Reactive Intermediates

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Author: Christopher J. Moody,Gordon Harlow Whitham

Publisher: Oxford University Press on Demand

ISBN: 9780198556725

Category: Science

Page: 89

View: 1338

Neutral reactive intermediates -- radicals, carbenes, nitrenes, and aryenes -- occupy a fascinating place in the history of organic chemistry. First regarded as mere curiosities, neutral reactive intermediates ultimately came under the intense scrutiny of physical organic chemists from a mechanistic point-of-view. This concise text concentrates on how these electron-deficient species now play a key role in synthetic chemistry research. Important reactions are clearly and simply laid out with carefully chosen examples that illustrate their use in organic synthesis. Each chapter includes problems as well as suggestions for further reading. Undergraduates will find Reactive Intermediates an invaluable summary of this important topic in organic chemistry--one that fills a gap created by the superficial treatment accorded these valuable compounds in most chemistry textbooks.

Aromatic Chemistry

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Author: Malcolm Sainsbury

Publisher: Oxford University Press on Demand

ISBN: 0198556748

Category: Science

Page: 92

View: 9652

All the basic principles of the field of aromatic chemistry are clearly presented in this important account. Many compounds of industrial and biological significance are used as examples with consideration given to structure, reactions, and properties. Topics such as thermodynamic versus kinetic control and pericyclic reactions are also introduced. In addition to benzene and the classes of aromatic compounds derived from it, the text covers polycyclic arenes, and the small and large ring systems which are embraced by the wider definition of aromaticity. The text will be especially useful for courses in organic chemistry.

Mechanisms of Organic Reactions

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Author: Howard Maskill

Publisher: Oxford University Press

ISBN: 9780198558224

Category: Science

Page: 96

View: 8983

Focusing on organic reactions, this text begins by introducing modern technology, definitions, and concepts of mechanisms and reactivity. The following four chapters are accounts of the mechanisms of four of the main classes of reactions of aliphatic compounds.

Polar rearrangements

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Author: Laurence M. Harwood

Publisher: Oxford University Press, USA

ISBN: 9780198556718

Category: Language Arts & Disciplines

Page: 96

View: 3008

The general principles of polar rearrangements are brought together in this undergraduate chemistry text, which deals with all the major rearrangements involving electron-deficient atoms or charged intermediates. Reactions involving migration to electron-deficient carbon, nitrogen, oxygen and sulphur, and sigmatropic rearrangements involving polar species, are thus treated in a coherent and consistent manner. Clear discussions of the reaction mechanisms are followed by examples of synthetic applications providing a concise yet comprehensive account of the nature and importance of these processes.

Structure and Reactivity in Organic Chemistry

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Author: Howard Maskill

Publisher: OUP Oxford

ISBN: 9780198558200

Category: Science

Page: 100

View: 533

This book covers areas of mechanistic and physical organic chemistry at advanced undergraduate level in a non-mathematical way. The topics included (e.g. kinetics and mechanism, catalysis, and isotope effects) are essential in any modern chemistry degree, yet are not included in standard organic chemistry text books for undergraduates. The book is thoroughly up to date and includes many examples from all areas of organic chemistry.

Stereoselectivity in Organic Synthesis

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Author: Garry Procter

Publisher: OUP Oxford

ISBN: 9780198559573

Category: Science

Page: 98

View: 301

This clear and concise text is concerned with the reactions used in stereoselective organic synthesis. These are important types of reactions which can be used for the selective preparation of new organic compounds with a defined and predictable three dimensional architecture. This informative text will be an invaluable study aid for all undergraduate chemistry students. Undergraduates in related subjects studying chemistry to second year level or higher will also find this book useful.

Organic Synthesis

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Author: Christine L. Willis

Publisher: Oxford University Press, USA

ISBN: 9780198557913

Category: Science

Page: 91

View: 1403

Organic chemists need to know how to design effective syntheses. This Primer uses a wide range of examples to teach students how to adopt a logical and flexible approach to the design of synthetic routes. It describes how then to design and control syntheses, and compares four syntheses of pyrrolidine alkaloids using the principles elucidated in the main text. Practice examples are provided throughout, making this concise book a useful study resource for the undergraduate.

Pericyclic Reactions

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Author: Ian Fleming

Publisher: Oxford University Press, USA

ISBN: 0199680906

Category: Addition reactions

Page: 118

View: 9732

Key texts in the renowned Oxford Chemistry Primers series have been fully refreshed and updated to suit the needs of today's students, lecturers, and postgraduate researchers. The rigorous and yet accessible treatment of each subject area is ideal for those wanting to know more about a particular topic not covered comprehensively in existing undergraduate texts. Moreover, cutting-edge examples and applications throughout the texts show the relevance of thechemistry being described to the real world. Pericyclic reactions constitute a fundamental class of organic chemistry, including such commercially important synthetic reactions as theDiels-Alder reaction. This primer gives a concise and accessible account of these reactions, enabling students to recognise the different types of pericyclic reaction and understand their application in organic synthesis.

Molecular Orbitals and Organic Chemical Reactions

Reference Edition

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Author: Ian Fleming

Publisher: John Wiley & Sons

ISBN: 1119964679

Category: Science

Page: 526

View: 2088

Winner of the PROSE Award for Chemistry & Physics 2010 Acknowledging the very best in professional and scholarly publishing, the annual PROSE Awards recognise publishers' and authors' commitment to pioneering works of research and for contributing to the conception, production, and design of landmark works in their fields. Judged by peer publishers, librarians, and medical professionals, Wiley are pleased to congratulate Professor Ian Fleming, winner of the PROSE Award in Chemistry and Physics for Molecular Orbitals and Organic Chemical Reactions. Molecular orbital theory is used by chemists to describe the arrangement of electrons in chemical structures. It is also a theory capable of giving some insight into the forces involved in the making and breaking of chemical bonds—the chemical reactions that are often the focus of an organic chemist's interest. Organic chemists with a serious interest in understanding and explaining their work usually express their ideas in molecular orbital terms, so much so that it is now an essential component of every organic chemist's skills to have some acquaintance with molecular orbital theory. Molecular Orbitals and Organic Chemical Reactions is both a simplified account of molecular orbital theory and a review of its applications in organic chemistry; it provides a basic introduction to the subject and a wealth of illustrative examples. In this book molecular orbital theory is presented in a much simplified, and entirely non-mathematical language, accessible to every organic chemist, whether student or research worker, whether mathematically competent or not. Topics covered include: Molecular Orbital Theory Molecular Orbitals and the Structures of Organic Molecules Chemical Reactions — How Far and How Fast Ionic Reactions — Reactivity Ionic Reactions — Stereochemistry Pericyclic Reactions Radical Reactions Photochemical Reactions This expanded Reference Edition of Molecular Orbitals and Organic Chemical Reactions takes the content and the same non-mathematical approach of the Student Edition, and adds extensive extra subject coverage, detail and over 1500 references. The additional material adds a deeper understanding of the models used, and includes a broader range of applications and case studies. Providing a complete in-depth reference for a more advanced audience, this edition will find a place on the bookshelves of researchers and advanced students of organic, physical organic and computational chemistry. The student edition of Molecular Orbitals and Organic Chemical Reactions presents molecular orbital theory in a simplified form, and offers an invaluable first textbook on this important subject for students of organic, physical organic and computational chemistry. Further information can be viewed here. "These books are the result of years of work, which began as an attempt to write a second edition of my 1976 book Frontier Orbitals and Organic Chemical Reactions. I wanted to give a rather more thorough introduction to molecular orbitals, while maintaining my focus on the organic chemist who did not want a mathematical account, but still wanted to understand organic chemistry at a physical level. I'm delighted to win this prize, and hope a new generation of chemists will benefit from these books." -Professor Ian Fleming

Reactive Intermediates in Organic Chemistry

Structure, Mechanism, and Reactions

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Author: Maya Shankar Singh

Publisher: John Wiley & Sons

ISBN: 3527678271

Category: Science

Page: 296

View: 648

Most reactions in organic chemistry do not proceed in a single step but rather take several steps to yield the desired product. In the course of these multi-step reaction sequences, short-lived intermediates can be generated that quickly convert into other intermediates, reactants, products or side products. As these intermediates are highly reactive, they cannot usually be isolated, but their existence and structure can be proved by theoretical and experimental methods. Using the information obtained, researchers can better understand the underlying reaction mechanism of a certain organic transformation and thus develop novel strategies for efficient organic synthesis. The chapters are clearly structured and are arranged according to the type of intermediate, providing information on the formation, characterization, stereochemistry, stability, and reactivity of the intermediates. Additionally, representative examples and a problem section with different levels of difficulty are included for self-testing the newly acquired knowledge. By providing a deeper understanding of the underlying concepts, this is a musthave reference for PhD and Master Students in organic chemistry, as well as a valuable source of information for chemists in academia and industry working in the field. It is also ideal as primary or supplementary reading for courses on organic chemistry, physical organic chemistry or analytical chemistry.

Photochemistry of Organic Compounds

From Concepts to Practice

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Author: Petr Klán,Jakob Wirz

Publisher: John Wiley & Sons

ISBN: 1405190884

Category: Science

Page: 563

View: 4609

This new volume in the Postgraduate Chemistry Series provides a thorough overview of the principles and uses of synthetic organic photochemistry. Appropriate at postgraduate and research level it will also serve as a reference for more experienced workers.

Applied Organometallic Chemistry and Catalysis

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Author: Robin Whyman

Publisher: OUP Oxford

ISBN: 9780198559177

Category: Science

Page: 97

View: 7723

This Primer has two main objectives: to provide an overview of the influence of organometallic chemistry on homogeneous and heterogenous catalysis and to provide an account of the principle commercial applications of homogeneous catalysis in industry. The book builds on the coverage of organometallic chemistry in two Primers by Bochmann, OCPs 12 and 13.

Advanced Organic Chemistry

Reactions and Mechanisms

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Author: Bernard Miller

Publisher: Prentice Hall

ISBN: 9780130655882

Category: Science

Page: 411

View: 8800

This text discusses important organic reactions and mechanisms not usually covered in depth in Introductory Organic Chemistry courses. Rather than reviewing topics discussed in introductory courses or attempting to cover all aspects of Organic Chemistry, Miller methodically guides readers through more advanced topics to pique and retain interest and make essential principles and practices accessible to all. Topics covered include Heterocyclic Chemistry, reactions of organic molecules and their mechanisms, Organophosphorus and Organosulfur Chemistry, and more. Ideal for all chemists and other professionals who already have a background in Organic Chemistry, Physical Organic Chemistry, Stereochemistry, or Spectroscopy, etc., and who need additional knowledge about organic reactions.

Functional Groups

Characteristics and Interconversions

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Author: G. Denis Meakins

Publisher: Oxford University Press, USA

ISBN: N.A

Category: Science

Page: 92

View: 1263

The characteristic properties of functional groups and the methods for interconverting them are the foundations of organic chemistru central to all first year University organic chemistry courses. This primer will provide an extremely useful introduction to reactions of functional groups in a concise and systematic form.

Fundamentals of Asymmetric Catalysis

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Author: Patrick J. Walsh,Marisa C. Kozlowski

Publisher: University Science Books

ISBN: 9781891389542

Category: Science

Page: 674

View: 9056

The field of asymmetric catalysis plays an increasingly large role in chemical synthesis as the demand for single-enantiomer starting materials, intermediates, and products rises. This book describes the essential aspects of enantioselective catalysis in a clear, logical fashion, with chapters organized by concept rather than by reaction type. Each concept is supported by carefully selected examples to give the reader broad exposure to a wide range of catalysts, reactions, and reaction mechanisms.

The Art of Writing Reasonable Organic Reaction Mechanisms

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Author: Robert B. Grossman

Publisher: Springer Science & Business Media

ISBN: 0387954686

Category: Science

Page: 360

View: 2736

Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.

Organic Stereochemistry

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Author: Michael J. T. Robinson

Publisher: Oxford University Press on Demand

ISBN: 9780198792758

Category: Science

Page: 89

View: 4607

This book is an account for students of how the three-dimensional shapes of molecules influence their chemical and physical properties. It begins with the structures of molecules and then describes how such structures can be changed.

Chemistry of Peptide Synthesis

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Author: N. Leo Benoiton

Publisher: CRC Press

ISBN: 1420027697

Category: Science

Page: 304

View: 2889

Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions. Incorporating elements from the author’s role of Career Investigator of the Medical Research Council of Canada and his extensive teaching career, the book emphasizes learning rather than memorization. The text uses clear language and schematics to present concepts progressively, carefully excluding unnecessary details and providing a historical context in which to appreciate the development of the field. The author first outlines the fundamentals of peptide synthesis, focusing on the intermediates in aminolysis reactions. Gradually the text builds into discussions of the applicability of coupling reactions, stereomutation, methods of deprotection, solid-phase synthesis, side-chain protection and side reactions, and amplification on coupling methods. The book clarifies the differences between oxazolones from amino-acid derivatives and segments and the implications of their formation on the chiral integrity of products. The author offers a critical analysis of the mechanisms of coupling reactions and the desirability of preactivation. The text explains hindrance and the nucleophilicity of tertiary amines and rationalizes their use. The book also explores mechanisms of acidolysis and the dual role of nucleophiles as reactants and scavengers. Chemistry of Peptide Synthesis supplies a broad, yet straightforward approach that appeals to those with limited knowledge of organic chemistry or chemists from other fields as well as in-depth coverage that can be appreciated by experienced peptidologists.

Strategic Applications of Named Reactions in Organic Synthesis

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Author: Laszlo Kurti,Barbara Czako

Publisher: Elsevier

ISBN: 0080575412

Category: Science

Page: 864

View: 1274

Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings