Bad Pharma

How Drug Companies Mislead Doctors and Harm Patients

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Author: Ben Goldacre

Publisher: Macmillan

ISBN: 0865478066

Category: Business & Economics

Page: 480

View: 4038

Argues that doctors are deliberately misinformed by profit-seeking pharmaceutical companies that casually withhold information about drug efficacy and side effects, explaining the process of pharmaceutical data manipulation and its global consequences. By the best-selling author of Bad Science.

Bad Pharma

How Drug Companies Mislead Doctors and Harm Patients

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Author: Ben Goldacre

Publisher: Fourth Estate

ISBN: 9780007498086

Category: Clinical trials

Page: 462

View: 1081

Following the bestselling 'Bad Science', which mercilessly exposed the evils of bogus, pseudo-scientific remedies, Ben Goldacre puts the global pharmaceutical industry under the microscope.

Bad Pharma: How Medicine is Broken, And How We Can Fix It

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Author: Ben Goldacre

Publisher: HarperCollins UK

ISBN: 0007363648

Category: Health & Fitness

Page: 448

View: 5729

Ben Goldacre puts the $600bn global pharmaceutical industry under the microscope. What he reveals is a fascinating, terrifying mess. ***Now updated with the latest government responses to the book***

Bad Science

Quacks, Hacks, and Big Pharma Flacks

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Author: Ben Goldacre

Publisher: McClelland & Stewart

ISBN: 0771035764

Category: Science

Page: 304

View: 4101

The informative and witty expose of the "bad science" we are all subjected to, called "one of the essential reads of the year" by New Scientist. We are obsessed with our health. And yet — from the media's "world-expert microbiologist" with a mail-order Ph.D. in his garden shed laboratory, and via multiple health scares and miracle cures — we are constantly bombarded with inaccurate, contradictory, and sometimes even misleading information. Until now. Ben Goldacre masterfully dismantles the questionable science behind some of the great drug trials, court cases, and missed opportunities of our time, but he also goes further: out of the bullshit, he shows us the fascinating story of how we know what we know, and gives us the tools to uncover bad science for ourselves. From the Hardcover edition.

Pharmageddon

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Author: David Healy

Publisher: Univ of California Press

ISBN: 0520275764

Category: Business & Economics

Page: 320

View: 8076

This searing indictment, David Healy’s most comprehensive and forceful argument against the pharmaceuticalization of medicine, tackles problems in health care that are leading to a growing number of deaths and disabilities. Healy, who was the first to draw attention to the now well-publicized suicide-inducing side effects of many anti-depressants, attributes our current state of affairs to three key factors: product rather than process patents on drugs, the classification of certain drugs as prescription-only, and industry-controlled drug trials. These developments have tied the survival of pharmaceutical companies to the development of blockbuster drugs, so that they must overhype benefits and deny real hazards. Healy further explains why these trends have basically ended the possibility of universal health care in the United States and elsewhere around the world. He concludes with suggestions for reform of our currently corrupted evidence-based medical system.

The Rise and Fall of Modern Medicine

Revised Edition

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Author: James Le Fanu M.D.,James Fanu

Publisher: Basic Books

ISBN: 0465058892

Category: Medical

Page: 608

View: 7121

The medical achievements of the post-war years rank as one of the supreme epochs of human endeavour. Advances in surgical technique, new ideas about the nature of disease and huge innovations in drug manufacture vanquished most common causes of early death, But, since the mid-1970s the rate of development has slowed, and the future of medicine is uncertain. How has this happened? James Le Fanu's hugely acclaimed survey of the 'twelve definitive moments' of modern medicine and the intellectual vacuum which followed them has been fully revised and updated for this edition. "The rise and fall of modern medicine" is both riveting drama and a clarion call for change.

Overdiagnosed

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Author: H. Gilbert Welch

Publisher: Beacon Press

ISBN: 0807022012

Category: Medical

Page: 248

View: 3693

From a nationally recognized expert, an exposé of the worst excesses of our zeal for medical testing Going against the conventional wisdom reinforced by the medical establishment and Big Pharma that more screening is the best preventative medicine, Dr. Gilbert Welch builds a compelling counterargument that what we need are fewer, not more, diagnoses. Documenting the excesses of American medical practice that labels far too many of us as sick, Welch examines the social, ethical, and economic ramifications of a health-care system that unnecessarily diagnoses and treats patients, most of whom will not benefit from treatment, might be harmed by it, and would arguably be better off without screening. Drawing on twenty-five years of medical practice and research on the effects of medical testing, Welch explains in a straightforward, jargon-free style how the cutoffs for treating a person with "abnormal" test results have been drastically lowered just when technological advances have allowed us to see more and more "abnormalities," many of which will pose fewer health complications than the procedures that ostensibly cure them. Citing studies that show that 10 percent of two thousand healthy people were found to have had silent strokes, and that well over half of men over age sixty have traces of prostate cancer but no impairment, Welch reveals overdiagnosis to be rampant for numerous conditions and diseases, including diabetes, high cholesterol, osteoporosis, gallstones, abdominal aortic aneuryisms, blood clots, as well as skin, prostate, breast, and lung cancers. With genetic and prenatal screening now common, patients are being diagnosed not with disease but with "pre-disease" or for being at "high risk" of developing disease. Revealing the economic and medical forces that contribute to overdiagnosis, Welch makes a reasoned call for change that would save us from countless unneeded surgeries, excessive worry, and exorbitant costs, all while maintaining a balanced view of both the potential benefits and harms of diagnosis. Drawing on data, clinical studies, and anecdotes from his own practice, Welch builds a solid, accessible case against the belief that more screening always improves health care.

I Think You'll Find It's a Bit More Complicated Than That

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Author: Ben Goldacre

Publisher: Fourth Estate

ISBN: 9780007505142

Category: Medicine, Popular

Page: 496

View: 7339

The very best journalism from one of Britain's most admired and outspoken science writers, author of the bestselling Bad Science and Bad Pharma. In Bad Science, Ben Goldacre hilariously exposed the tricks that quacks and journalists use to distort science. In Bad Pharma, he put the $600 billion global pharmaceutical industry under the microscope. Now the pick of the journalism by one of our wittiiest, most indignant and most fearless commentators on the worlds of medicine and science is collected in one volume.

Overdosed America

The Broken Promise of American Medicine

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Author: Dr. John Abramson

Publisher: Harper Collins

ISBN: 0062281437

Category: Medical

Page: 384

View: 7632

Using the examples of Vioxx, Celebrex, cholesterol-lowering statin drugs, and anti-depressants, Overdosed America shows that at the heart of the current crisis in American medicine lies the commercialization of medical knowledge itself. Drawing on his background in statistics, epidemiology, and health policy, John Abramson, M.D., reveals the ways in which the drug companies have misrepresented statistical evidence, misled doctors, and compromised our health. The good news is that the best scientific evidence shows that reclaiming responsibility for your own health is often far more effective than taking the latest blockbuster drug. You—and your doctor—will be stunned by this unflinching exposé of American medicine.

Testing Treatments

Better Research for Better Healthcare

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Author: Imogen Evans,Hazel Thornton,Iain Chalmers,Paul Glasziou

Publisher: Pinter & Martin Publishers

ISBN: 1905177488

Category: Health & Fitness

Page: 199

View: 9319

This work provides a thought-provoking account of how medical treatments can be tested with unbiased or 'fair' trials and explains how patients can work with doctors to achieve this vital goal. It spans the gamut of therapy from mastectomy to thalidomide and explores a vast range of case studies.

The Patient Paradox

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Author: Margaret McCartney

Publisher: Pinter & Martin Publishers

ISBN: 1780660006

Category: Medical

Page: 335

View: 2472

Welcome to the world of sexed-up medicine, where patients have been turned into customers, and clinics and waiting rooms are jammed with healthy people, lured in to have their blood pressure taken and cholesterol, smear test, bowel or breast screening done. In the world of sexed-up medicine pharmaceutical companies gloss over research they don’t like and charities often use dubious science and dodgy PR to 'raise awareness' of their disease, leaving a legacy of misinformation in their wake. Our obsession with screening swallows up the time of NHS staff and the money of healthy people who pay thousands to private companies for tests they don’t need. Meanwhile, the truly sick are left to wrestle with disjointed services and confusing options. Explaining the truth behind the screening statistics and investigating the evidence behind the hype, Margaret McCartney, an award-winning writer and doctor, argues that this patient paradox – too much testing of well people and not enough care for the sick – worsens health inequalities and drains professionalism, harming both those who need treatment and those who don't.

Trick Or Treatment?

Alternative Medicine on Trial

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Author: Simon Singh,Edzard Ernst

Publisher: Corgi Books

ISBN: 9780552157629

Category: Alternative medicine

Page: 416

View: 8708

In this groundbreaking analysis, more than 30 of the most popular alternative healing treatments--acupuncture, homeopathy, aromatherapy, reflexology, chiropractic, and herbal medicines--are examined for their benefits and potential dangers. 16 illustrations.

An American Sickness

How Healthcare Became Big Business and How You Can Take It Back

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Author: Elisabeth Rosenthal

Publisher: Penguin

ISBN: 0143110853

Category: Business & Economics

Page: 432

View: 6422

"An award-winning New York Times reporter Dr. Elisabeth Rosenthal reveals the dangerous, expensive, and dysfunctional American healthcare system, and tells us exactly what we can do to solve its myriad of problems. It is well documented that our healthcare system has grave problems, but how, in only a matter of decades, did things get this bad? Dr. Elisabeth Rosenthal doesn't just explain the symptoms; she diagnoses and treats the disease itself. Rosenthal spells out in clear and practical terms exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship, explaining step by step the workings of a profession sorely lacking transparency. This is about what we can do, as individual patients, both to navigate a byzantine system and also to demand far-reaching reform. Breaking down the monolithic business into its individual industries--the hospitals, doctors, insurance companies, drug manufacturers--that together constitute our healthcare system, Rosenthal tells the story of the history of American medicine as never before. The situation is far worse than we think, and it has become like that much more recently than we realize. Hospitals, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Americans are dying from routine medical conditions when affordable and straightforward solutions exist. Dr. Rosenthal explains for the first time how various social and financial incentives have encouraged a disastrous and immoral system to spring uporganicallyin a shockingly short span of time. The system is in tatters, but we can fight back. An American Sicknessis the frontline defense against a healthcare system that no longer has our well-being at heart"--

The Art of Data Analysis

How to Answer Almost Any Question Using Basic Statistics

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Author: Kristin H. Jarman

Publisher: John Wiley & Sons

ISBN: 1118413342

Category: Mathematics

Page: 190

View: 8556

A friendly and accessible approach to applying statistics in the real world With an emphasis on critical thinking, The Art of Data Analysis: How to Answer Almost Any Question Using Basic Statistics presents fun and unique examples, guides readers through the entire data collection and analysis process, and introduces basic statistical concepts along the way. Leaving proofs and complicated mathematics behind, the author portrays the more engaging side of statistics and emphasizes its role as a problem-solving tool. In addition, light-hearted case studies illustrate the application of statistics to real data analyses, highlighting the strengths and weaknesses of commonly used techniques. Written for the growing academic and industrial population that uses statistics in everyday life, The Art of Data Analysis: How to Answer Almost Any Question Using Basic Statistics highlights important issues that often arise when collecting and sifting through data. Featured concepts include: • Descriptive statistics • Analysis of variance • Probability and sample distributions • Confidence intervals • Hypothesis tests • Regression • Statistical correlation • Data collection • Statistical analysis with graphs Fun and inviting from beginning to end, The Art of Data Analysis is an ideal book for students as well as managers and researchers in industry, medicine, or government who face statistical questions and are in need of an intuitive understanding of basic statistical reasoning.

The Drugs Don't Work

A Global Threat

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Author: Professor Dame Sally Davies,Jonathan Grant,Mike Catchpole

Publisher: Penguin UK

ISBN: 0241968887

Category: Social Science

Page: 50

View: 1301

The Drugs Don't Work - A Penguin Special by Professor Dame Sally Davies, the Chief Medical Officer for England 'If we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again' David Cameron, Prime Minister Resistance to our current range of antibiotics is the new inconvenient truth. If we don't act now, we risk the health of our parents, our children and our grandchildren. Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food. No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily. This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall. Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College. Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics. Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.

The Antidote

Inside the World of New Pharma

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Author: Barry Werth

Publisher: Simon and Schuster

ISBN: 1451655665

Category: Business & Economics

Page: 448

View: 2345

Documents the story of maverick pharmaceutical company Vertex and a small team of entrepreneurial scientists who after dissociating themselves from Merck endeavored to create breakthrough medicines and transform the pharmaceutical industry. By the award-winning author of The Billion-Dollar Molecule.

The UltraMind Solution

Fix Your Broken Brain by Healing Your Body First

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Author: Mark Hyman

Publisher: Simon and Schuster

ISBN: 1416566058

Category: Self-Help

Page: 464

View: 7501

A hidden epidemic races around the globe -- we can't see it or touch it, which makes it so dangerous. The invisible epidemic has led to the suffering of millions who spend billions on drugs, only to find they don't work. This is an epidemic of broken brains. "Broken brains" go by many names -- depression, anxiety, memory loss, brain fog, attention deficit disorder, autism, and dementia, to name a few -- and show up in radically different ways from person to person, making each seem like a separate problem. But the truth is that these "diagnoses" are all the result of a few basic problems with our biology. Pinpoint these biological problems, fix them, and let your body's natural healing intelligence take over to repair your brain. Now you can experience an UltraMind -- one that is highly focused and able to pay attention at will, with a strong, reliable memory and a mood that is calm, confident, in control, and in good spirits. We have all heard of the mind-body connection or how our thoughts affect the health of our body. But the reverse is far more powerful: what you do to your body, your basic biology, has a profound effect on your brain. Have you ever experienced instant clarity after exercise? Alertness after drinking coffee? A mental crash after popping candy? Does your brain inexplicably slow down during stress, while multitasking, or when meeting a deadline? Each is an example of how what we do to our bodies -- whether through nutrition, sleep, exercise, or stress -- has a dramatic effect on our brains. Conventional treatments don't help, or provide only slight benefit, because they just manage symptoms rather than deal with -- and heal -- the underlying problem. And just as brain problems all stem from the same root causes, they all have the same solution -- The UltraMind Solution. Our ancient genes interact with our environment to create systemic imbalances that affect our brains. Correct those imbalances -- most caused by nutritional deficiencies, allergens, infections, toxins, and stress -- and you can achieve optimum mental health without drugs or psychotherapy. The UltraMind Solution is the future of medicine, the culmination of the last twenty years of research on what makes the brain happy, focused, and calm; research that has uncovered a few simple factors that explain why things go wrong and how to fix them. Don't wait for this revolution in medicine to trickle into your doctor's office: it usually takes research twenty years to move from the lab to the patient. The answers are here, right now, in The UltraMind Solution.

Overtreated

Why Too Much Medicine Is Making Us Sicker and Poorer

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Author: Shannon Brownlee

Publisher: Bloomsbury Publishing USA

ISBN: 9781596917293

Category: Medical

Page: 368

View: 6214

Our health care is staggeringly expensive, yet one in six Americans has no health insurance. We have some of the most skilled physicians in the world, yet one hundred thousand patients die each year from medical errors. In this gripping, eye-opening book, award-winning journalist Shannon Brownlee takes readers inside the hospital to dismantle some of our most venerated myths about American medicine. Brownlee dissects what she calls "the medical-industrial complex" and lays bare the backward economic incentives embedded in our system, revealing a stunning portrait of the care we now receive. Nevertheless, Overtreated ultimately conveys a message of hope by reframing the debate over health care reform. It offers a way to control costs and cover the uninsured, while simultaneously improving the quality of American medicine. Shannon Brownlee's humane, intelligent, and penetrating analysis empowers readers to avoid the perils of overtreatment, as well as pointing the way to better health care for everyone.

The Truth About The Drug Companies

How They Deceive Us And What To Do About It

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Author: Marcia Angell

Publisher: Random House Incorporated

ISBN: 0375760946

Category: Medical

Page: 319

View: 2514

A physician and former editor-in-chief of The New England Journal of Medicine provides an explosive critique of the pharmaceutical industry, detailing its dangerous influence on medical research, education, and physicians; exposing the reasons behind the spiraling prescription drug prices; and proposing a program of vital reforms. Reprint.