Staphylococcus

DOWNLOAD NOW »

Author: Greg A. Somerville

Publisher: Caister Academic Press

ISBN: 1910190500

Category: Medical

Page: 398

View: 8644

In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Staphylococcus

Molecular Genetics

DOWNLOAD NOW »

Author: Jodi A. Lindsay

Publisher: Horizon Scientific Press

ISBN: 1904455298

Category: Science

Page: 278

View: 527

Focusing on the staphylococcal genetics, this title brings together the expertise and enthusiasm of an international panel of leading staphylococcal researchers to provide a state-of-the-art overview of the field.

Staphylococci in Human Disease

DOWNLOAD NOW »

Author: Kent B. Crossley,Kimberly K. Jefferson,Gordon L. Archer,Vance G. Fowler

Publisher: John Wiley & Sons

ISBN: 9781444308471

Category: Medical

Page: 640

View: 842

Staphylococci remain the most important cause of hospital-acquiredinfections in the U.S. and MRSA has become the most common cause ofskin and soft tissue infection in many parts of the world. There is now a much greater understanding of the physiology andevolution of the staphylococci and this new edition reflects therapid advancements in knowledge about this pathogen and provides acomprehensive review from both clinical and basic scienceperspectives. The first section addresses the basic biology of thestaphylococci, their molecular genetics, host defenses and hostevasion, virulence determinants, mechanisms of antibioticresistance, and laboratory techniques. The second section dealswith epidemiology, and the third section provides an overview ofthe varied clinical manifestations of human staphylococcalinfections. The fourth section covers prevention and treatment ofthese often life-threatening infections. Written by experts from around the globe, this book is essentialreading for all clinicians and basic scientists studying thestaphylococci.

Next-generation Sequencing and Bioinformatics for Plant Science

DOWNLOAD NOW »

Author: Vijai Bhadauria

Publisher: Caister Academic Press

ISBN: 1910190667

Category: Science

Page: 202

View: 8909

Next-generation sequencing coupled with high-performance computing methods have revolutionised the field of plant breeding and genetics. In this timely overview of the field, expert scientists review current developments in next-generation sequencing and bioinformatics and discuss their application in understanding and improving agronomic traits such as yield, drought tolerance and disease resistance. The up-to-date reviews cover genome assembly and annotation, omics technologies, structural variations, abnormal chromosome number, chromosomal rearrangement, copy number variation, mobile elements, sequencing of small RNA nucleotides and transcription factor binding sites. Specific topics include the evolution analysis of rice, maize, sorghum and orchids, fruit development and ripening, plant disease resistance, fusarium head blight and stripe rust resistance in wheat and rice, host defence and pathogen virulence, crop design with improved resistance, and biotic and abiotic stress tolerance. This is a useful review of current developments in next-generation sequencing and essential reading for plant geneticists and crop scientists.

Brewing Microbiology

DOWNLOAD NOW »

Author: Nicholas A. Bokulich

Publisher: Caister Academic Press

ISBN: 1910190624

Category: Science

Page: 338

View: 8175

Research into brewing yeast and other organisms associated with beer and brewing has experienced many important advances in the past decade, propelled by technological advances in tools fundamental to the investigation of microbes and their metabolism. This volume surveys the most recent discoveries in brewing microbiology, with an emphasis on omics techniques and other modern technologies. Discoveries in these areas have furthered our knowledge of brewing processes, with practical applications from barley growth and malting to yeast management, strain selection, fermentation control, and quality assurance. The chapters, written by experts in the field, aim not only to illuminate recent progress, but also to discuss its impact on brewing practices. Topics covered include the physiology, fermentation, taxonomy, diversity, typing, genetic manipulation, genomics and evolution of brewing yeasts. Further areas covered include the fungal contamination of barley and malt, spoilage by lactic acid bacteria and gram-negative bacteria, and beer-spoiling yeasts. This volume is highly recommended for anyone involved in the microbiology of brewing.

Bacillus

DOWNLOAD NOW »

Author: Peter L. Graumann

Publisher: Caister Academic Press

ISBN: 1910190586

Category: Medical

Page: 478

View: 5783

The third edition of this authoritative reference work is indispensable to Bacillus scientists and invaluable for anyone involved in bacterial cell biology. Revised, updated and expanded with two new chapters on motility and nucleotide regulation, the new edition provides up-to-date reviews on current Bacillus research. Subjects covered include chromosome replication, DNA repair, chromosome segregation, cell division, transcription and translation, RNA-mediated regulation, general and regulatory proteolysis, the MreB cytoskeleton, membrane proteins, the cell wall, sporulation, biofilms, multicellularity and social behaviour, competence and transformation, motility and nucleotide regulation. An essential book for anyone involved in Bacillus and an invaluable reference work for those working in fields as diverse as medicine, biotechnology, agriculture, food and industry. A recommended acquisition for all microbiology laboratories.

Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms

DOWNLOAD NOW »

Author: Louise Bye,Neil Modi,Miles Stanford

Publisher: OUP Oxford

ISBN: 0199584990

Category: Medical

Page: 288

View: 740

An indispensable and fully comprehensive textbook, this covers the basic sciences in ophthalmology and is the only book you need to pass the FRCOphth Part 1 exam.

Physiology and Genetics

Selected Basic and Applied Aspects

DOWNLOAD NOW »

Author: Timm Anke,Daniela Weber

Publisher: Springer Science & Business Media

ISBN: 9783642002861

Category: Science

Page: 410

View: 3893

In the last decade the discipline of mycology has been substantially changed by new research technologies. In particular DNA-based tools for the investigation of fungal taxonomy, signal transduction and regulation, and biosynthetic potential have accelerated advances in mycological knowledge. This volume presents a selection of exciting issues on basic and applied aspects of fungal physiology and genetics. In 18 chapters renowned experts provide an overview of traditional as well as current and future aspects of potential application of fungi in biotechnology. The contributions can be used by scientists to keep up-to-date on the latest developments in the corresponding research area, and by students to familiarize themselves with the different topics.

Medizinische Mikrobiologie

DOWNLOAD NOW »

Author: Ernest Jawetz,Joseph L. Melnick,Edward A. Adelberg

Publisher: Springer-Verlag

ISBN: 3662001551

Category: Science

Page: N.A

View: 6176

Die Autoren haben beabsichtigt, diejenigen Gebiete der medizinischen Mikrobiologie kurz, exakt und in ihrem gegenwärtigen Stand darzustellen, die für die Infektionskrankheiten und ihre Chemotherapie von besonderer Bedeutung sind. Das Buch wendet sich in erster Linie an Medizinstudenten, außerdem an alle Ärzte in Krankenhaus und Praxis. Die Notwendigkeit für ein klares Verständnis der mlkrobiologischen Grundtatsachen ist in den letzten Jahren stärker geworden, da in Biochemie, Virologie und Chemotherapie so wie auf weiteren, die Medizin beeinflussenden Gebieten bedeutende Entwicklungen statt gefunden haben. Ein wesendicher Teil dieses Lehrbuches ist deswegen der Darstellung der Grundlagen gewidmet, wodurch sich das Buch auch für die Einführung des Studenten in den mikrobiologischen Kurs als brauchbar erweisen wird. Für die neue Auflage wurde ein Kapitel über Virus und Krebs neu geschrieben, und das Kapitel über antimikrobielle Chemotherapie wurde von Grund auf neu bearbeitet. Die Autoren freuen sich, bei dem Erscheinen der 7. amerikanischen Ausgabe von einer spanischen, deutschen, italienischen und griechischen Ausgabe, sowie von der Vorbereitung für eine serbokroatische Übersetzung berichten zu können. Die Autoren möchten nochmals allen danken, die ihnen bei der Bearbeitung dieser Auf lage behilflich waren, und die es ihnen durch ihre Kommentare und ihre Kritik ermöglicht haben, die in 2jährigen Abständen erscheinenden Revisionen dieses Buches auf dem neu esten Stand zu halten. ERNEsr JAWETZ JOSEPH L MELNICK San Frandsco, August 1966 EnWARD A AnELBERG III Inhaltsverzeichnis 1 Kapitell Die ~lt der Mikroben 8 Kapitel 2 Cytologie der Bakterien Optische Methoden 8 9 Eukaryote Zellstrukturen Prokaryote Zellstrukturen . 12 14 Cytoplasmatische Strukturen. 27 Färbeverfahren .

Human Physiology and Health

DOWNLOAD NOW »

Author: David B. Wright

Publisher: Heinemann

ISBN: 9780435633042

Category: General Certificate of Secondary Education

Page: 284

View: 5515

This human biology text covers the Human Physiology and Health GCSE syllabuses (NEAB and SEG) and is suitable for GNVQ Health and Social Care. It is written for post-16 students who may have struggled with science GCSEs, or are studying the subject with a particular vocational focus.

Eine kurze Geschichte der Menschheit

DOWNLOAD NOW »

Author: Yuval Noah Harari

Publisher: DVA

ISBN: 364110498X

Category: History

Page: 528

View: 7920

Krone der Schöpfung? Vor 100 000 Jahren war der Homo sapiens noch ein unbedeutendes Tier, das unauffällig in einem abgelegenen Winkel des afrikanischen Kontinents lebte. Unsere Vorfahren teilten sich den Planeten mit mindestens fünf weiteren menschlichen Spezies, und die Rolle, die sie im Ökosystem spielten, war nicht größer als die von Gorillas, Libellen oder Quallen. Vor 70 000 Jahren dann vollzog sich ein mysteriöser und rascher Wandel mit dem Homo sapiens, und es war vor allem die Beschaffenheit seines Gehirns, die ihn zum Herren des Planeten und zum Schrecken des Ökosystems werden ließ. Bis heute hat sich diese Vorherrschaft stetig zugespitzt: Der Mensch hat die Fähigkeit zu schöpferischem und zu zerstörerischem Handeln wie kein anderes Lebewesen. Anschaulich, unterhaltsam und stellenweise hochkomisch zeichnet Yuval Harari die Geschichte des Menschen nach und zeigt alle großen, aber auch alle ambivalenten Momente unserer Menschwerdung.

Nutraceutical and Functional Food Processing Technology

DOWNLOAD NOW »

Author: Joyce I. Boye

Publisher: John Wiley & Sons

ISBN: 1118504976

Category: Technology & Engineering

Page: 400

View: 2122

For several years, the food industry has been interested inidentifying components in foods which have health benefits to beused in the development of functional food and nutraceuticalproducts. Examples of these ingredients include fibre,phytosterols, peptides, proteins, isoflavones, saponins, phyticacid, probiotics, prebiotics and functional enzymes. Although muchprogress has been made in the identification, extraction andcharacterisation of these ingredients, there remains a need forready and near-market platform technologies for processing theseingredients into marketable value-added functional food andnutraceutical products. This book looks at how these ingredientscan be effectively incorporated into food systems for market, andprovides practical guidelines on how challenges in specific foodsectors (such as health claims and marketing) can be addressedduring processing. Nutraceutical and Functional Food Processing Technologyis a comprehensive overview of current and emerging trends in theformulation and manufacture of nutraceutical and functional foodproducts. It highlights the distinctions between foods falling intothe nutraceutical and functional food categories. Topics includesustainable and environmentally–friendly approaches to theproduction of health foods, guidelines and regulations, and methodsfor assessing safety and quality of nutraceutical and functionalfood products. Specific applications of nutraceuticals in emulsionand salad dressing food products, beverages and soft drinks, bakedgoods, cereals and extruded products, fermented food products arecovered, as are novel food proteins and peptides, and methods forencapsulated nutraceutical ingredients and packaging. The impact ofprocessing on the bioactivity of nutraceutical ingredients,allergen management and the processing of allergen-free foods,health claims and nutraceutical food product commercialization arealso discussed. Nutraceutical and Functional Food Processing Technologyis a comprehensive source of practical approaches that can be usedto innovate in the nutraceutical and health food sectors. Fullyup-to-date and relevant across various food sectors, the book willbenefit both academia and industry personnel working in the healthfood and food processing sectors.

Staphylococcus aureus Infection and Disease

DOWNLOAD NOW »

Author: Allen Honeyman,Herman Friedman,Mauro Bendinelli

Publisher: Springer Science & Business Media

ISBN: 0306468484

Category: Medical

Page: 330

View: 9813

Staphylococcus aureus is now acknowledged as being the most important bacterial pathogen of humans. It usually produces localized disease but can be rapidly invasive, spreading through the tissues, invading bone, and seeding the bloodstream to produce a fulminant picture of septic shock, disseminated intravascular coagulation, and rapid death. Moreover, most strains of staph infections are becoming resistant to most antibiotics, thus posing a significant problem for hospitals and health care facilities. This book, a volume in the Infectious Agents and Pathogenesis series, presents chapters by the major researchers in the field.

Handbook of Fermented Meat and Poultry

DOWNLOAD NOW »

Author: Fidel Toldrá

Publisher: John Wiley & Sons

ISBN: 1118522672

Category: Technology & Engineering

Page: 528

View: 1855

Fermented meat products have been consumed for centuries in many different parts of the world and constitute one of the most important groups of food. Bacterial cultures are used in their manufacture to preserve the meat and confer particular textures and sensory attributes. Examples of fermented meats include salami, chorizo, pepperoni and saucisson. This fully revised and expanded reference book on meat fermentation presents all the principle fermented meat products and the processing technologies currently used in their manufacture. The 54 chapters of this substantial book are grouped into the following sections: Meat fermentation worldwide: overview, production and principles Raw materials Microbiology and starter cultures for meat fermentation Sensory attributes Product categories: general considerations Semidry-fermented sausages Dry-fermented sausages Other fermented meats and poultry Ripened meat products Biological and chemical safety of fermented meat products Processing sanitation and quality assurance There are five new chapters in the second edition that address the following topics: Smoking and new smoke flavourings; Probiotics; Methodologies for the study of the microbial ecology in fermented sausages; Low sodium in meat products; and Asian sausages. Handbook of Fermented Meat and Poultry, Second Edition provides readers with a full overview of meat fermentation, the role of microorganisms naturally present and/or added as starter cultures, safety aspects and an account of the main chemical, biochemical, physical and microbiological changes that occur in processing and how they affect final quality. Finally, readers will find the main types of worldwide fermented meat products, typically produced in different areas, with the description of their main characteristics.

Anatomy and Physiology for Midwives E-Book

DOWNLOAD NOW »

Author: Jane Coad,Melvyn Dunstall

Publisher: Elsevier Health Sciences

ISBN: 0702045934

Category: Medical

Page: 472

View: 5851

Anatomy & Physiology for Midwives 3rd edition builds on the success of the first two editions with electronic ancillaries, more accessible, woman-centred language and strengthened links with good practice. The book provides a thorough review of anatomy and physiology applicable to midwifery, from first principles through to current research, utilizing case studies for reflection. A comprehensive and well-illustrated textbook that is an essential purchase for all students of midwifery.

The Staphylococci and staphylococcal pathogenesis

DOWNLOAD NOW »

Author: David Heinrichs,Martin J. McGavin

Publisher: Frontiers E-books

ISBN: 2889190579

Category:

Page: N.A

View: 5559

Members of the genus Staphylococcus play important roles in disease causation in humans and animals. Over the past decade, the completed sequencing of many staphylococcal genomes has contributed to a surge in the number of publications, which have promoted a tremendous advance in our knowledge of these important pathogens. Significant developments include the emergence of new and highly virulent strains of S. aureus, advances in tracking the evolution of human and animal adapted strains, a heightened appreciation of the role of mobile genetic elements in antibiotic resistance and pathogenesis, and important insights into staphylococcal physiology, immune evasion strategies, and cell surface proteins, as well as significant advances in vaccine development and therapeutics. This Research Topic will focus attention on the latest developments in these areas as they pertain to S. aureus and members of the coagulase-negative Staphylococci, and will also strive to identify areas of future development.

Bacterial Toxins

Genetics, Cellular Biology and Practical Applications

DOWNLOAD NOW »

Author: Thomas Proft

Publisher: Horizon Scientific Press

ISBN: 1908230282

Category: Bacterial toxins

Page: 234

View: 9311

Toxins are virulence determinants that play an important role in microbial pathogenicity and/or evasion of the host immune response. This makes them ideal targets for the development of novel antimicrobial strategies. The potential applications of toxin research extend beyond simply combating microbial pathogens, and include use as novel anti-cancer drugs and other front-line medicines and as tools in neurobiology. In the field of cellular biology, toxins have become invaluable as tools for the manipulation and investigation of fundamental cellular and physiological processes. Research in this area is thriving and is at a very exciting stage. This timely volume serves as an update on the most important recent advances in the genetics, cellular biology, and practical applications of the most important bacterial toxins. Written by internationally respected scientists, the topics reviewed include: the molecular basis and risk factors for verotoxin pathogenesis * molecular mechanisms of Helicobacter pylori CagA translocation and function * structure and mechanisms of action of pore-forming toxins * bacterial enterotoxins as immunomodulators and vaccine adjuvants * mobile genetic elements as carriers for bacterial virulence genes * the novel family of staphylococcal superantigen-like toxins (SSLs) * new insights into the use of botulinum neurotoxins as therapeutics * microbial toxins as tools in cell biology * the role of the large clostridial cytotoxins in C. difficile disease.

Molecular and Quantitative Animal Genetics

DOWNLOAD NOW »

Author: Hasan Khatib

Publisher: John Wiley & Sons

ISBN: 1118677374

Category: Science

Page: 336

View: 5286

Animal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits. Molecular and Quantitative Animal Genetics is a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. Molecular and Quantitative Animal Genetics will be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals. Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.

Gentechnologie für Einsteiger

DOWNLOAD NOW »

Author: Terence A. Brown

Publisher: Springer

ISBN: 9783827413024

Category:

Page: 409

View: 2140

T. A. Browns "Gentechnologie fA1/4r Einsteiger" hat sich in mehreren Auflagen international als StandardeinfA1/4hrung in die Genklonierung und DNA-Analyse etabliert. Das Grundlagenlehrbuch setzt nur wenig Kenntnisse in Molekularbiologie und Genetik voraus und erlAutert in klarer Sprache sowohl die fundamentalen Prinzipien der wichtigsten gentechnologischen Methoden als auch die immer breiter werdende Palette ihrer Anwendungen. Die groAe Bedeutung der Gentechnologie fA1/4r die Grundlagenforschung und fA1/4r neue Entwicklungen in Biotechnologie und Medizin wird klar herausgearbeitet. Aoeber 250 zweifarbige Illustrationen erleichtern das VerstAndnis des Stoffes und machen die Konzepte und Arbeitstechniken der Gentechnologen anschaulich. Die neue Auflage ist vollstAndig A1/4berarbeitet und enthAlt zwei neue Kapitel. Eines prAsentiert die Methoden, mit denen man ganze Genome sequenziert, und beschreibt, was man aus den gewonnenen Sequenzinformationen ablesen kann. Das zweite widmet sich den Anwendungen der Gentechnologie in der Gerichtsmedizin - ein spannendes und aufschlussreiches Beispiel des Einsatzpotenzials der DNA-Analyse. Der groAen Bedeutung der Polymerasekettenreaktion (PCR) entsprechend wird diese Technik jetzt in einem frA1/4hen Abschnitt des Buches behandelt und durchgehend stArker berA1/4cksichtigt.