Recent Advances in BIS Guided TCI Anesthesia

DOWNLOAD NOW »

Author: David A. Ferreira,Luis Antunes,Pedro Amorim,Catarina Nunes

Publisher: Nova Science Pub Incorporated

ISBN: 9781616686277

Category: Medical

Page: 66

View: 6115

Anaesthetic drugs with a rapid onset of action and a short half-live, such as the hypnotic propofol and the analgesic opioid remifentanil, allow easy control of the anaesthetic depth and noxious stimuli associated to surgical interventions, and reveal most of the potential of target controlled infusion for general anaesthesia. Furthermore, mathematical models were incorporated in microcomputers in delivery system devices, calculating the drug concentrations in the blood and brain, according to the infusion rate. This book approaches the characteristics of propofol and remifentanil that allow the fast emergence of target controlled infusion for general anaesthesia, and its potential for closed loop control anaesthesia.

Core Topics in Paediatric Anaesthesia

DOWNLOAD NOW »

Author: Ian James,Isabeau Walker

Publisher: Cambridge University Press

ISBN: 1107244188

Category: Medical

Page: N.A

View: 1222

This book covers all of the important elements of paediatric anaesthesia in a concise and structured manner. From the premature infant to the teenager, readers are guided through the complexities they may encounter, with key points at the end of each chapter to summarise the most important information. The common surgical conditions encountered in daily practice are covered along with comprehensive discussion of consent and the law, safeguarding children, and the complexity of drug dosing in the paediatric population. Other topics covered include trauma, burns, resuscitation, principles of intensive care, and transporting a sick child. Each chapter is written by an acknowledged expert in their field, sharing a wealth of relevant, practical experience. Covering the whole curriculum necessary for advanced training, this is essential reading for trainees, general anaesthetists managing children in non-specialist hospitals and anyone aspiring to become a paediatric anaesthetist, as well as those established in the field.

Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care

DOWNLOAD NOW »

Author: Alan David Kaye,Adam M. Kaye,Richard D. Urman

Publisher: Springer

ISBN: 1461489482

Category: Medical

Page: 904

View: 1745

In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) “black box” warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians.

The Wondrous Story of Anesthesia

DOWNLOAD NOW »

Author: Edmond I Eger II,Lawrence J. Saidman,Rod N. Westhorpe

Publisher: Springer Science & Business Media

ISBN: 1461484413

Category: Medical

Page: 944

View: 2201

Edited and written by an international "who's who" of more than 100 authors, including anesthesiologists, nurse anesthetists, bench scientists, a surgeon, and representatives of industry, this text provides a comprehensive history of anesthesia, unique in its focus on the people and events that shaped the specialty around the world, particularly during the past 70 years when anesthesia emerged from empiricism and developed into a science-based practice.

Total Intravenous Anesthesia and Target Controlled Infusions

A Comprehensive Global Anthology

DOWNLOAD NOW »

Author: Anthony R. Absalom,Keira P. Mason

Publisher: Springer

ISBN: 3319476092

Category: Medical

Page: 824

View: 4572

This is a comprehensive and authoritative presentation of total intravenous anesthesia (TIVA) and target controlled infusion (TCI). The editors’ international reputation has enabled them to recruit leading experts from around the world to write single-author chapters in their area of expertise. Total Intravenous Anesthesia and Target Controlled Infusions is the first multi-disciplinary, globally authored volume on the topic. Providing a single source of information on all aspects of TIVA and TCI, from pharmacologic modeling and the pharmacology of intravenous anesthetic drugs to practical considerations in the clinical setting and the requirements of special populations, Total Intravenous Anesthesia and Target Controlled Infusions examines the debate about the risks and advantages of TIVA, analyze outcome studies, and provides guidance on creating a curriculum to teach TIVA and TCI.

Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care

Key Topics and Practical Approaches

DOWNLOAD NOW »

Author: Antonio M. Esquinas

Publisher: Springer

ISBN: 3319042599

Category: Medical

Page: 466

View: 6178

This book establishes the indications for the use of NIV in the context of weaning from invasive mechanical ventilation. It provides a comprehensive overview of key topics relevant for correct practical application, including NIV and weaning principles, important aspects of patient care before and after weaning, and pediatric and neonatology weaning. Finally, the book summarizes international guidelines and new perspectives of NIV during weaning. With contributions by international experts in the field on noninvasive mechanical ventilation, the book will serve as a valuable guide for critical care physicians, respiratory physiotherapists, and pulmonologists.

Core Topics in Neuroanaesthesia and Neurointensive Care

DOWNLOAD NOW »

Author: Basil F. Matta,David K. Menon,Martin Smith

Publisher: Cambridge University Press

ISBN: 1139499858

Category: Medical

Page: N.A

View: 7339

Core Topics in Neuroanesthesia and Neurointensive Care is an authoritative and practical clinical text that offers clear diagnostic and management guidance for a wide range of neuroanesthesia and neurocritical care problems. With coverage of every aspect of the discipline by outstanding world experts, this should be the first book to which practitioners turn for easily accessible and definitive advice. Initial sections cover relevant anatomy, physiology and pharmacology, intraoperative and critical care monitoring and neuroimaging. These are followed by detailed sections covering all aspects of neuroanesthesia and neurointensive care in both adult and pediatric patients. The final chapter discusses ethical and legal issues. Each chapter delivers a state-of-the art review of clinical practice, including outcome data when available. Enhanced throughout with numerous clinical photographs and line drawings, this practical and accessible text is key reading for trainee and consultant anesthetists and critical care specialists.

Perioperative Care of the Elderly

Clinical and Organizational Aspects

DOWNLOAD NOW »

Author: Gabriella Bettelli

Publisher: Cambridge University Press

ISBN: 1108166784

Category: Medical

Page: N.A

View: 4893

This innovative, comprehensive book covers the key elements of perioperative management of older patients. The book's chapter structure coincides with the clinical path patients tread during their treatment, from preoperative evaluation to post-hospital care. Epidemiological aspects and aging processes are illustrated, providing keys to understanding the quick expansion of geriatric surgery and defining the clinical profile of older surgical patients in a cybernetic perspective. Preoperative evaluation and preparation for surgery, including medication reconciliation and pre-habilitation, are developed in the light of supporting decision-making about surgery in an evidence-based and patient-focused way. Intra- and postoperative management are discussed, aiming to tailor anesthetic, surgical and nursing approaches to specific patients' needs, in order to prevent both general and age-related complications. This volume also addresses issues relevant to geriatric surgery, from different organizational models to clinical risk management and systems engineering applied to hospital organization.

Handbook of Ambulatory Anesthesia

DOWNLOAD NOW »

Author: Rebecca S. Twersky,Beverly K. Philip

Publisher: Springer Science & Business Media

ISBN: 9780387733296

Category: Medical

Page: 484

View: 3447

This second edition of the Handbook of Ambulatory Anesthesia has been completely updated and expanded to reflect current practice guidelines and trends in ambulatory anesthesia. This practical manual covers preoperative evaluation, patient and procedure selection, anesthetic techniques, postoperative management, and quality assurance. Additionally, the editors have included all new information on anesthesia for minimally invasive surgery as well as office-based procedures. Written and edited by experts who have developed successful practices at the world's leading institutions, Handbook of Ambulatory Anesthesia includes a broad representation of perspectives and approaches for practitioners in every ambulatory setting.

The Structured Oral Examination in Anaesthesia

Practice Papers for Teachers and Trainees

DOWNLOAD NOW »

Author: Shyam Balasubramanian,Cyprian Mendonca,Colin Pinnock

Publisher: Cambridge University Press

ISBN: 0521680506

Category: Medical

Page: 276

View: 1980

Comprising questions and answers which simulate examination format, this is an essential aid for anaesthesia trainees

Nanoparticulate Drug Delivery Systems

DOWNLOAD NOW »

Author: Deepak Thassu,Michel Deleers,Yashwant Vishnupant Pathak

Publisher: CRC Press

ISBN: 9781420008449

Category: Medical

Page: 376

View: 8645

With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS— including lipid nanoparticles for dermal applications; nanocarriers for the treatment of restenosis; and for ocular, central nervous system, and gastrointestinal applications. It also explores its use as an adjuvant for vaccine development. Supplying insight from international experts, this guide Discusses formulation for poorly soluble drugs Presents biological requirements for nanotherapeutic applications Demonstrates the role of nanobiotechnology in the development of nanomedicine Documents recent advances in nanoparticulate technology—including electrospining, formation of microcrystals, and production of liquid crystalline phases Examines the technology of metallic nanoparticles

Anesthesia for Renal Transplantation

DOWNLOAD NOW »

Author: Gwendolyn B. Graybar,Lois L. Bready

Publisher: Springer Science & Business Media

ISBN: 1461320356

Category: Medical

Page: 272

View: 3661

This treatise commemorates the 32nd anniversary of the first successful allogenic kidney transplant in a human being and the beginning of a con tinuing challenge for well over a generation of anesthesiologists. If compari sons can be permitted, this epoch-making event can be ranked with the first pulmonary lobectomy and subsequently the initial ligation of a patent ductus arteriosus in the late 1930s when thoracic and cardiac surgery began. Was it merely a coincidence that brought these events to the fore so close upon one another after many years of ideation and frustration? Not so, according to Lewis Thomas, for this was the time of medicine's second revolution-its transformation from an empirical art into a powerfully effective science. The remote Galenic conception of disease with its emphasis on disturbed body humors was about to be supplanted by effective therapeutics, as signified by the introduction of the sulfonamides and antibiotics for the specific treatment of infection. Anesthesiology had been dormant up to that era, still relying upon a few agents, more or less utilized from the beginning, and purveyed by a handful of specialists who had not yet begun to ask the scientific questions necessary for their maturation into a bona fide discipline. However, anesthesiology was in evitably caught in the ferment, for as Peter Caws observed, "It serves to re mind us that the development of science is a step-wise process: nobody starts from scratch and nobody gets very far ahead of the rest.

Primary Care English

DOWNLOAD NOW »

Author: Ramón Ribes,Isabel Garcia Gimeno,Roger Jones

Publisher: Springer Science & Business Media

ISBN: 3540496173

Category: Medical

Page: 506

View: 7877

This book is the ideal introduction to the medical English language used in primary care and in hospitals. It is written for family doctors and other health care professionals involved in primary care around the world who want to advance their medical English. The language of the consultation is central to this book and its contents modulated according to real clinical practice. The reader is expected to have at least an intermediate level of English.

Neuroanesthesia and Cerebrospinal Protection

DOWNLOAD NOW »

Author: Hiroyuki Uchino,Kazuo Ushijima,Yukio Ikeda

Publisher: Springer

ISBN: 4431544909

Category: Medical

Page: 725

View: 2400

This book is a knowledge-based text that covers the anatomy, neurophysiology, and neuropharmacology needed to carry out the necessary management and cerebrospinal protection during neuroanesthesia. Especially to make the subject of neuroanesthesia more approachable, we introduce surgical measures utilized in neurosurgery, cardiovascular surgery, neuromodulation, and related procedures. The main purpose of neuroanesthesia/neurocritical care is to deliver cerebrospinal protection in neurosurgical and cardiovascular surgeries. How should we select the best anesthetic management to prevent neurological complications for patients who, for instance, undergo different types of surgery for subarachnoid hemorrhage, stroke, head trauma, carotid endarterectomy, or cardiovascular surgery under cardiopulmonary bypass? These pathological conditions include the risk of transient cerebrospinal ischemia, and if our management is not precise, it may induce serious neurological sequelae. Although there is an urgent need to establish the treatment and elucidate the molecular mechanisms of cerebrospinal injury, many components are intertwined, making this a challenge we have not completely solved yet. This volume makes the management of neuroanesthesia more accessible not only for primary residents but also for specialists, providing a valuable resource on the current perspectives of neuroanesthesia.

Applied Pharmacometrics

DOWNLOAD NOW »

Author: Stephan Schmidt,Hartmut Derendorf

Publisher: Springer

ISBN: 1493913042

Category: Medical

Page: 565

View: 8569

This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and pharmacodynamic concepts of pharmacometrics in drug development, the book presents numerous examples of specific applications that utilize pharmacometrics with modeling and simulations over a variety of therapeutic areas, including pediatrics, diabetes, obesity, infections, psychiatrics, Alzheimer’s disease, and dermatology, among others. The examples illustrate how results from all phases of drug development can be integrated in a more timely and cost-effective process. Applying pharmacometric decision tools during drug development can allow objective, data-based decision making. At the same time, the process can identify redundant or unnecessary experiments as well as some costly clinical trials that can be avoided. In addition to cost saving by expedited development of successful drug candidates, pharmacometrics has an important economic impact in drug product selection. Unsuccessful drug candidates can be identified early and discontinued without expending efforts required for additional studies and allocating limited resources. Hence, pharmacometric modeling and simulation has become a powerful tool to bring new and better medications to the patient at a faster pace and with greater probability of success.

Bioequivalence Studies in Drug Development

Methods and Applications

DOWNLOAD NOW »

Author: Dieter Hauschke,Volker Steinijans,Iris Pigeot

Publisher: Wiley

ISBN: 9780470094754

Category: Medical

Page: 328

View: 8880

Studies in bioequivalence are the commonly accepted method to demonstrate therapeutic equivalence between two medicinal products. Savings in time and cost are substantial when using bioequivalence as an established surrogate marker of therapeutic equivalence. For this reason the design, performance and evaluation of bioequivalence studies have received major attention from academia, the pharmaceutical industry and health authorities. Bioequivalence Studies in Drug Development focuses on the planning, conducting, analysing and reporting of bioequivalence studies, covering all aspects required by regulatory authorities. This text presents the required statistical methods, and with an outstanding practical emphasis, demonstrates their applications through numerous examples using real data from drug development. Includes all the necessary pharmacokinetic background information. Presents parametric and nonparametric statistical techniques. Describes adequate methods for power and sample size determination. Includes appropriate presentation of results from bioequivalence studies. Provides a practical overview of the design and analysis of bioequivalence studies. Presents the recent developments in methodology, including population and individual bioequivalence. Reviews the regulatory guidelines for such studies, and the existing global discrepancies. Discusses the designs and analyses of drug-drug and food-drug interaction studies. Bioequivalence Studies in Drug Development is written in an accessible style that makes it ideal for pharmaceutical scientists, clinical pharmacologists, and medical practitioners, as well as biometricians working in the pharmaceutical industry. It will also be of great value for professionals from regulatory bodies assessing bioequivalence studies.

Awareness During Anesthesia

DOWNLOAD NOW »

Author: Mohamed M. Ghoneim

Publisher: Butterworth-Heinemann Medical

ISBN: N.A

Category: Medical

Page: 181

View: 8291

* First comprehensive source on facts about consciousness while under anesthesia * Includes a detailed pharmacology of drugs * Details techniques for detection and prevention. * Author is leading expert in field

Anesthetic Pharmacology 2 Part Set

Basic Principles and Clinical Practice

DOWNLOAD NOW »

Author: Alex S. Evers,Mervyn Maze,Evan D. Kharasch

Publisher: Cambridge University Press

ISBN: 9780521896665

Category: Medical

Page: 1210

View: 6893

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, second edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

The I-Gel Supraglottic Airway

DOWNLOAD NOW »

Author: Pavel Michalek,William Donaldson

Publisher: Nova Science Pub Incorporated

ISBN: 9781624178979

Category: Medical

Page: 231

View: 672

The I-Gel supraglottic airway is a diposable, latex-free device for airway management during anaesthesia. The design of this device is significantly different from the previously used devices, notably laryngeal mask airways. Its bowl is made of a soft, non-inflatable thermoplastic elastomer, anatomically preformed to mirror the perilaryngeal structure. The I-Gel contains an additional epiglottis rest, which helps to prevent the epiglottis from down-folding or obstructing the laryngeal inlet. The device also includes a gastric channel, allowing drainage of air and gastric contents or passage of a gastric tube. This book provides a brief history of airway management and the classification of supraglottic airway devices; the mechanisms and forces contributing to their seal, and highlights the main differences between the devices. Also discussed is the process of I-Gel development including an initial mannequin and cadaver studies, with a description of the I-Gel's use in clinical practice, indications and description of its use in the operating room, and use of the I-Gel in different surgical subspecialities including laparoscopic procedures.