Determination of organic reaction mechanisms

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Author: Barry Keith Carpenter

Publisher: Wiley-Interscience

ISBN: N.A

Category: Science

Page: 247

View: 8446

This practical handbook presents concise descriptions of the most commonly employed experimental techniques for studying reaction mechanisms in organic chemistry. For each technique, all necessary theoretical background is covered, and at least one example of its application--taken from the research literature--is described in detail.

Organic Mechanisms

Reactions, Methodology, and Biological Applications

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Author: Xiaoping Sun

Publisher: John Wiley & Sons

ISBN: 1118507916

Category: Science

Page: 432

View: 1655

Instills a deeper understanding of how and why organic reactions happen Integrating reaction mechanisms, synthetic methodology, and biological applications, Organic Mechanisms gives organic chemists the tools needed to perform seamless organic reactions. By explaining the underlying mechanisms of organic reactions, author Xiaoping Sun makes it possible for readers to gain a deeper understanding of not only chemical phenomena, but also the ability to develop new synthetic methods. Moreover, by emphasizing biological applications, this book enables readers to master both advanced organic chemistry theory and practice. Organic Mechanisms consists of ten chapters, beginning with a review of fundamental physicochemical principles that are essential for understanding the nature of organic mechanisms. Each one of the remaining chapters is devoted to a major class of organic reactions, including: Aliphatic C–H bond functionalization Functionalization of the alkene C=C bond by cycloaddition reactions Nucleophilic substitutions on sp3-hybridized carbons Nucleophilic additions and substitutions on carbonyl groups Reactivity of the α-hydrogen to carbonyl groups Rearrangements A brief review of basic organic chemistry begins each chapter, helping readers move from fundamental concepts to an advanced understanding of reaction mechanisms. Key mechanisms are illustrated by expertly drawn figures highlighting microscopic details. End-of-chapter problems enable readers to put their newfound knowledge into practice by solving key problems in organic reactions with the use of mechanistic studies, and a Solutions Manual is available online for course instructors. Thoroughly referenced and current with recent findings in organic reaction mechanisms, Organic Mechanisms is recommended for upper-level undergraduates and graduate students in advanced organic chemistry, as well as for practicing chemists who want to further explore the mechanistic aspects of organic reactions.

Advanced Organic Chemistry

Reaction Mechanisms

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Author: Reinhard Bruckner

Publisher: Academic Press

ISBN: 9780121381103

Category: Science

Page: 636

View: 1098

Contents - Radical Substitution Reactions at the Saturated C Atom. Nucleophilic Substitution Reactions at the Saturated C Atom. Additions to the Olefinic C=C Double Bond. Eliminations Substitution Reactions on Aromatic Compounds. Nucleophilic Substitution Reactions (Except Through Enolates) on the Carboxyl Carbon. Additions of Heteroatom Nucleophiles to Heterocumulenes. Additions of Heteroatom Nucleophiles to Carbonyl Compounds and Their Secondary Reactions. Addition of H Nucleophiles and Metal Organyls to Carbonyl Compounds. Reaction of Ylides with Saturated or Unsaturated Carbonyl Compounds. Chemistry of the Alkaline Earth Metal Enolates. Rearrangements. Thermal Cycloadditions. Transition Metal-Mediated Alkenylations, Arylations and Alkynylations. Oxidations and Reductions.

A Handbook of Organic Chemistry Mechanisms

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Author: Peter Wepplo

Publisher: Curved Arrow Press

ISBN: 0977931331

Category: Science

Page: 160

View: 8669

A Handbook to Organic Chemistry Mechanisms is designed to accompany a standard organic chemistry textbook. The book presents complete mechanisms, start to finish, without any steps skipped or left out. The mechanisms have been carefully written to show each step in a logical and easy to follow format. Students have enthusiastically attested to the ease with which they could understand the mechanisms. Reaction mechanisms are one of the most challenging aspects of organic chemistry. This book is derived from Part D of A Guide to Organic Chemistry Mechanisms. That book is a guided inquiry workbook that shows students how to study and enables them to learn reaction mechanisms. Student knowledge is increased step by step by completing mechanisms at easy, moderate, and textbook levels of difficulty. A Handbook to Organic Chemistry Mechanisms also relies on example-based teaching. Chemical reactions can be learned in context, the way infants learn. Learning reactions from rules is difficult when there are many exceptions. Substitution and elimination reactions are noteworthy due to the number of conditions that must be accounted for. With example-based teaching, you can deduce the importance that stereochemistry, structure, solvent, leaving group, charge, basicity, or nucleophilicity may have on a reaction. A Handbook to Organic Chemistry Mechanisms has been designed with the principle that our brains are pattern-matching machines. Therefore, an emphasis has been placed upon the patterns of reactions. Each chapter represents a basic mechanistic theme. That theme is repeated with the examples. Insightful explanations have been included with the mechanisms. This book will be a valuable resourcefor reviewing for an exam, solving problems, or studying for the MCAT.

The Art of Writing Reasonable Organic Reaction Mechanisms

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Author: Robert B. Grossman

Publisher: Springer Science & Business Media

ISBN: 0387954686

Category: Science

Page: 360

View: 2890

Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.

Mechanisms of Organic Reactions

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Author: Howard Maskill

Publisher: Oxford University Press

ISBN: 9780198558224

Category: Science

Page: 96

View: 321

Focusing on organic reactions, this text begins by introducing modern technology, definitions, and concepts of mechanisms and reactivity. The following four chapters are accounts of the mechanisms of four of the main classes of reactions of aliphatic compounds.

Writing Reaction Mechanisms in Organic Chemistry

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Author: Audrey Miller,Philippa H. Solomon

Publisher: Academic Press

ISBN: 9780124967120

Category: Science

Page: 471

View: 9173

Writing Reaction Mechanisms in Organic Chemistry, Second Edition, is an invaluable guide to charting the movements of atoms and electrons in the reactions of organic molecules. Miller and Solomon illustrate that understanding organic reactions is based on applying general principles rather than the rote memorization of unrelated processes, and, in turn, emphasize that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. Students and research chemists alike will find this book useful in providing a method of organizing and synthesizing an oftentimes overwhelming quantity of information into a set of general principles and guidelines for determining and describing organic reaction mechanisms. * Essential for those students who need to have mechanisms explained in greater detail than most organic chemistry textbooks provide. * Illustrated with hundreds of chemical structures * Extensively rewritten and reorganized to make the presentation and format even easier for students to use * Contains many problem sets and answers to all problems to help students work through general principles and applications * Appendixes have been added to this edition that contain easily referenced information on Lewis structures, symbols for chemical notation, and the relative acidities of common substances

Writing Reaction Mechanisms in Organic Chemistry

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Author: Kenneth A. Savin

Publisher: Academic Press

ISBN: 0124105092

Category: Science

Page: 510

View: 7036

Writing Reaction Mechanisms in Organic Chemistry, Third Edition, is a guide to understanding the movements of atoms and electrons in the reactions of organic molecules. Expanding on the successful book by Miller and Solomon, this new edition further enhances your understanding of reaction mechanisms in organic chemistry and shows that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. The book has been extensively revised with new material including a completely new chapter on oxidation and reduction reactions including stereochemical reactions. It is also now illustrated with hundreds of colorful chemical structures to help you understand reaction processes more easily. The book also features new and extended problem sets and answers to help you understand the general principles and how to apply these to real applications. In addition, there are new information boxes throughout the text to provide useful background to reactions and the people behind the discovery of a reaction. This new edition will be of interest to students and research chemists who want to learn how to organize what may seem an overwhelming quantity of information into a set of simple general principles and guidelines for determining and describing organic reaction mechanisms. Extensively rewritten and reorganized with a completely new chapter on oxidation and reduction reactions including stereochemical reactions Essential for those who need to have mechanisms explained in greater detail than most organic chemistry textbooks provide Now illustrated with hundreds of colorful chemical structures to help you understand reaction processes more easily New and extended problem sets and answers to help you understand the general principles and how to apply this to real applications New information boxes throughout the text to provide useful background to reactions and the people behind the discovery of a reaction

Perspectives on Structure and Mechanism in Organic Chemistry, Solutions Manual

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Author: F. A. Carroll

Publisher: John Wiley & Sons

ISBN: 0470261153

Category: Science

Page: 173

View: 5034

Understanding organic structures and mechanisms form the basis of physical organic chemistry, and are necessary to grasping organic chemical reactions. A must-have resource for comprehending organic chemistry basics, Perspectives on Structure and Mechanism in Organic Chemistry clearly explains the basic physical organic chemistry necessary to understand the synthetic applications. This second edition is updated throughout with modern concepts, revised references, and additional study questions to improve and guide student understanding. This second edition remains a definitive and easy to understand text for students and professionals in organic chemistry.

Organic Mechanisms

Reactions, Stereochemistry and Synthesis

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Author: Reinhard Bruckner

Publisher: Springer Science & Business Media

ISBN: 3642036503

Category: Science

Page: 855

View: 9104

This English edition of a best-selling and award-winning German textbook Reaction Mechanisms: Organic Reactions · Stereochemistry · Modern Synthetic Methods is aimed at those who desire to learn organic chemistry through an approach that is facile to understand and easily committed to memory. Michael Harmata, Norman Rabjohn Distinguished Professor of Organic Chemistry (University of Missouri) surveyed the accuracy of the translation, made certain contributions, and above all adapted its rationalizations to those prevalent in the organic chemistry community in the English-speaking world. Throughout the book fundamental and advanced reaction mechanisms are presented with meticulous precision. The systematic use of red "electron-pushing arrows" allows students to follow each transformation elementary step by elementary step. Mechanisms are not only presented in the traditional contexts of rate laws and substituent effects but, whenever possible, are illustrated using practical, useful and state-of-the-art reactions. The abundance of stereoselective reactions included in the treatise makes the reader familiar with key concepts of stereochemistry. The fundamental topics of the book address the needs of upper-level undergraduate students, while its advanced sections are intended for graduate-level audiences. Accordingly, this book is an essential learning tool for students and a unique addition to the reference desk of practicing organic chemists, who as life-long learners desire to keep abreast of both fundamental and applied aspects of our science. In addition, it will well serve ambitious students in chemistry-related fields such as biochemistry, medicinal chemistry and pharmaceutical chemistry. From the reviews: "Professor Bruckner has further refined his already masterful synthetic organic chemistry classic; the additions are seamless and the text retains the magnificent clarity, rigour and precision which were the hallmark of previous editions. The strength of the book stems from Professor Bruckner’s ability to provide lucid explanations based on a deep understanding of physical organic chemistry and to limit discussion to very carefully selected reaction classes illuminated by exquisitely pertinent examples, often from the recent literature. The panoply of organic synthesis is analysed and dissected according to fundamental structural, orbital, kinetic and thermodynamic principles with an effortless coherence that yields great insight and never over-simplifies. The perfect source text for advanced Undergraduate and Masters/PhD students who want to understand, in depth, the art of synthesis ." Alan C. Spivey, Imperial College London "Bruckner’s ‘Organic Mechanisms’ accurately reflects the way practicing organic chemists think and speak about organic reactions. The figures are beautifully drawn and show the way organic chemists graphically depict reactions. It uses a combination of basic valence bond pictures with more sophisticated molecular orbital treatments. It handles mechanisms both from the "electron pushing perspective" and from a kinetic and energetic view. The book will be very useful to new US graduate students and will help bring them to the level of sophistication needed to be serious researchers in organic chemistry." Charles P. Casey, University of Wisconsin-Madison "This is an excellent advanced organic chemistry textbook that provides a key resource for students and teachers alike." Mark Rizzacasa, University of Melbourne, Australia.

Organic Reactions Stereochemistry And Mechanism (Through Solved Problems)

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Author: P S Kalsi

Publisher: New Age International

ISBN: 9788122417661

Category: Physical organic chemistry

Page: 608

View: 2627

The Book Provides A Self-Study Of Different Topics Of Organic Chemistry Viab Problem Solving. The Present 4Th Edition Has Been Completely Rewritten According To The Organic Chemistry Syllabus Of The Net (Csir) Examination. This Necessitated The Deletion Of Several Topics From The Third Edition And Incorporation Of New Ones. Emphasis Has Been Laid On A Variety Of New Reactions, Name Reactions, Reagents In Organic Synthesis And Incorporation Of Their Knowledge In The Entire Coverage Of Organic Chemistry In A Unique Way.A Thorough Study Of The Book Is Expected To Help The Student To Excel Not Only In The University Examination Including The Net Examination, But Also In His Learning Of Various Topics And Before Interview Boards. Several Topics Like Aromaticity, Pericyclic Reactions And Heterocyclic Chemistry Have Now Been Brought Up To Date And The Material Provided Is Complete In Itself.The Presentation Has Been So Designed So As To Thread Through The Entire Organic Chemistry By The Application Of The Knowledge Learnt In One Topic To Newer Situations In Other Topics. The Present Revised Edition Also Includes Numerous Important Developments Since The Third Edition Of The Book Was Published.

Die systematische Nomenklatur der Organischen Chemie

Eine Gebrauchsanweisung

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Author: D. Hellwinkel

Publisher: Springer-Verlag

ISBN: 3662066866

Category: Science

Page: 172

View: 4702

So soll diese Übersicht helfen, von der Formel zum Namen und vom Namen zur Formel zu führen. Sie wendet sich dabei nicht nur an die Chemiker, sondern möchte auch Medizinern, Biologen und anderen, die mit der Organischen Chemie zusammentreffen, das Verständnis der Literatur er leichtem. D. Hellwinkel Vorwort zur zweiten Auflage Nachdem die erste Auflage schnell vergriffen war, wurden bei dieser neu durchgesehenen, korrigierten Auflage auch einige neuere Entwicklungen bei der Schreibweise chemi scher Namen berücksichtigt. Heidelberg, im März 1978 Der Veifasser Inhalt Einleitung . 1 Literatur . 4 1. Stammsysteme 1. 1. Acyclische Kohlenwasserstoff-Systeme 5 1. 2. Cyclische Systeme . . . . . . . . . 11 1. 2. 1. Cyclische Kohlenwasserstoff-Systeme . 11 1. 2. 1. 1. Monocyclische Kohlenwasserstoffe . . 11 1. 2. 1. 2. Polycyclische Kohlenwasserstoffe . . 12 1. 2. 1. 2. 1. Kondensierte polycyclische Kohlenwasserstoffe 12 1. 2. 1. 2. 2. Verbrückte polycyclische Kohlenwasserstoffe . 23 1. 2. 1. 2. 3. Spiro-Kohlenwasserstoffe . . . . . . . . . . 28 1. 2. 1. 2. 4. Kohlenwasserstoff-Ringsysteme, die über Einfa- oder Doppelbindungen miteinander verknüpft sind 32 1. 2. 1. 2. 5. Cyclische Kohlenwasserstoffe mit Seitenketten . 34 1. 2. i. · Heterocyclische Systeme . . . . . . . . . . 36 1. 2. 2. 1. Trivialnamen . . . . . . . . . . . . . . . 36 1. 2. 2. 2. Ersetzungsnomenklatur (sog. "a"-Nomenklatur) 44 1. 2. 2. 3. Das Hantzsch-Widman-Patterson-System 46 2. Substituierte Systeme 2. 1. Allgemeine Vorbemerkungen . . . . . . . 59 2. 2. Nomenklaturtypen für substituierte Systeme 60 2. 2. 1. Die substitutive Nomenklatur . . . . 60 2. 2. 2. Die radikofunktionelle Nomenklatur . 67 2. 2. 3. Die additive Nomenklatur . . 68 2. 2. 4. Die subtraktive Nomenklatur . . . . 70 2. 2. 5. Die konjunktive Nomenklatur . . .

Organic Chemistry

A Mechanistic Approach

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Author: Tadashi Okuyama,Howard Maskill

Publisher: Oxford University Press

ISBN: 0199693277

Category: Juvenile Nonfiction

Page: 648

View: 7931

Organic Chemistry: A mechanistic approach combines a focus on core topics and themes with a mechanistic approach to the explanation of the reactions it describes, making it ideal for those looking for a solid understanding of the central themes of organic chemistry.

Advanced Organic Chemistry

Part A: Structure and Mechanisms

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Author: Francis A. Carey,Richard J. Sundberg

Publisher: Springer Science & Business Media

ISBN: 9780387448978

Category: Science

Page: 1203

View: 3751

The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part A covers fundamental structural topics and basic mechanistic types. It can stand-alone; together, with Part B: Reaction and Synthesis, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for study of structure, reaction and selectivity for students and exercise solutions for instructors.

How To Solve Organic Reaction Mechanisms

A Stepwise Approach

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Author: Mark G. Moloney

Publisher: John Wiley & Sons

ISBN: 1118698517

Category: Science

Page: 240

View: 9689

How To Solve Organic Reaction Mechanisms: A Stepwise Approach is an upgraded and much-expanded sequel to the bestselling text Reaction Mechanisms at a Glance. This book takes a unique approach to show that a general problem-solving strategy is applicable to many of the common reactions of organic chemistry, demonstrating that logical and stepwise reasoning, in combination with a good understanding of the fundamentals, is a powerful tool to apply to the solution of problems. Sub-divided by functional group, the book uses a check-list approach to problem-solving using mechanistic organic chemistry as its basis. Each mechanistic problem is presented as a two-page spread; the left-hand page introduces the problem and provides a stepwise procedure for working through the reaction mechanisms, with helpful hints about the underlying chemistry. The right-hand page contains the full worked solution and summary. This revised edition includes the following updates: A new chapter which applies the problem solving strategy to ligand coupling reactions using transition metals Much-expanded set of fully worked problems Over 40 further problems (with answers for tutors) for use in tutorials How To Solve Organic Reaction Mechanisms: A Stepwise Approach is an essential workbook for all students studying organic chemistry, and a useful aide for teachers of undergraduate organic chemistry to use in their tutorials.

Reaction Mechanisms in Environmental Organic Chemistry

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Author: Richard A. Larson,Eric J. Weber

Publisher: CRC Press

ISBN: 9780873712583

Category: Science

Page: 448

View: 5503

Reaction Mechanisms in Environmental Organic Chemistry classifies and organizes the reactions of environmentally important organic compounds using concepts and data drawn from traditional mechanistic and physical organic chemistry. It will help readers understand these reactions and their importance for the environmental fates or organic compounds of many types. The book has a molecular and mechanistic emphasis, and it is organized by reaction type. Organic molecules and their fates are examined in an ecosystem context. Their reactions are discussed in terms that organic chemists would use. The book will benefit organic chemists, environmental engineers, water treatment professionals, hazardous waste specialists, and biologists. Although conceived as a comprehensive monograph, the book could also be used as a text or reference for environmental chemistry classes at the undergraduate or graduate level.