Classics in Total Synthesis II

More Targets, Strategies, Methods

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Author: K. C. Nicolaou

Publisher: Wiley-VCH

ISBN: 9783527306848

Category: Science

Page: 639

View: 4116

Classics in Total Synthesis II is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed second volume, K.C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21st century. While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advance in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of our time. Key features include: Systematically develops domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis through the chosen synthesis Discusses cutting edge synthetic technologies in terms of mechanism and scope Presents new reactions, such as olefin metathesis, in mini-review style Includes abundant references for further reading CD with useful teaching material for lecturers is included with hardback version (ISBN 3-527-30685-4) Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis. From the reviews: "... a volume, (...) which any chemist with an interest in synthetic organic chemistry will wish to acquire." –JACS (on the previous volume) "...this superb book (...) will be an essential purchase for many organic chemists." –Nature (on the previous volume) "...Classics II is undoubtedly an excellent bargain that is highly recommended to everybody interested in advanced organic chemistry. One of my co-workers confessed that Classics I was the book on his bedside table while he prepared his thesis defense. Isn't that the highest distinction for a monograph? I have every reason to believe that Classics II will equally stand the selection process by students (and probably their supervisors too)." –Angewandte Chemie, 2004 "Well, there is a new pleasant read for the advanced student and even the experienced. It is the second volume to the established Classics in Total Synthesis and it continues the series extremely well." –ChemBioChem, 2004 "...the real innovation of this volume is the inclusion of alternative pathways to the same target molecule by other researchers. This enables the reader to appreciate that there are also other solutions to certain structural problems than those of the original synthesis. ... Let us hope that K. C. Nicolaou and his associates will present us with these future achievements in the same clear, informative and innovative format they have with the previous two volumes." –Applied Organometallic Chemistry

Supramolecular Chemistry

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Author: N.A

Publisher: Academic Press

ISBN: 0128151102

Category: Science

Page: 452

View: 2914

Supramolecular Chemistry, Volume 71, the latest release in the Advances in Inorganic Chemistry series presents timely and informative summaries on the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the field, serving as an indispensable reference to advanced researchers. In this volume, concise, authoritative reviews provide an up-to-date resource material for new investigators and established research personnel. Included references enable readers to pursue detail and development in each field. In addition, research chemists in other fields can use this serial to acquaint themselves with the latest experimental methods, techniques and computational applications within the field of inorganic reaction mechanisms. Features comprehensive reviews on the latest developments in supramolecular (complex) chemistry Includes contributions from leading experts in the field of supermolecules and related materials Serves as an indispensable reference to advanced researchers in supramolecular chemistry

Natural Products in Medicinal Chemistry

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Author: Stephen Hanessian

Publisher: John Wiley & Sons

ISBN: 3527676554

Category: Medical

Page: 652

View: 1129

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer

Domino Reactions in Organic Synthesis

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Author: Lutz F. Tietze,Gordon Brasche,Kersten Gericke

Publisher: John Wiley & Sons

ISBN: 3527608680

Category: Science

Page: 631

View: 9574

Domino reactions enable you to build complex structures in one-pot reactions without the need to isolate intermediates- a dream comes true. In this book, the well-respected expert, Professor Lutz Tietze, summarizes the possibilities of this reaction type - an approach for an efficiant, economically benificial and ecological benign synthesis. A definite must for every organic chemist.

Microscopy Applied to Materials Sciences and Life Sciences

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Author: Ajay Vasudeo Rane,Sabu Thomas,Nandakumar Kalarikkal

Publisher: CRC Press

ISBN: 1351251570

Category: Science

Page: 502

View: 8153

This new volume, Microscopy Applied to Materials Sciences and Life Sciences. focuses on recent theoretical and practical advances in polymers and their blends, composites, and nanocompos¬ites related to their microscopic characterization. It highlights recent accomplishments and trends in the field of polymer nanocomposites and filled polymers related to microstructural characterization. This book gives an insight and better understanding into the development in microscopy as a tool for characterization. The book emphasizes recent research work in the field of microscopy in life sciences and materials sciences mainly related to its synthesis, characterizations, and applications. The book explains the application of microscopic techniques in life sciences and materials sciences, and their applications and state of current research carried out. The book aims to foster a better understanding of the properties of polymer composites by describing new techniques to measure microstructure property relationships and by utilizing techniques and expertise developed in the conventional filled polymer composites. Characterization techniques, particularly microstructural characterization, have proven to be extremely difficult because of the range of length-scales associated with these materials. Topics include: •Instrumentation and Techniques: advances in scanning probe microscopy, SEM, TEM, OM. 3D imaging and tomography, electron diffraction techniques and analytical microscopy, advances in sample preparation techniques in-situ microscopy, correlative microscopy in life and material sciences, low voltage electron microscopy. •Life Sciences: Structure and imaging of biomolecules, live cell imaging, neurobiology, organelles and cellular dynamics, multi-disciplinary approaches for medical and biological sciences, microscopic application in plants, microorganism and environmental science, super resolution microscopy in biological sciences. •Materials Sciences: materials for nanotechnology, metals alloys and inter-metallic, ceramics, composites, minerals and microscopy in cultural heritage, thin films, coatings, surfaces and interfaces, carbon based materials, polymers and soft materials and self-assembled materials, semiconductors and magnetic materials. Polymers and inorganic nanoparticles. The volume will be of significant interest to scientists working on the basic issues surrounding polymers, nanocomposites, and nanoparticulate-filled polymers, as well as those working in industry on applied problems, such as processing. Because of the multidisciplinary nature of this research, the book will be valuable to chemists, materials scientists, physicists, chemical engineers, and processing specialists who are involved and interested in the future frontiers of blends.

Asymmetric Synthesis II

More Methods and Applications

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Author: Mathias Christmann,Stefan Bräse

Publisher: John Wiley & Sons

ISBN: 3527652264

Category: Science

Page: 400

View: 6105

Scientific Report

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Author: Scripps Research Institute

Publisher: N.A

ISBN: N.A

Category: Medicine

Page: 550

View: 2408

Journal

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Author: American Chemical Society

Publisher: N.A

ISBN: N.A

Category: Chemistry

Page: N.A

View: 6487

Strategies and Tactics in Organic Synthesis

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Author: Michael Harmata

Publisher: Academic Press

ISBN: 9780124502833

Category: Science

Page: 415

View: 2250

This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. It provides a window into the world of design, function and synthesis that is at the leading edge of the molecular frontier.

Physikalische Chemie

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Author: Peter W. Atkins,Julio de Paula,Michael Bär,Anna Schleitzer,Carsten Heinisch

Publisher: John Wiley & Sons

ISBN: 3527315462

Category: Science

Page: 1220

View: 4078

The Design of Everyday Things

Psychologie und Design der alltäglichen Dinge

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Author: Norman Don

Publisher: Vahlen

ISBN: 3800648105

Category: Business & Economics

Page: 320

View: 2142

Apple, Audi, Braun oder Samsung machen es vor: Gutes Design ist heute eine kritische Voraussetzung für erfolgreiche Produkte. Dieser Klassiker beschreibt die fundamentalen Prinzipien, um Dinge des täglichen Gebrauchs umzuwandeln in unterhaltsame und zufriedenstellende Produkte. Don Norman fordert ein Zusammenspiel von Mensch und Technologie mit dem Ziel, dass Designer und Produktentwickler die Bedürfnisse, Fähigkeiten und Handlungsweisen der Nutzer in den Vordergrund stellen und Designs an diesen angepasst werden. The Design of Everyday Things ist eine informative und spannende Einführung für Designer, Marketer, Produktentwickler und für alle an gutem Design interessierten Menschen. Zum Autor Don Norman ist emeritierter Professor für Kognitionswissenschaften. Er lehrte an der University of California in San Diego und der Northwest University in Illinois. Mitte der Neunzigerjahre leitete Don Norman die Advanced Technology Group bei Apple. Dort prägte er den Begriff der User Experience, um über die reine Benutzbarkeit hinaus eine ganzheitliche Erfahrung der Anwender im Umgang mit Technik in den Vordergrund zu stellen. Norman ist Mitbegründer der Beratungsfirma Nielsen Norman Group und hat unter anderem Autohersteller von BMW bis Toyota beraten. „Keiner kommt an Don Norman vorbei, wenn es um Fragen zu einem Design geht, das sich am Menschen orientiert.“ Brand Eins 7/2013 „Design ist einer der wichtigsten Wettbewerbsvorteile. Dieses Buch macht Spaß zu lesen und ist von größter Bedeutung.” Tom Peters, Co-Autor von „Auf der Suche nach Spitzenleistungen“

Forthcoming Books

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Author: Rose Arny

Publisher: N.A

ISBN: N.A

Category: American literature

Page: N.A

View: 9833

Der stumme Frühling

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Author: Rachel Carson

Publisher: C.H.Beck

ISBN: 3406704220

Category: Nature

Page: 348

View: 2556

Der stumme Frühling erschien erstmals 1962. Der Titel bezieht sich auf das eingangs erzählte Märchen von der blühenden Stadt, in der sich eine seltsame, schleichende Seuche ausbreitet … Das spannend geschriebene Sachbuch wirkte bei seinem Erscheinen wie ein Alarmsignal und avancierte rasch zur Bibel der damals entstehendenÖkologie-Bewegung. ZumerstenMal wurde hier in eindringlichem Appell die Fragwürdigkeit des chemischen Pflanzenschutzes dargelegt. An einer Fülle von Tatsachen machte Rachel Carson seine schädlichen Auswirkungen auf die Natur und die Menschen deutlich. Ihre Warnungen haben seither nichts von ihrer Aktualität verloren.

Die Katalyse

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Author: Paul Sabatier

Publisher: BoD – Books on Demand

ISBN: 3846039152

Category:

Page: 256

View: 1265