Linear and Generalized Linear Mixed Models and Their Applications

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Author: Jiming Jiang

Publisher: Springer Science & Business Media

ISBN: 0387479465

Category: Mathematics

Page: 257

View: 6503

This book covers two major classes of mixed effects models, linear mixed models and generalized linear mixed models. It presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. The book offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it includes recently developed methods, such as mixed model diagnostics, mixed model selection, and jackknife method in the context of mixed models. The book is aimed at students, researchers and other practitioners who are interested in using mixed models for statistical data analysis.

Correlated Data Analysis: Modeling, Analytics, and Applications

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Author: Xue-Kun Song

Publisher: Springer Science & Business Media

ISBN: 0387713921

Category: Mathematics

Page: 346

View: 6910

This book covers recent developments in correlated data analysis, using the class of dispersion models as marginal components in the formulation of joint models for correlated data. Much new material is covered here that you won’t find elsewhere.

Correlated Data Analysis: Modeling, Analytics, and Applications

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Author: Peter X. -K. Song

Publisher: Springer Science & Business Media

ISBN: 038771393X

Category: Mathematics

Page: 352

View: 9300

This book covers recent developments in correlated data analysis. It utilizes the class of dispersion models as marginal components in the formulation of joint models for correlated data. This enables the book to cover a broader range of data types than the traditional generalized linear models. The reader is provided with a systematic treatment for the topic of estimating functions, and both generalized estimating equations (GEE) and quadratic inference functions (QIF) are studied as special cases. In addition to the discussions on marginal models and mixed-effects models, this book covers new topics on joint regression analysis based on Gaussian copulas.

Linear Models

Least Squares and Alternatives

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Author: Calyampudi R. Rao,Helge Toutenburg

Publisher: Springer Science & Business Media

ISBN: 0387227520

Category: Mathematics

Page: 429

View: 587

An up-to-date account of the theory and applications of linear models, for use as a textbook in statistics at graduate level as well as an accompanying text for other courses in which linear models play a part. The authors present a unified theory of inference from linear models with minimal assumptions, not only through least squares theory, but also using alternative methods of estimation and testing based on convex loss functions and general estimating equations. Highlights include: - a special emphasis on sensitivity analysis and model selection; - a chapter devoted to the analysis of categorical data based on logic, loglinear, and logistic regression models; - a chapter devoted to incomplete data sets; - an extensive appendix on matrix theory; - a chapter devoted to the analysis of categorical data based on a unified presentation of generalized linear models including GEE-methods for correlated response; - a chapter devoted to incomplete data sets including regression diagnostics to identify Non-MCAR-processes The material covered is thus invaluable not only to graduates, but also to researchers and consultants in statistics.

Vector Generalized Linear and Additive Models

With an Implementation in R

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Author: Thomas W. Yee

Publisher: Springer

ISBN: 149392818X

Category: Mathematics

Page: 589

View: 6628

This book presents a greatly enlarged statistical framework compared to generalized linear models (GLMs) with which to approach regression modelling. Comprising of about half-a-dozen major classes of statistical models, and fortified with necessary infrastructure to make the models more fully operable, the framework allows analyses based on many semi-traditional applied statistics models to be performed as a coherent whole. Since their advent in 1972, GLMs have unified important distributions under a single umbrella with enormous implications. However, GLMs are not flexible enough to cope with the demands of practical data analysis. And data-driven GLMs, in the form of generalized additive models (GAMs), are also largely confined to the exponential family. The methodology here and accompanying software (the extensive VGAM R package) are directed at these limitations and are described comprehensively for the first time in one volume. This book treats distributions and classical models as generalized regression models, and the result is a much broader application base for GLMs and GAMs. The book can be used in senior undergraduate or first-year postgraduate courses on GLMs or categorical data analysis and as a methodology resource for VGAM users. In the second part of the book, the R package VGAM allows readers to grasp immediately applications of the methodology. R code is integrated in the text, and datasets are used throughout. Potential applications include ecology, finance, biostatistics, and social sciences. The methodological contribution of this book stands alone and does not require use of the VGAM package.

Linear Models with R, Second Edition

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Author: Julian J. Faraway

Publisher: CRC Press

ISBN: 1439887349

Category: Mathematics

Page: 286

View: 5659

A Hands-On Way to Learning Data Analysis Part of the core of statistics, linear models are used to make predictions and explain the relationship between the response and the predictors. Understanding linear models is crucial to a broader competence in the practice of statistics. Linear Models with R, Second Edition explains how to use linear models in physical science, engineering, social science, and business applications. The book incorporates several improvements that reflect how the world of R has greatly expanded since the publication of the first edition. New to the Second Edition Reorganized material on interpreting linear models, which distinguishes the main applications of prediction and explanation and introduces elementary notions of causality Additional topics, including QR decomposition, splines, additive models, Lasso, multiple imputation, and false discovery rates Extensive use of the ggplot2 graphics package in addition to base graphics Like its widely praised, best-selling predecessor, this edition combines statistics and R to seamlessly give a coherent exposition of the practice of linear modeling. The text offers up-to-date insight on essential data analysis topics, from estimation, inference, and prediction to missing data, factorial models, and block designs. Numerous examples illustrate how to apply the different methods using R.

Bayesian and Frequentist Regression Methods

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Author: Jon Wakefield

Publisher: Springer Science & Business Media

ISBN: 1441909257

Category: Mathematics

Page: 697

View: 5368

Bayesian and Frequentist Regression Methods provides a modern account of both Bayesian and frequentist methods of regression analysis. Many texts cover one or the other of the approaches, but this is the most comprehensive combination of Bayesian and frequentist methods that exists in one place. The two philosophical approaches to regression methodology are featured here as complementary techniques, with theory and data analysis providing supplementary components of the discussion. In particular, methods are illustrated using a variety of data sets. The majority of the data sets are drawn from biostatistics but the techniques are generalizable to a wide range of other disciplines.

Foundations of Linear and Generalized Linear Models

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Author: Alan Agresti

Publisher: John Wiley & Sons

ISBN: 1118730038

Category: Mathematics

Page: 472

View: 3075

"This book presents an overview of the foundations and the key ideas and results of linear and generalized linear models under one cover. Written by a prolific academic, researcher, and textbook writer, Foundations of Linear and Generalized Linear Modelsis soon to become the gold standard by which all existing textbooks on the topic will be compared. While the emphasis is clearly and succinctly on theoretical underpinnings, applications in "R" are presented when they help to elucidate the content or promote practical model building. Each chapter contains approximately 15-20 exercises, primarily for readers to practice and extend the theory, but, also to assimilate the ideas by doing some data analysis. The carefully crafted models and examples convey basic concepts and do not get mired down in non-trivial considerations. An author-maintained web site includes, among other numerous pedagogical supplements, analyses that parallel the "R" routines from the book in SAS, SPSS and Stata"--

Mixed Effects Models for the Population Approach

Models, Tasks, Methods and Tools

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Author: Marc Lavielle

Publisher: CRC Press

ISBN: 1482226502

Category: Mathematics

Page: 383

View: 5632

Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects Models Mixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models. With these models, readers can perform parameter estimation and modeling across a whole population of individuals at the same time. Easy-to-Use Techniques and Tools for Real-World Data Modeling The book first shows how the framework allows model representation for different data types, including continuous, categorical, count, and time-to-event data. This leads to the use of generic methods, such as the stochastic approximation of the EM algorithm (SAEM), for modeling these diverse data types. The book also covers other essential methods, including Markov chain Monte Carlo (MCMC) and importance sampling techniques. The author uses publicly available software tools to illustrate modeling tasks. Methods are implemented in Monolix, and models are visually explored using Mlxplore and simulated using Simulx. Careful Balance of Mathematical Representation and Practical Implementation This book takes readers through the whole modeling process, from defining/creating a parametric model to performing tasks on the model using various mathematical methods. Statisticians and mathematicians will appreciate the rigorous representation of the models and theoretical properties of the methods while modelers will welcome the practical capabilities of the tools. The book is also useful for training and teaching in any field where population modeling occurs.

Statistics for High-Dimensional Data

Methods, Theory and Applications

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Author: Peter Bühlmann,Sara van de Geer

Publisher: Springer Science & Business Media

ISBN: 364220192X

Category: Mathematics

Page: 558

View: 9398

Modern statistics deals with large and complex data sets, and consequently with models containing a large number of parameters. This book presents a detailed account of recently developed approaches, including the Lasso and versions of it for various models, boosting methods, undirected graphical modeling, and procedures controlling false positive selections. A special characteristic of the book is that it contains comprehensive mathematical theory on high-dimensional statistics combined with methodology, algorithms and illustrations with real data examples. This in-depth approach highlights the methods’ great potential and practical applicability in a variety of settings. As such, it is a valuable resource for researchers, graduate students and experts in statistics, applied mathematics and computer science.

Linear Mixed Models for Longitudinal Data

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Author: Geert Verbeke,Geert Molenberghs

Publisher: Springer Science & Business Media

ISBN: 1441903003

Category: Mathematics

Page: 570

View: 4203

This book provides a comprehensive treatment of linear mixed models for continuous longitudinal data. Next to model formulation, this edition puts major emphasis on exploratory data analysis for all aspects of the model, such as the marginal model, subject-specific profiles, and residual covariance structure. Further, model diagnostics and missing data receive extensive treatment. Sensitivity analysis for incomplete data is given a prominent place. Most analyses were done with the MIXED procedure of the SAS software package, but the data analyses are presented in a software-independent fashion.

Mixed-Effects Models in S and S-PLUS

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Author: José C. Pinheiro,Douglas Bates

Publisher: Springer Science & Business Media

ISBN: 1441903178

Category: Computers

Page: 530

View: 2215

R, linear models, random, fixed, data, analysis, fit.

Linear Mixed-Effects Models Using R

A Step-by-Step Approach

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Author: Andrzej Gałecki,Tomasz Burzykowski

Publisher: Springer Science & Business Media

ISBN: 1461439000

Category: Mathematics

Page: 542

View: 6482

Linear mixed-effects models (LMMs) are an important class of statistical models that can be used to analyze correlated data. Such data are encountered in a variety of fields including biostatistics, public health, psychometrics, educational measurement, and sociology. This book aims to support a wide range of uses for the models by applied researchers in those and other fields by providing state-of-the-art descriptions of the implementation of LMMs in R. To help readers to get familiar with the features of the models and the details of carrying them out in R, the book includes a review of the most important theoretical concepts of the models. The presentation connects theory, software and applications. It is built up incrementally, starting with a summary of the concepts underlying simpler classes of linear models like the classical regression model, and carrying them forward to LMMs. A similar step-by-step approach is used to describe the R tools for LMMs. All the classes of linear models presented in the book are illustrated using real-life data. The book also introduces several novel R tools for LMMs, including new class of variance-covariance structure for random-effects, methods for influence diagnostics and for power calculations. They are included into an R package that should assist the readers in applying these and other methods presented in this text.

Models for Discrete Longitudinal Data

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Author: Geert Molenberghs,Geert Verbeke

Publisher: Springer Science & Business Media

ISBN: 9780387251448

Category: Mathematics

Page: 683

View: 4924

This book provides a comprehensive treatment on modeling approaches for non-Gaussian repeated measures, possibly subject to incompleteness. The authors begin with models for the full marginal distribution of the outcome vector. This allows model fitting to be based on maximum likelihood principles, immediately implying inferential tools for all parameters in the models. At the same time, they formulate computationally less complex alternatives, including generalized estimating equations and pseudo-likelihood methods. They then briefly introduce conditional models and move on to the random-effects family, encompassing the beta-binomial model, the probit model and, in particular the generalized linear mixed model. Several frequently used procedures for model fitting are discussed and differences between marginal models and random-effects models are given attention The authors consider a variety of extensions, such as models for multivariate longitudinal measurements, random-effects models with serial correlation, and mixed models with non-Gaussian random effects. They sketch the general principles for how to deal with the commonly encountered issue of incomplete longitudinal data. The authors critique frequently used methods and propose flexible and broadly valid methods instead, and conclude with key concepts of sensitivity analysis. Without putting too much emphasis on software, the book shows how the different approaches can be implemented within the SAS software package. The text is organized so the reader can skip the software-oriented chapters and sections without breaking the logical flow. Geert Molenberghs is Professor of Biostatistics at the Universiteit Hasselt in Belgium and has published methodological work on surrogate markers in clinical trials, categorical data, longitudinal data analysis, and the analysis of non-response in clinical and epidemiological studies. He served as Joint Editor for Applied Statistics (2001–2004) and as Associate Editor for several journals, including Biometrics and Biostatistics. He was President of the International Biometric Society (2004–2005). He was elected Fellow of the American Statistical Association and received the Guy Medal in Bronze from the Royal Statistical Society. Geert Verbeke is Professor of Biostatistics at the Biostatistical Centre of the Katholieke Universiteit Leuven in Belgium. He has published a number of methodological articles on various aspects of models for longitudinal data analyses, with particular emphasis on mixed models. Geert Verbeke is Past President of the Belgian Region of the International Biometric Society, International Program Chair for the International Biometric Conference in Montreal (2006), and Joint Editor of the Journal of the Royal Statistical Society, Series A (2005–2008). He has served as Associate Editor for several journals including Biometrics and Applied Statistics. The authors also wrote a monograph on linear mixed models for longitudinal data (Springer, 2000) and received the American Statistical Association's Excellence in Continuing Education Award, based on short courses on longitudinal and incomplete data at the Joint Statistical Meetings of 2002 and 2004.

Statistical Models in Epidemiology, the Environment, and Clinical Trials

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Author: M.Elizabeth Halloran,Donald Berry

Publisher: Springer Science & Business Media

ISBN: 9780387989242

Category: Medical

Page: 283

View: 2705

This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. I am grateful to Seymour Geisser of University of Minnesota (Statistics), Patricia Grambsch, University of Minnesota (Biostatistics); Joel Greenhouse, Carnegie Mellon University (Statistics); Nicholas Lange, Harvard Medical School (Brain Imaging Center, McLean Hospital); Barry Margolin, University of North Carolina-Chapel Hill (Biostatistics); Sandy Weisberg, University of Minnesota (Statistics); Scott Zeger, Johns Hop kins University (Biostatistics); and Marvin Zelen, Harvard School of Public Health (Biostatistics) for organizing the six weeks summer program. I also take this opportunity to thank the National Science Foundation (NSF) and the Army Research Office (ARO), whose financial support made the workshop possible. Willard Miller, Jr.

Applied Regression Analysis and Generalized Linear Models

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Author: John Fox

Publisher: SAGE Publications

ISBN: 1483321312

Category: Social Science

Page: 816

View: 5177

Combining a modern, data-analytic perspective with a focus on applications in the social sciences, the Third Edition of Applied Regression Analysis and Generalized Linear Models provides in-depth coverage of regression analysis, generalized linear models, and closely related methods, such as bootstrapping and missing data. Updated throughout, this Third Edition includes new chapters on mixed-effects models for hierarchical and longitudinal data. Although the text is largely accessible to readers with a modest background in statistics and mathematics, author John Fox also presents more advanced material in optional sections and chapters throughout the book.

A Primer on Linear Models

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Author: John F. Monahan

Publisher: CRC Press

ISBN: 9781420062045

Category: Mathematics

Page: 304

View: 521

A Primer on Linear Models presents a unified, thorough, and rigorous development of the theory behind the statistical methodology of regression and analysis of variance (ANOVA). It seamlessly incorporates these concepts using non-full-rank design matrices and emphasizes the exact, finite sample theory supporting common statistical methods. With coverage steadily progressing in complexity, the text first provides examples of the general linear model, including multiple regression models, one-way ANOVA, mixed-effects models, and time series models. It then introduces the basic algebra and geometry of the linear least squares problem, before delving into estimability and the Gauss–Markov model. After presenting the statistical tools of hypothesis tests and confidence intervals, the author analyzes mixed models, such as two-way mixed ANOVA, and the multivariate linear model. The appendices review linear algebra fundamentals and results as well as Lagrange multipliers. This book enables complete comprehension of the material by taking a general, unifying approach to the theory, fundamentals, and exact results of linear models.

Explanatory Item Response Models

A Generalized Linear and Nonlinear Approach

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Author: Paul de Boeck,Mark Wilson

Publisher: Springer Science & Business Media

ISBN: 1475739907

Category: Social Science

Page: 382

View: 2459

This edited volume gives a new and integrated introduction to item response models (predominantly used in measurement applications in psychology, education, and other social science areas) from the viewpoint of the statistical theory of generalized linear and nonlinear mixed models. It also includes a chapter on the statistical background and one on useful software.

Multivariate Generalized Linear Mixed Models Using R

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Author: Damon Mark Berridge,Robert Crouchley

Publisher: CRC Press

ISBN: 1439813272

Category: Mathematics

Page: 304

View: 8191

Multivariate Generalized Linear Mixed Models Using R presents robust and methodologically sound models for analyzing large and complex data sets, enabling readers to answer increasingly complex research questions. The book applies the principles of modeling to longitudinal data from panel and related studies via the Sabre software package in R. A Unified Framework for a Broad Class of Models The authors first discuss members of the family of generalized linear models, gradually adding complexity to the modeling framework by incorporating random effects. After reviewing the generalized linear model notation, they illustrate a range of random effects models, including three-level, multivariate, endpoint, event history, and state dependence models. They estimate the multivariate generalized linear mixed models (MGLMMs) using either standard or adaptive Gaussian quadrature. The authors also compare two-level fixed and random effects linear models. The appendices contain additional information on quadrature, model estimation, and endogenous variables, along with SabreR commands and examples. Improve Your Longitudinal Study In medical and social science research, MGLMMs help disentangle state dependence from incidental parameters. Focusing on these sophisticated data analysis techniques, this book explains the statistical theory and modeling involved in longitudinal studies. Many examples throughout the text illustrate the analysis of real-world data sets. Exercises, solutions, and other material are available on a supporting website.

Advances in Statistical Methods for Genetic Improvement of Livestock

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Author: Daniel Gianola,Keith Hammond

Publisher: Springer Science & Business Media

ISBN: 3642744877

Category: Technology & Engineering

Page: 534

View: 365

Developments in statistics and computing as well as their application to genetic improvement of livestock gained momentum over the last 20 years. This text reviews and consolidates the statistical foundations of animal breeding. This text will prove useful as a reference source to animal breeders, quantitative geneticists and statisticians working in these areas. It will also serve as a text in graduate courses in animal breeding methodology with prerequisite courses in linear models, statistical inference and quantitative genetics.