Molecules and Medicine

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Author: E. J. Corey,Barbara Czakó,László Kürti

Publisher: John Wiley & Sons

ISBN: 1118361733

Category: Science

Page: 272

View: 5391

Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

Bioactive Molecules and Medicinal Plants

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Author: Kishan Gopal Ramawat,Jean-Michel Mérillon

Publisher: Springer Science & Business Media

ISBN: 354074603X

Category: Science

Page: 379

View: 7040

This book on medicinal plant biotechnology covers recent developments in this field. It includes a comprehensive up-to-date survey on established medicinal plants and on molecules which gained importance in recent years. No recently published book has covered these carefully selected topics. The contributing scientists have been selected on the basis of their involvement in the related plant material as evident by their internationally recognised published work.

Health and Medicine

Challenges for the Chemical Sciences in the 21st Century

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Author: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Challenges for the Chemical Sciences in the 21st Century,Organizing Committee for the Workshop on Health and Medicine

Publisher: National Academies Press

ISBN: 0309087201

Category: Medical

Page: 76

View: 5964

The report assesses the current state of chemistry and chemical engineering within the context of drug discovery, disease diagnosis, and disease prevention. Also addressed are chemical and chemical engineering challenges in pharmaceutical synthesis, delivery, and manufacture.

Molecularizing Biology and Medicine

New Practices and Alliances, 1920s to 1970s

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Author: Soraya de Chadarevian,Harmke Kamminga

Publisher: Taylor & Francis

ISBN: 1135298017

Category: History

Page: 292

View: 5564

The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.

Applications of Electrochemistry and Nanotechnology in Biology and Medicine II

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Author: Noam Eliaz

Publisher: Springer Science & Business Media

ISBN: 1461421373

Category: Science

Page: 338

View: 6318

The study of electrochemical nanotechnology has emerged as researchers apply electrochemistry to nanoscience and nanotechnology. These two related volumes in the Modern Aspects of Electrochemistry Series review recent developments and breakthroughs in the specific application of electrochemistry and nanotechnology to biology and medicine. Internationally renowned experts contribute chapters that address both fundamental and practical aspects of several key emerging technologies in biomedicine, such as the processing of new biomaterials, biofunctionalization of surfaces, characterization of biomaterials, discovery of novel phenomena and biological processes occurring at the molecular level.

Khonjel March 2013

Free Citizens' Journal

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Author: N.A

Publisher: KHONJEL

ISBN: N.A

Category:

Page: N.A

View: 3188

www.khonjel.org Trial Publication

The HLA Complex in Biology and Medicine

A Resource Book

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Author: Narinder K Mehra

Publisher: Boydell & Brewer Ltd

ISBN: 9788184488708

Category: Medical

Page: 608

View: 1565

A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.

Vascular Adhesion Molecules and Inflammation

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Author: Jeremy D. Pearson

Publisher: Birkhäuser

ISBN: 3034887434

Category: Medical

Page: 260

View: 7893

The book will provide an overview of the roles of vascular adhesion molecules in health and disease, with chapters on their cell biology, followed by chapters reviewing their importance in specific disease processes. Vascular adhesion molecules are vital for the physiological processes of leukocyte trafficking and also critically involved in the enhanced leukocyte emigration that is a key feature of all inflammatory and immune diseases. The book is designed to provide up-to-date, linked reviews of the subject suitable for postgraduate students entering the field or research workers from allied disciplines needing a modern overview.

Heart Failure: New Insights for the Healthcare Professional: 2011 Edition

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Author: N.A

Publisher: ScholarlyEditions

ISBN: 1464900663

Category: Medical

Page: 269

View: 415

Heart Failure: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Heart Failure. The editors have built Heart Failure: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heart Failure in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Heart Failure: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Functional Studies Using NMR

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Author: V. Ralph McCready,Martin Leach,Peter J. Ell

Publisher: Springer Science & Business Media

ISBN: 1447114108

Category: Medical

Page: 206

View: 9831

This volume is based on a series of lectures delivered at a one-day teach ing symposium on functional and metabolic aspects of NMR measure ments held at the Middlesex Hospital Medical School on 1st September 1985 as a part of the European Nuclear Medicine Society Congress. Currently the major emphasis in medical NMR in vivo is on its poten tial to image and display abnormalities in conventional radiological im ages, providing increased contrast between normal and abnormal tissue, improved definition of vasculature, and possibly an increased potential for differential diagnosis. Although these areas are undeniably of major importance, it is probable that NMR will continue to complement con ventional measurement methods. The major potential benefits to be de rived from in vivo NMR measurements are likely to arise from its use as an instrument for functional and metabolic studies in both clinical re search and in the everyday management of patients. It is to this area that this volume is directed.

FLIM Microscopy in Biology and Medicine

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Author: Ammasi Periasamy,Robert M. Clegg

Publisher: CRC Press

ISBN: 9781420078916

Category: Science

Page: 472

View: 2474

Detecting Signals at the Single Molecule Level: Pioneering Achievements in Microscopy Recent advances have led to such remarkable improvements in fluorescence lifetime imaging microscopy’s (FLIM) capacity for contrast and sensitivity that researchers can now employ it to detect signals at the single molecule level. FLIM also offers the additional benefit of independence from fluorophore concentration and excitation intensity. Moreover, its unique sensitivity makes it an excellent reporter of conformational changes and of variations in the molecular surroundings of biological molecules. Most of this improvement and discovery have occurred during the past decade, and, to date, information that would benefit a broad range of researchers remains scattered in the literature. Edited by two of the top pioneers in the field, FLIM Microscopy in Biology and Medicine presents the fundamentals of FLIM along with a number of advanced considerations so that a wider audience can appreciate recent and potential improvements that make it such a valuable tool. New Opportunities for Biomedical Researchers... New Challenges for Microscopy Researchers Discussion sections in all the chapters clearly show the challenges for implementing FLIM for various applications. Certain chapters discuss limits on the number of photons required for highly accurate lifetime determinations, as well as the accuracy with which multiple, closely associated lifetime components can reliably be determined. Such considerations are important for the user when he or she is selecting the most advantageous method of FLIM to use for a particular application. While this book provides an introduction for those new to FLIM, it gathers a wealth of material to enhance the work of experts involved in pioneering technological improvements, as well as those research opportunities in this unique and promising area of microscopy.

Churchill Livingstone's Dictionary of Sport and Exercise Science and Medicine E-Book

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Author: Sheila Jennett

Publisher: Elsevier Health Sciences

ISBN: 0080982522

Category: Medical

Page: 496

View: 7023

The dictionary is designed to be a pocket companion, for ready access by students, postgraduates, trainers, and health professionals involved in sport and exercise. It provides definitions and short accounts of terms used and techniques employed in the study and practical application of the relevant anatomy, physiology, biomechanics and psychology, and of commonly associated medical problems and treatments. Illustrations are included in the A-Z text, and appendices provide additional reference information and sources for further study. Wide coverage in A-Z text of relevant basic and applied topics relevant to sport and exercise. Full contact information for professional associations. Illustrations, graphs and tables. Team of expert contributors.

Physics of NMR Spectroscopy in Biology and Medicine

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Author: B. Maraviglia

Publisher: Elsevier

ISBN: 0444597794

Category: Science

Page: 483

View: 1958

As a result of the recent expansion of nuclear magnetic resonance in biomedicine, a number of workshops and schools have been organized to introduce the NMR principles to a wider group of biologists, radiologists, neurologists, etc. The aim of most of these courses was to provide a common vocabulary and enough information about ``pulse sequences'', relaxation times, etc. in order to facilitate the use of the various types of NMR imaging systems. However, no courses were organized for the physicists who were responsible for the origin and evolution of the ideas in this area. This Enrico Fermi school was therefore organized. The topics discussed included the theoretical interpretation and prediction of NMR signals, the study of new imaging techniques up to the building of special r.f. coils and the study of new methods for analysing NMR data in the time domain.

Controlling the Quantum World of Atoms, Molecules, and Photons

An Interim Report

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Author: Board on Physics and Astronomy,Division on Engineering and Physical Sciences

Publisher: National Academies Press

ISBN: 030965565X

Category: Science

Page: 12

View: 3205

Atomic, molecular, and optical (AMO) science illustrates powerfully the ties of fundamental physics to society. Its very name comes from three of the twentieth century's greatest advances: the establishment of the atom as the building block of matter; the development of quantum mechanics, which made it possible to understand the inner workings of atoms and molecules; and the invention of the laser. Advances made possible by the scientists in this field touch almost every sphere of societal importance in the past century. Navigation by the stars gave way to navigation by clocks, which in turn has given way to today's navigation by atomic clocks. Laser surgery has replaced the knife for the most delicate operations. Homeland security relies on a multitude of screening technologies based on AMO research to detect toxins in the air and hidden weapons in luggage or on persons, to name a few. New drugs are now designed with the aid of x-ray scattering to determine their structure at the molecular level using AMO-based precision measurement techniques. And the global economy depends critically on high-speed telecommunication by laser light sent over thin optical fibers encircling the globe. AMO scientists are proud of their central role in science and society in the twentieth century, and they have been rewarded with numerous Nobel prizes over the past decade, including the 2005 prize in physics. But in this report we look to the future. The National Research Council of the National Academies has undertaken a study of opportunities in atomic, molecular, and optical (AMO) science and technology over roughly the next decade. The committee carrying out the AMO 2010 study, has been asked to assess the state of AMO science, emphasizing recent accomplishments and identifying new and compelling scientific questions. The six grand challenges, summarized below, will each form a chapter of the committee's final report: What is the nature of physical law? What happens at the lowest temperatures in the universe? What happens when we turn up the power? Can we control the inner workings of a molecule? How will we control and exploit the nanoworld? What lies beyond Moore's law? Controlling the Quantum World of Atoms, Molecules, and Photons: An Interim Report provides a preview of the final document. It summarizes the committee's opinion on the key opportunities in forefront AMO science and in closely related critical technologies and discusses some of the broad-scale conclusions of the final report. It also identifies how AMO science supports national R&D priorities.

Physiology and Medicine

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Author: Ivan Y. Torshin

Publisher: Nova Publishers

ISBN: 9781600217524

Category: Medical

Page: 302

View: 5249

Several years have passed since the sequencing of the human genome and what might be called "the post-genomic era" has begun. Of course, there are many different genomes and the term "post-genomic" does not necessarily imply the human genome. However, it is the data encoded in the human genome that hold the promise to be of practical importance in a wide range of biomedical applications. The sequencing and preliminary annotations of the human genome provided an incredible amount of the raw, largely unprocessed information. Coupled with the millions of publications on human physiology already available in public databases, it is clear that certain informational strategies should be adopted for the retrieval, analysis and representation of these data. Among biological sciences, bioinformatics is a specific branch that deals with managing complexities in the biological information. However, the bioinformatics is in no way restricted to the compilation of large databases or elaboration of sophisticated software. The methods of bioinformatics can greatly assist the generation of productive hypotheses that allow subsequent experimental testing followed by confirmation or disapproval. The main idea behind the present volume is not worrying about the steadily growing amounts of biomedical information or about the relative quality of it. This volume, as well as the entire book series, is based on the purpose-oriented attitude: how to make a good use of this information in particular research projects.

Ethics, Medical Research, and Medicine

Commercialism versus Environmentalism and Social Justice

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Author: Andrew Thompson,Iqbal S. Shergill,N. Temple

Publisher: Springer Science & Business Media

ISBN: 9401007942

Category: Philosophy

Page: 195

View: 9532

Andrew Thompson, Norman J. Temple We humans are an extraordinary species. One of our finest achievements is the development of morality, of a sense of right and wrong. We articulate and then impose this sensitivity upon ourselves in the form of ethical guidelines, rules, regulations, and laws. We have, regrettably, also developed marvelously clever ways of justifying our behavior whenever it runs afoul of these prescriptions. We have, for example, developed the concept of objectivity to guide scientific pursuits and subsequently established rights which undermine the possibility of ever coming close to attaining the goal of being objective -- rights which entitle participating scientists to gain personal, tangible profits from scientific discoveries. Formerly, we envisaged gods who kept us in place, who reminded us that we were not all-powerful or especially wise. Now we tend to worship our achievements, especially our technological ones, and ourselves. Mary Midgley' aptly names this phenomenon, "humanolatry." We have lost our respect for nature in our enthusiasm for changing it to that which suits our shortsighted ends. We must, as she says, "unlearn" this way of thinking.

Leukocyte Recruitment, Endothelial Cell Adhesion Molecules, and Transcriptional Control

Insights for Drug Discovery

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Author: Tucker Collins

Publisher: Springer Science & Business Media

ISBN: 9780792372233

Category: Medical

Page: 327

View: 8247

The localized attachment of circulating leukocytes to endothelium has been recognized as the cellular hallmark of the inflammatory response. This adhesive interaction, a necessary antecedent to the emigration of leukocytes from the blood into the tissues, is mediated by vascular adhesion molecules. Leukocyte Recruitment, Endothelial Cell Adhesion Molecules and Transcriptional Control: Insights for Drug Discovery outlines some of the cellular and molecular mechanisms of inflammation with contributions from top researchers. This volume provides an overview of three of these endothelial adhesion molecules, as examples of key mediators of leukocyte recruitment. It reviews the structure and regulation of these cell surface proteins and focus on the rapidly expanding field of transcriptional regulation of these inducible proteins, and closes with a discussion of drug discovery possibilities that target the regulation of leukocyte recruitment. This book will be of interest for any researchers, in academia or industry, looking for an overview of leukocyte recruitment or novel approaches to drug discovery.

Atoms, Molecules, and Light

AMO Science Enabling the Future

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Author: National Research Council,Division on Engineering and Physical Sciences,Board on Physics and Astronomy,Committee for an Updated Assessment of Atomic, Molecular, and Optical Science

Publisher: National Academies Press

ISBN: 0309086132

Category: Science

Page: 52

View: 8085

With the publication in 1994 of Atomic, Molecular, and Optical Science: An Investment in the Future (the FAMOS report), the National Research Council launched the series Physics in a New Era, its latest survey of physics. Each of the six area volumes in the survey focuses on a different subfield of physics, describing advances since the last decadal survey and suggesting future opportunities and directions. This survey culminated in 2001 with the publication of the seventh and final volume, Physics in a New Era: An Overview. Since the publication of the FAMOS report, the developments in atomic, molecular, and optical (AMO) science have been amazing. Significant advances in areas such as cooling and trapping, atom and quantum optics, single-atom and single-molecule detection, and ultrafast and ultra intense phenomena, along with the emergence of new applications, made it clear that an update of the FAMOS report was needed. With support from the National Science Foundation and the Department of Energy, the Committee for an Updated Assessment of Atomic, Molecular, and Optical Science was formed. The committee's statement of task reads as follows: The committee will prepare a narrative document that portrays the advances in AMO science and its impact on society. This report highlights selected forefront areas of AMO science, emphasizing recent accomplishments and new opportunities, identifies connections between AMO science and other scientific fields, emerging technologies, and national needs, describes career opportunities for AMO scientists. To accomplish its task and at the same time reach a broad audience, the committee decided to present its report in the form of a brochure highlighting selected advances, connections, and impacts on national needs. An exhaustive assessment of the field, which will fall within the purview of the next decadal survey, was not the goal of the update. The committee would like to express its gratitude for the informative interactions it had with many scientists and policy makers. Many colleagues completed a questionnaire and suggested topics to be included in this report. The final selection of topics was made in accordance with the criteria set forth in the statement of task. While this report was still being written, the tragic events of September 11, 2001, occurred. AMO science and its applications have already played and will continue to play a central role in our nation's response to terrorist threats from conventional as well as chemical or biological weapons. Some of the technology discussed in this report in the chapter "AMO Science Enhancing National Defense" was used successfully for the U.S. military response in Afghanistan-the Global Positioning System (GPS) and laser-guided munitions are just two examples. AMO science will also enable the development of early detection techniques that will help to neutralize the threat from biological and chemical agents.

Plasma Medicine

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Author: Alexander Fridman,Gary Friedman

Publisher: John Wiley & Sons

ISBN: 1118437659

Category: Science

Page: 592

View: 900

This comprehensive text is suitable for researchers and graduatestudents of a ‘hot’ new topic in medical physics. Written by the world’s leading experts, this bookaims to present recent developments in plasma medicine, bothtechnological and scientific, reviewed in a fashion accessible tothe highly interdisciplinary audience consisting of doctors,physicists, biologists, chemists and other scientists, universitystudents and professors, engineers and medical practitioners. The book focuses on major topics and covers the physics requiredto develop novel plasma discharges relevant for medicalapplications, the medicine to apply the technology not onlyin-vitro but also in-vivo testing and the biology to understandcomplicated bio-chemical processes involved in plasma interactionwith living tissues.