then be used to spark further breakthroughs. The book addresses challenging issues in food pathogen detection. It details individual foodborne protists and helminthes, with each chapter following a similar format for a consistent presentation of information. It discusses topics ranging from basic biology, genetics and genomics, molecular detection and typing, and pathogenesis to epidemiology, molecular epidemiology, treatment and prevention, among other current concerns. It also details the methods used to diagnose the infection, characterize the pathogen, and detect parasites in three food commodities: meats, water, and fresh produce. With chapters written by experts in their respective fields, the book presents a reliable roadmap for future development of improved, innovative biological and molecular methods for analysis of foodborne parasitic pathogens. A handy, comprehensive reference on all aspects of biology of foodborne parasites, it highlights research needs and directions, helping you develop advanced diagnostic tools and new intervention measures.

The Heart in Rheumatic Autoimmune and Inflammatory Diseases

Author : Udi Nussinovitch
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The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

Neglected Tropical Diseases Latin America and the Caribbean

Author : Carlos Franco-Paredes
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This book addresses the major neglected tropical diseases (NTDs) – based on their prevalence and the years of healthy life lost to disability – in Latin American and Caribbean countries. These include Chagas disease, leishmaniasis, hookworm infection, and other soil-transmitted helminth infections, followed by dengue, schistosomiasis, leishmaniasis, leprosy, cysticercosis, bartonellosis, Plasmodium vivax malaria, and onchocerciasis. Topics like disease burden, major manifestations and approaches to the control and elimination of NTDs in Latin America and the Caribbean are discussed in detail. As such, the book will be of general interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of this region of the world.​

Human Emerging and Re emerging Infections

Author : Sunit Kumar Singh
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Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Human Emerging and Re emerging Infections 2 Volume Set

Author : Sunit Kumar Singh
File Size : 85.56 MB
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Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Ferri s Clinical Advisor 2018 E Book

Author : Fred F. Ferri
File Size : 20.25 MB
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Ferri’s Clinical Advisor 2018 is the most efficient, intuitive, and thorough resource of its kind, trusted by physicians to provide current diagnosis and treatment recommendations for hundreds of common medical conditions. The renowned "5 books in 1" format organizes vast amounts of data in a user-friendly, accessible manner, allowing quick retrieval of essential information. You’ll find guidance on diseases and disorders, differential diagnoses, and laboratory tests– updated annually by experts in key clinical fields. Medical algorithms and clinical practice guidelines round out the core content. Updated content by experts in key clinical fields helps you keep pace with the speed of modern medicine. Popular "5 books in 1" format includes cross-references, outlines, bullets, tables, boxes, and algorithms to help expedite search. Features 30 all-new topics, including Zika virus, hepatitis E, asthma-COPD overlap syndrome, drug-induced parenchymal lung disease, binge eating disorder, hereditary breast and ovarian cancer syndrome, transient global amnesia, and more. Updates 900 topics with the latest developments in medicine over the past year. Contains significantly expanded coverage throughout, including nearly 200 new illustrations, more than 100 new tables and boxes, 50 new differential diagnoses, and 30 new algorithms.

Ferri s Clinical Advisor 2017 E Book

Author : Fred F. Ferri
File Size : 78.10 MB
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Access up-to-date diagnostic and treatment information on more than 700 common medical conditions with Ferri’s Clinical Advisor 2017, which boasts the popular "5 books in 1" format! Published annually and now in its 19th year, it provides quick guidance on diseases and disorders, differential diagnoses, medical algorithms, laboratory tests, and clinical practice guidelines, while additional electronic content equips you with e-only topics, images, tables, and much more. Updated content by experts in key clinical fields helps you keep pace with the speed of modern medicine. Popular "5 books in 1" format includes cross-references, outlines, bullets, tables, boxes, and algorithms to help expedite search. Diseases and Disorders section features more than 300 new figures and tables, as well as 20 new topics including: cyclic vomiting syndrome, traveler’s diarrhea, chronic pruritus, post-herpetic neuralgia, enteropathic arthritis, and hoarding disorder. Differential Diagnosis section highlights 50 new topics, including: alcohol-related seizures, dysentery and inflammatory enterocolitis, hair loss, cystic and solid pancreatic lesions, and COPD decompensation. New algorithms offer important diagnostic information on 19 added conditions, including allergic reaction to vaccines, cardiac arrest, occupational asthma, urinary tract infection, and vertigo and dizziness. Current ICD-10 insurance billing codes help expedite insurance reimbursements.

Maxcy Rosenau Last Public Health and Preventive Medicine Sixteenth Edition

Author : Matthew L. Boulton
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Now in full color, the #1 text spanning the fields of public health and preventive medicine brings you fully up to date on the issues and topics you need to know Maxcy-Rosenau-Last Public Health and Preventive Medicine has been updated and revised for the first time in more than a decade. This highly anticipated and extensive edition provides the most current information and insights available on evidence-based public health and preventive medicine, from basic methodologies of public health to principles of epidemiology and infection control to environmental toxicology to global health. The most comprehensive resource of its kind, Maxcy-Rosenau-Last Public Health and Preventive Medicine is the clear choice for anyone seeking a career in public health. Features: • Edited and written by a who's who of global experts • 384 photos and illustrations • New full-color format and improved artwork • Significantly expanded coverage of diseases and preventive methods common in international markets • Greater use of tables and summary lists for easier reading and retention

Bulletin of the World Health Organization

Author : World Health Organization
File Size : 27.8 MB
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Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis

Author : TDR Disease Reference Group on Chagas Disease, Human African Trypanosomiasis and Leishmaniasis
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"This report provides a review and analysis of the research landscape for three diseases--Chagas disease, human African Trypanosomiasis and leishmaniasis--that dispropotionally afflict poor and remote populations with limited access to health services. It represents the work of the disease reference group on Chagas Disease, human African Trypanosomiasis, and leishmaniasis (DRG3) which was established to identify key research priorities through review of research evidence and input from stakeholders' consultations. The diseases, which are caused by related protozoan parasites, are described in terms of their epidemiology and disease burden, clinical forms and pathogenesis, HIV coinfection, diagnosis, drugs and drug resistance, vaccines, vector control, and health-care interventions. Priority areas for research are identified based on criteria such as public health relevance, benefit and impact on poor populations and equity, and feasibility. The priorities are found in the areas of diagnostics, drugs, vector control, asymptomatic infection, economic analysis of treatment and vector control methods, and in some specific issues such as surveillance methods or transmission-blocking vaccines for particular diseases. This report will be useful to researchers, policy and decision makers, funding bodies, implementation organizations, and civil society."--P. 4 of cover.

Archives of Medical Research

Author :
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New Approaches in American Trypanosomiasis Research

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Bulletin of the Pan American Health Organization

Author :
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Clinical and Vaccine Immunology

Author :
File Size : 66.27 MB
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Chagas Disease

Author : Fernanda Ramos Gadelha
File Size : 51.32 MB
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Chagas disease is a parasitosis caused by Trypanosoma cruzi, that affects approximately 10 million people around the world, mainly in Latin America. There are different types of transmission, and in the last few years, due to the increase in human migration, this pathology has been detected in other continents. Awareness that this disease is now found in places far from endemic areas is relevant since it leads to the development of strategies to prevent potential sources of transmission. The disease was discovered 100 years ago, and until now, no vaccine has been developed and the drugs currently in use, benznidazole and nifurtimox, have limited efficacy and potentially serious side effects. Chagas disease patients can have gastrointestinal, heart and nervous system related complications, requiring precise and rapid methods of diagnosis. The biology of T. cruzi has been intensively studied allowing for the translation of basic scientific knowledge into a number of selected drug candidates for the development of a more specific treatment. Coverage of the latest research techniques and advances in the topics mentioned above, and, most importantly, the new therapeutic targets noted for the development of an improved therapy will be discussed.