Genomic Control Process

Development and Evolution

DOWNLOAD NOW »

Author: Isabelle Peter,Eric H. Davidson

Publisher: Academic Press

ISBN: 0124047467

Category: Science

Page: 460

View: 1106

Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type Demonstrates the causal power of system-level understanding of genomic control process Conceptually organizes a constellation of complex and diverse biological phenomena Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome

The Regulatory Genome

Gene Regulatory Networks In Development And Evolution

DOWNLOAD NOW »

Author: Eric H. Davidson

Publisher: Elsevier

ISBN: 9780080455570

Category: Science

Page: 304

View: 3519

Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams

Chordate Origins and Evolution

The Molecular Evolutionary Road to Vertebrates

DOWNLOAD NOW »

Author: Noriyuki Satoh

Publisher: Academic Press

ISBN: 0128030062

Category: Science

Page: 220

View: 9661

Chordate Origins and Evolution: The Molecular Evolutionary Road to Vertebrates focuses on echinoderms (starfish, sea urchins, and others), hemichordates (acorn worms, etc.), cephalochordates (lancelets), urochordates or tunicates (ascidians, larvaceans and others), and vertebrates. In general, evolution of these groups is discussed independently, on a larger scale: ambulacrarians (echi+hemi) and chordates (cephlo+uro+vert). Until now, discussion of these topics has been somewhat fragmented, and this work provides a unified presentation of the essential information. In the more than 150 years since Charles Darwin proposed the concept of the origin of species by means of natural selection, which has profoundly affected all fields of biology and medicine, the evolution of animals (metazoans) has been studied, discussed, and debated extensively. Following many decades of classical comparative morphology and embryology, the 1980s marked a turning point in studies of animal evolution, when molecular biological approaches, including molecular phylogeny (MP), molecular evolutionary developmental biology (evo-devo), and comparative genomics (CG), began to be employed. There are at least five key events in metazoan evolution, which include the origins of 1) diploblastic animals, such as cnidarians; 2) triploblastic animals or bilaterians; 3) protostomes and deuterostomes; 4) chordates, among deuterostomes; and 5) vertebrates, among chordates. The last two have received special attention in relation to evolution of human beings. During the past two decades, great advances have been made in this field, especially in regard to molecular and developmental mechanisms involved in the evolution of chordates. For example, the interpretation of phylogenetic relationships among deuterostomes has drastically changed. In addition, we have now obtained a large quantity of MP, evo-devo, and CG information on the origin and evolution of chordates. Covers the most significant advances in this field to give readers an understanding of the interesting biological issues involved Provides a unified presentation of essential information regarding each phylum and an integrative understanding of molecular mechanisms involved in the origin and evolution of chordates Discusses the evolutionary scenario of chordates based on two major characteristic features of animals—namely modes of feeding (energy sources) and reproduction—as the two main forces driving animal evolution and benefiting dialogue for future studies of animal evolution

Philosophy of Systems Biology

Perspectives from Scientists and Philosophers

DOWNLOAD NOW »

Author: Sara Green

Publisher: Springer

ISBN: 3319470000

Category: Science

Page: 265

View: 929

The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society. The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead. Readers are invited to engage with different views on the questions addressed, and may explore numerous themes relating to the philosophy of systems biology. This edited work will appeal to scholars and all levels, from undergraduates to researchers, and to those interested in a variety of scholarly approaches such as systems biology, mathematical and computational modelling, cell and molecular biology, genomics, systems theory, and of course, philosophy of biology.

Das egoistische Gen

Mit einem Vorwort von Wolfgang Wickler

DOWNLOAD NOW »

Author: Richard Dawkins

Publisher: Springer-Verlag

ISBN: 3642553915

Category: Science

Page: 489

View: 5557

p”Ein auch heute noch bedeutsamer Klassiker“ Daily Express Sind wir Marionetten unserer Gene? Nach Richard Dawkins ́ vor über 30 Jahren entworfener und heute noch immer provozierender These steuern und dirigieren unsere von Generation zu Generation weitergegebenen Gene uns, um sich selbst zu erhalten. Alle biologischen Organismen dienen somit vor allem dem Überleben und der Unsterblichkeit der Erbanlagen und sind letztlich nur die "Einweg-Behälter" der "egoistischen" Gene. Sind wir Menschen also unserem Gen-Schicksal hilflos ausgeliefert? Dawkins bestreitet dies und macht uns Hoffnung: Seiner Meinung nach sind wir nämlich die einzige Spezies mit der Chance, gegen ihr genetisches Schicksal anzukämpfen.

Essence in the Age of Evolution

A New Theory of Natural Kinds

DOWNLOAD NOW »

Author: Christopher J. Austin

Publisher: Routledge

ISBN: 1351240838

Category: Philosophy

Page: 144

View: 6227

This book offers a novel defence of a highly contested philosophical position: biological natural kind essentialism. This theory is routinely and explicitly rejected for its purported inability to be explicated in the context of contemporary biological science, and its supposed incompatibility with the process and progress of evolution by natural selection. Christopher J. Austin challenges these objections, and in conjunction with contemporary scientific advancements within the field of evolutionary-developmental biology, the book utilises a contemporary neo-Aristotelian metaphysics of "dispositional properties", or causal powers, to provide a theory of essentialism centred on the developmental architecture of organisms and its role in the evolutionary process. By defending a novel theory of Aristotelian biological natural kind essentialism, Essence in the Age of Evolution represents the fresh and exciting union of cutting-edge philosophical insight and scientific knowledge.

Essays on Developmental Biology

DOWNLOAD NOW »

Author: N.A

Publisher: Academic Press

ISBN: 0128029765

Category: Science

Page: 770

View: 8481

In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or “golden anniversary. To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016. The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world. Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms. Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical. Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come. Covers the area of developmental processes for a variety of model organisms International board of authors Part of two 50th Anniversary volumes proving a comprehensive set of reviews edited by Serial Editor Paul M. Wassarman

Raub, Sex, Mord Und Schuster Voigt

Krasse Strafprozesse Aus Dem Wilhelminischen Kaiserreich

DOWNLOAD NOW »

Author: Hugo Friedlaender,Hermann Syzygos

Publisher: CreateSpace

ISBN: 9781500294762

Category: True Crime

Page: 352

View: 9204

Im Sommer 1890 wurden zwei junge Mädchen, die den Kreisen der besseren Gesellschaft angehörten, von ihren Angehörigen vermisst. Man wusste, dass sie sich infolge einer chiffrierten Zeitungsannonce als Reisebegleiterinnen gemeldet hatten, man konnte aber ihr Verschwinden trotz aller Bemühungen nicht erklären.(...)Vorsitzender: "Ihre Wirtin in Osnabrück hat erzählt: Sie haben des Nachts häufig geweint?"Die Angeklagte Buntrock: "Das geschah wegen des vielen Totmachens." (Aus dem Buntrock-Erbe-Prozess.)Dieser Band mit authentischen Berichten aus der wilhelminischen Ära dokumentiert auch unblutige Prozesse wie den gegen Schuster Wilhelm Voigt alias "Hauptmann von Köpenick" oder jenen gegen das angebliche "spiritistische Medium" Anna Rothe. Sex kannten unsere Vorfahren auch, denn sonst wären wir ja ausgestorben. Allerdings ist dieses Buch kein Porno, sondern ein interessantes und teilweise kurioses Zeitdokument.Die über hundert Jahre alten Texte wurden vom Herausgeber durchgesehen, lesefreundlich bearbeitet, in sinnvolle Absätze untergliedert und der neuen Rechtschreibung angepasst.

The Eukaryote Genome in Development and Evolution

DOWNLOAD NOW »

Author: John Bernard

Publisher: Springer Science & Business Media

ISBN: 9401159912

Category: Science

Page: 416

View: 2316

'The mind unlearns with difficulty what has long been impressed upon it. ' Seneca Reductionism, is, without question, the most successful analytical approach available to the experimental scientist. With the advent of techniques for cloning and sequencing DNA, and the development of a variety of molecular probes for localizing macromolecules in cells and tissues, the biologist now has available the most powerful reductionist tools ever invented. The application of these new technologies has led to a veritable explosion of facts regarding the types and organization of nucleotide sequences present in the genomes of eukaryotes. These data offer a level of precision and predictability which is unparalleled in biology. Recombinant DNA techniques were initially developed to gather information about the structure and organization of the DNA sequences within a genome. The power and potential of these techniques, however, extend far beyond simple data collection of this kind. In an attempt to use the new technology as a basis for analyzing development and evolution, attention was first focused on the topic of gene regulation, an approach that had proven so successful in prokaryotes. It is now clear that this has not been an adequate approach. Lewin (1984) has quoted Brenner as stating 'at the beginning it was said that the answer to the understanding of development was going to come from a knowledge of the molecular mechanisms of gene control. I doubt whether anyone believes this any more.

Evolution

eine Einführung

DOWNLOAD NOW »

Author: Brian Charlesworth,Deborah Charlesworth

Publisher: N.A

ISBN: 9783150187050

Category:

Page: 211

View: 4026

Evolution auf den Punkt gebracht. Eine kurze Einführung in die Prinzipien und Fragen der Entstehung und Entwicklung des Lebens auf unserem Planeten.

Blattschneiderameisen – der perfekte Superorganismus

DOWNLOAD NOW »

Author: Bert Hölldobler,Edward O. Wilson

Publisher: Springer

ISBN: 9783642167041

Category: Science

Page: 166

View: 8734

Blattschneiderameisen herrschen über Wälder, Wiesen und Ackerland – von Louisiana bis Patagonien. Jede Ameisen-Kolonie umfasst fast fünf Millionen Arbeiterinnen, alles Töchter einer einzigen Königin. Ihr Nest kann sich auf eine Länge von bis zu knapp 10 Meter erstrecken, bestehend aus Hunderten von Kammern. Das weltberühmte Autorenduo liefert mit dem Band die detaillierteste Beschreibung einer Ameisenspezies, die es je gab. Das mit exzellenten Fotos versehene Werk wendet sich sowohl an gebildete Laien als auch an ein wissenschaftliches Publikum.

Evolutionary Developmental Biology

DOWNLOAD NOW »

Author: Brian K. Hall

Publisher: Springer Science & Business Media

ISBN: 9780412785900

Category: Science

Page: 491

View: 6709

Although evolutionary developmental biology is a new field, its origins lie in the last century; the search for connections between embryonic development (ontogeny) and evolutionary change (phylogeny) has been a long one. Evolutionary developmental biology is however more than just a fusion of the fields of developmental and evolutionary biology. It forges a unification of genomic, developmental, organismal, population and natural selection approaches to evolutionary change. It is concerned with how developmental processes evolve; how evolution produces novel structures, functions and behaviours; and how development, evolution and ecology are integrated to bring about and stabilize evolutionary change. The previous edition of this title, published in 1992, defined the terms and laid out the field for evolutionary developmental biology. This field is now one of the most active and fast growing within biology and this is reflected in this second edition, which is more than twice the length of the original and brought completely up to date. There are new chapters on major transitions in animal evolution, expanded coverage of comparative embryonic development and the inclusion of recent advances in genetics and molecular biology. The book is divided into eight parts which: place evolutionary developmental biology in the historical context of the search for relationships between development and evolution; detail the historical background leading to evolutionary embryology; explore embryos in development and embryos in evolution; discuss the relationship between embryos, evolution, environment and ecology; discuss the dilemma for homology of the fact that development evolves; deal with the importance of understanding how embryos measure time and place both through development and evolutionarily through heterochrony and heterotrophy; and set out the principles and processes that underlie evolutionary developmental biology. With over one hundred illustrations and photographs, extensive cross-referencing between chapters and boxes for ancillary material, this latest edition will be of immense interest to graduate and advanced undergraduate students in cell, developmental and molecular biology, and in zoology, evolution, ecology and entomology; in fact anyone with an interest in this new and increasingly important and interdisciplinary field which unifies biology.

Genome Evolution

Gene and Genome Duplications and the Origin of Novel Gene Functions

DOWNLOAD NOW »

Author: Axel Meyer,Yves van de Peer

Publisher: Springer Science & Business Media

ISBN: 9781402010217

Category: Medical

Page: 237

View: 3120

In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation. This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.

Genomic Regulatory Systems

In Development and Evolution

DOWNLOAD NOW »

Author: Eric H. Davidson

Publisher: Elsevier

ISBN: 9780080525594

Category: Science

Page: 261

View: 4981

The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest. The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist. * Contents Include * Regulatory Hardwiring: A Brief Overview of the Genomic Control Apparatus and Its Causal Role in Development and Evolution * Inside the Cis-Regulatory Module: Control Logic and How the Regulatory Environment Is Transduced into Spatial Patterns of Gene Expression * Regulation of Direct Cell-Type Specification in Early Development * The Secret of the Bilaterians: Abstract Regulatory Design in Building Adult Body Parts * Changes That Make New Forms: Gene Regulatory Systems and the Evolution of Body Plans

Gentechnologie für Einsteiger

DOWNLOAD NOW »

Author: T. A. Brown

Publisher: Spektrum Akademischer Verlag

ISBN: 9783827428684

Category: Science

Page: 298

View: 8993

Gentechnologie für Einsteiger hat sich weltweit als leicht verständliche Einführung in dieses wichtige und spannende Wissenschaftsgebiet bewährt. Die sechste Auflage bleibt dem Grundkonzept früherer Auflagen treu, widmet sich aber auch neuen, wachsenden Forschungsfeldern. Das Buch bleibt damit ein unentbehrlicher Leitfaden für Studierende in den Biowissenschaften und ihren zahlreichen Teilgebieten. Es eignet sich auch bestens als Einführung für alle, die sich in ihrem Beruf mit den Grundlagen des Themas vertraut machen müssen.

Die Metamorphose der Pflanzen

DOWNLOAD NOW »

Author: Johann Wolfgang Goethe

Publisher: BoD – Books on Demand

ISBN: 3843090378

Category: Art

Page: 44

View: 3150

Johann Wolfgang Goethe: Die Metamorphose der Pflanzen Entstanden 1790. Erstdruck: Gotha (C.W. Ettinger) 1790, dann wieder in: Zur Morphologie, 1817. Neuausgabe. Herausgegeben von Karl-Maria Guth. Berlin 2016. Umschlaggestaltung von Thomas Schultz-Overhage unter Verwendung des Bildes: Joseph Karl Stieler, Johann Wolfgang von Goethe im 80. Lebensjahr, 1828. Gesetzt aus der Minion Pro, 11 pt.